A route dependent bioavailability in active metabolite suggested in riboflavin-5'-phosphate pharmacokinetics.
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Animals↗
Biomedical subjects
M Hanano
Publications and source records attributed to M Hanano.
Beneficial effect of minidose heparin in experimental peritonitis.
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Animals↗
Simple method of hepatic venous blood sampling in the rat.
An improved method of hepatic venous blood sampling by catheterization in rats is proposed and applied to the measurement of hepatic blood flow (HBF) by the continuous ICG infusion method in normal rats and in rats treated chronically with CC1(4). The value of HBF determined by the present method was 0.90 +/- 0.17 (SD) ml/min per g liver under ether anesthesia, which was consistent with the reported values determined by other more complicated methods. The applicability of the present method was also shown in CC1(4) chronic intoxicated rats, to give 0.64 +/- 0.11 ml/min per g liver of HBF.
Animals↗
Differences in species of iodochlorhydroxyquin absorption, metabolism, and excretion.
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Adult↗
Various factors affecting intestinal absorption of iodochlorhydroxyquin in rat and man.
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Adult↗
The effect of dosage form on absorption of vitamin A into lymph.
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Absorption↗
[Kinetics on uptake of drugs in goldfish III Excretion of salicylic acid,benzoic acid, phenol and phenobarbital from goldfish (author's transl)].
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Animals↗
[Kinetics on uptake of drugs in goldfish. II. Uptake of benzoic acid, phenol, phenobarbital and pentobarbital (author's transl)].
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Absorption↗
Conformational changes of human serum albumin by binding of small molecules.
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Humans↗
[Pharmacokinetics on drug interaction: effect of zoxazolamine on the plasma concentration time course of chlorzoxazone].
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Animals↗
[Kinetics on uptake of drugs in goldfish. I. Effect of pH change in water phase and addition of polyethylene glycol 6000 and urea on uptake of salicylic acid (author's transl)].
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Animals↗
Pharmacokinetic aspects of elimination from plasma and distribution to brain and liver of barbiturates in rat.
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Animals↗
[A pharmacokinetic study on the metabolism and excretion of sulpyrin in the rats (author's transl)].
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Animals↗
[The dose effect of sulpyrin on the metabolism and excretion rates in rats (author's transl)].
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Animals↗
[The effect of administration routes on the absorption, metabolism and excretion of sulpyrin in rats (author's transl)].
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Administration, Oral↗
Pharmacokinetic studies of biliary excretion. IV. The relationship between the biliary excretion behavior and the elimination from plasma of azo dyes and triphenylmethane dyes in rat.
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Animals↗
[Biopharmaceutical studies on indomethacin. I. Analysis of concentration time course in rabbit plasma after intravenous administration and relationship between dosage form and absorption after intraduodenal administration].
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Animals↗
[Biopharmaceutical studies on indomethacin. II. Mechanism of intestinal absorption of indomethacin in rat in vitro and availability of micronized powder after oral administration to man].
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Administration, Oral↗