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Biomedical subjects

M Hardjasudarma

Publications and source records attributed to M Hardjasudarma.

25 records · Page 2Linked to original sources

Central pontine myelinolysis as a manifestation of the paraneoplastic syndrome.

We have described a patient who had lung carcinoma, syndrome of inappropriate antidiuretic hormone, and central pontine myelinolysis (CPM). Although this association is well-known, it appears to be the first report having radiographic documentation of both the intracranial and intrathoracic abnormalities. When searching for the cause of CPM, the possibility of an underlying malignancy should also be considered. This may be more common than the radiology literature would suggest.

Adult↗

Gadopentetate dimeglumine in craniospinal magnetic resonance imaging: common uses and some potential pitfalls.

In the first few years since its release for clinical use gadopentetate dimeglumine has become an integral part of craniospinal magnetic resonance imaging (MRI). Its efficacy and high degree of safety, as well as patient tolerance of the contrast medium, have made it indispensable for imaging small acoustic neuromas, metastases, meningeal disease, intramedullary tumours and recurrent disk disease. In addition, its utility for imaging other abnormalities is being increasingly recognized. Because the mechanism of this compound differs from those of other contrast agents, the pitfalls it can create are also different. Better and more affordable contrast media are expected to further increase the practice of gadolinium-enhanced MRI.

Adult↗

Craniospinal magnetic resonance imaging enhanced with Gd-DTPA in von Hippel-Lindau disease.

The case presented illustrates the utility of enhancement with gadolinium diethylenetriaminepenta-acetic acid in magnetic resonance imaging (MRI) of the brain and the spinal cord in a patient with von Hippel-Lindau disease. The patient had numerous lesions in the brain stem and the cervical and the thoracic spinal cord, most of which were not demonstrated or were only poorly demonstrated with noncontrast MRI. Contrast-enhanced MRI should be performed in two sessions with a separate dose of contrast agent for each. Regular follow-up examinations should be conducted in the same manner.

Adult↗

Hypersexuality in stroke.

Hyposexuality is a common problem in stroke patients. Some stroke patients, however, may present with hypersexuality. We report three stroke patients who demonstrated hypersexuality and deviant sexual behavior after stroke. Abnormal sexual behavior was noted by members of the stroke rehabilitation team while the patients were in hospital. Details of pre- and poststroke sexual activity were obtained from patients and their spouses. All three patients had temporal lobe lesions on computerized tomography, and all had a history of poststroke seizure activity. The 53-year-old man reported poststroke increase in libido and coital frequency with a tendency towards priapism. The two women (47 and 55 years old) exhibited deviant sexual behavior, mood changes, and hyperphagia. The exact cause of these behavior changes is unknown but they may be related to temporal lobe involvement. Hypersexuality has previously been reported in animals and in patients with temporal lobe seizures.

Cerebrovascular Disorders↗

Adult diastematomyelia: a complex dysraphic state.

It is rare for patients with diastematomyelia to manifest initial symptoms in adult life. Clinical, radiological, and surgical features of a patient with symptomatic adult diastematomyelia are presented. Pathogenetic mechanisms are considered to include a variety of congenital spinal anomalies, distinct from the spur, as well as mechanical factors.

Adult↗