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Biomedical subjects

M Harms

Publications and source records attributed to M Harms.

15 recordsLinked to original sources
PubMed1992

[Bacillary angiomatosis: apropos of a case].

We report a case of bacillary angiomatosis (BA), a recently described opportunistic infection, in a 30-year-old patient with Aids who was referred for a purplish vascular nodule on the forehead, of one-month duration, surrounded by similar smaller papules. For the previous 4 months he had suffered from progressive cachexia with fever, chills, night sweats, arthralgias and bone pain for which no infectious or malignant cause had been discovered after an extensive medical work-up. Histological examination of the skin lesions using Warthin-Starry staining revealed lobular vascular proliferation and protuberant endothelial cells with clumps of small bacilli. These findings were confirmed by electron microscopy. We believe that this is the first case of BA diagnosed in Switzerland and discuss the skin lesions, systemic symptoms and evolution under antibiotic treatment.

Acquired Immunodeficiency Syndrome↗
PubMed1992

Orbital and palpebral paraffinoma.

Paraffinoma is a well-recognized complication of paraffin injection. We describe a 44-year-old man who had an ethmoidectomy for chronic sinusitis. A communicating fracture of the ethmoid bone into the orbit occurred intraoperatively. The nasal cavity was subsequently packed with gauze containing a petrolatum-based antibiotic ointment. Bilateral, periocular swelling developed 1 week later. Optical and electron microscopic studies revealed a paraffinoma.

Administration, Intranasal↗
PubMed1992

Systemic corticosteroids do not prevent postherpetic neuralgia.

We review the use of corticosteroids in preventing postherpetic neuralgia (PHN) in a retrospective study over 5 years and 10 months. Out of 113 patients evaluable, 46 (40%) had PHN. 21 of these 46 patients (38%) had received prednisone (p = 0.49; n.s.). Duration and intensity of PHN were not different in the prednisone-treated group. This long-term study does not support the use of prednisone for preventing PHN.

Female↗
PubMed1992

Histiocytic lymphophagocytic panniculitis (Rosai-Dorfman disease): a case report.

A 68-year-old woman presented with a symmetrical enlargement of the face and submandibular area associated with essential thrombocytosis. Biopsy of the lesions revealed a septal and lobular panniculitis disclosing a lymphohistiocytic and plasma cell proliferation with lymphophagocytosis by histiocytes, compatible with Rosai-Dorfman disease. The lesions regressed spontaneously without therapy over a period of 4 months. Diagnosis was confirmed by electron-microscopic examination and immunocytochemical presence of S-100 antigen within the histiocytic cells. A 2-year follow-up did not demonstrate any evidence of recurrence.

Aged↗
PubMed1991

[The significance of protein C deficiency in dermatology].

The protein C system is a physiological inhibitor of coagulation and is important for the regulation of hemostasis. Protein C deficiencies can be inherited or acquired, and they lead to enhanced thrombophilia. A number of clinical entities that are also of interest to dermatologists have been related to protein C deficiency. Inherited protein C deficiency can become manifest in various ways, e.g. as purpura fulminans neonatalis, as recurrent episodes of thrombosis and as coumarin necrosis. Acquired protein C deficiency can be observed in the course of purpura fulminans, disseminated intravascular coagulation, hepatic failure or in the presence of antiphospholipid antibodies. The clinical features, the possible pathogenesis and the therapy of these manifestations are briefly discussed.

Humans↗
PubMed1978

[Cutaneous plasmacytosis and polyclonal cryo-immunoglobulinemia].

A 65-year-old male patient is described who presented with (1) large violet cutaneous plaques on the left side of the body, characterized by dense plasmocyte infiltration of the dermis which appeared benign and largely negative to immunofluorescence, (2) massive polyclonal cryoglobulinemia (type III) without paraproteins, and (3) intermittently marked peripheral monocytosis and thrombopenia without significant medullary changes. Compared with the cases reported in the literature, and after a thorough immunological investigation, this syndrome cannot be entirely assimilated to any entity described up to the present time. Hypothetically, a reactional disorder is the most likely.

Aged↗
PubMed1977

[Demonstrations].

Explore the source record for details and available documents.

Adolescent↗
PubMed1976

Experimental keratocanthoma [author's transl].

After topical application of the carcinogen DMBA on the rabbit's ear, tumors will always appear. These are clinically characterized by their important hyperkeratosis. Some of these tumors develop rapidly and disappear completely as do KA. Others do not reach such an important size but do not regress. None of these tumors looked like a malignant tumor and did not show signs of invasiveness nor metastasis. However the histological findings reveal in some cases precancerous and malignant aspects. The number of tumors can be increased by lengthening the application time of the carcinogen, by modifying the mode of application (repeated application and transport medium DMSO) and by irradiation.

9,10-Dimethyl-1,2-benzanthracene↗
PubMed1975

[Plasmacytic reticulosis].

The authors observed one case of plasmocytic reticulosis which was noticable by its strictly left unilateral localisation, involving the face, the underscapular region, the shoulder and the elbow, the leg with an important augmentation of the left foot. Histologically, dense plasmocytic infiltration can be observed without anomalies. Electron microscopy confirmes the presence of plasmocytes at any stage of activity without monstruosities. This observation can not be classified in the forms that are actually described: Klüken's and Simonis' plasmocytic reticulosis, plasmocytomas with osseous and medullar lesions, extramedullar plasmocytoma.

Aged↗