PubMed Health⌕ Search

Biomedical subjects

M Haller

Publications and source records attributed to M Haller.

115 records · Page 7Linked to original sources

Single-injection inulin clearance--a simple method for measuring glomerular filtration rate in dogs.

The glomerular filtration rates (GFR) of 93 dogs of different breeds with a broad range of bodyweight were determined using an inulin single-injection method. Fifty-two dogs were used as controls, 21 dogs had suspected renal disease but serum creatinine in the normal range, and 20 dogs had elevated serum creatinine levels and a low urine specific gravity due to renal disease. Inulin was injected intravenously at a dosage of 100 mg kg(-1) bodyweight or 3000 mg m(-2) body surface. Blood samples were taken before and three, 20, 40, 80 and 120 minutes after injection. The total clearance was calculated from the decrease in the serum concentration of inulin using a two-compartment model. The range of GFR values was 83.5-144.3 ml min(-1) m(-2) in control dogs, 60.2-96.7 ml min(-1) m(-2) in dogs with suspected renal disease, 50.0-76.2 ml min(-1) m(-2) in dogs with suspected renal disease and polyuria/polydipsia, and 16.3-63.0 ml min(-1) m(-2) in dogs with azotaemic renal disease. The study indicates that single-injection inulin clearance is a cheap and simple tool for GFR measurements in small animal practice.

Animals↗

[Quantification of position-related errors in measurement of antetorsion of the femur with computerized tomography--introduction of a method for positional correction].

OBJECTIVE: To quantify the influence of patient positioning on the determination of collodiaphyseal (CCD) angle and femoral neck anteversion based on computed tomography. Description of a method for positional correction. METHODS: We evaluated the CT scans of 84 femora from 77 patients, who received individually adapted prostheses. Projected as well as real anteversion and CCD angles were determined and corrected for positioning errors using a newly proposed mathematical method, and compared to other evaluation methods. RESULTS AND CONCLUSIONS: We determined an average tilt of 4.2 degrees in the sagittal and of 9 degrees in the coronary plane, which correlated definitely with the deviations found in the graphical determination of the projected anteversion angle. This produced measurement errors of the projected anteversion angle of up to 10 degrees. Mathematically independent angles, such as projected anteversion and real CCD angle, showed only a weak correlation. This indicates also an anatomical independence of these angles.

Adult↗

Surgical and chemotherapeutic treatment of alveolar echinococcosis in a dog.

Surgical removal of macroscopically detectable metacestode tissue followed by postoperative chemotherapy according to established human protocols resulted in complete clinical remission and immediate normalization of hyperglobulinemia in a dog with alveolar echinococcosis (AE). The disease is caused by the metacestode stage of the cestode, Echinococcus multilocularis. In endemic areas, AE should be included in the differential diagnosis of polycystic liver masses, especially if concomitant hyperglobulinemia is present. However, the importance of AE is not only the disease of the single dog itself but also the potential risk of infection for humans in an endemic area.

Albendazole↗