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Biomedical subjects

M Harri

Publications and source records attributed to M Harri.

At least 19 recordsLinked to original sources

Trade-off between floor level and floor material in farmed silver foxes.

Farmed silver foxes (Vulpes vulpes) were allowed to balance their known preference for an elevated floor against their presumed preference for a sand floor. In Experiment 1, foxes had to choose between two identical cages, connected with an opening. One cage had a wire floor and the other had a sand floor, but the cages either were on the same (low or elevated) or on different levels (one cage 40 cm higher than the other). In Experiment 2, the cage pairs were connected with a 1.2 m long wire-mesh tunnel, one cage was always on a higher level (50 cm) than the other. In Experiment 1, foxes always preferred the sand floor during their active time. They also preferred the sand floor for resting, if it was on the same level as wire floor, but did not show any genuine preference if the floors were on different levels. In Experiment 2, foxes never preferred the lower floor. They preferred the elevated sand floor for activity and the elevated wire floor for lying. When two floors were identical they preferred the elevated one. Their rest consisted of 11-22 bouts, a major part of these being spent in the preferred cage. They also preferred a previous lying site to a new one, often exclusively and independently of floor material. In Experiment 1 foxes preferred the sand floor whereas in Experiment 2 they preferred the elevated floor indicating that the ability of a trade-off situation to rank resources depends on the method it is inflicted.

Journal Article↗

Observations on thermoregulatory ontogeny of mink (Mustela vison).

(1) We measured cooling rate for neonatal mink during a 10min coldroom (3.9 degrees C) exposure and subsequent warming rate during a 20min incubator (37.2 degrees C) exposure, the behaviour of the kits and the changes in their pelage between 1 and 46d of age, in an attempt to monitor the ontogeny of their thermoregulatory capacity. (2) Body weight of the 1d old kits averaged only 12.8+/-2.3g (n=4), but they gained weight rapidly reaching 226.1+/-28.3g (males, n=4) and 207.6+/-16.1g (females, n=4) at 30-31d of age, and 562.3+/-43.2g (males, n=3) and 435.7+/-35.5g (females, n=4) at 45-46d of age. (3) Body cooling rate (C(rate) ( degrees C/min); n=80) was affected by the age (between 1 and 31d), BW, initial rectal temperature (T(r0)), and sex of the kits, in addition to their body posture (P(cold), 1=extended, 2=curled-up) during coldroom exposure. C(rate) ( degrees C/min)=-0.34-0.02age-0.002BW+0.05T(r0)-0.06sex-0.20P(cold) (R(2)=0.75). (4) Body warming rate (W(rate) ( degrees C/min); n=80) was influenced by the age(2) and rectal temperature of the kit after the coldroom exposure (T(r10)). W(rate)( degrees C/min)=1.24+0.0002age(2)-0.04T(r10) (R(2)=0.76). (5) Kit fur fibre length increased from 5.45+/-0.63mm (males, n=2) and 6.20+/-0.20mm (females, n=3) at 22-23d of age to 9.43+/-1.44mm (males, n=4) and 8.70+/-1.89mm (females, n=4) at 30-31d of age, and to 12.93+/-0.47mm (males, n=3) and 11.38+/-0.41mm (females, n=4) at 45-46d of age, the growth averaging about 0.26mm per day. (6) Under normal circumstances newborn mink kits are hypothermic.Their thermoregulation develops only gradually and is dependent on increase in body mass, insulation and behavioural thermoregulation. Their strategy of survival is based on the ability to withstand hypothermia and on the nutrition and warmth provided by the dam.

Journal Article↗

Preferences of farmed blue foxes for different floor types.

In the first experiment, farmed blue foxes were allowed to choose for 1 week between four standard farm cages equipped with different floor materials: plastic-coated wire mesh, dry wood, dry sand and wet (summer) or icy (winter) sand. Resting consisted of 10-15 separate bouts/day occupying 50-60% of the total 24-h. There were no other differences in the use of the cages except that the time spent on, and the duration and number of resting bouts were lower on wet or icy sand, resting periods being more affected than activity. In the second experiment, two cages were connected with a 1.2 m tunnel. One cage was always elevated (50 cm) compared to that one which was lower. One cage of each pair had a wire floor whereas the other cage either had sand or wire floor. Sand floor was preferred for active behaviours and wire floor for resting if these were on elevated level. Of two identical wire-floored cages, the elevated one had the priority. Foxes preferred to rest on the same floor where they had finished their previous resting bout, often exclusively and independently of floor material or floor level.

Journal Article↗

Effect of access to a running wheel on behavior of C57BL/6J mice.

BACKGROUND AND PURPOSE: To evaluate how and when mice run on a running wheel and how ad libitum access to the wheel affect behavior, feed intake, and weight gain. METHODS: Seventeen 2-month-old C57BL/6J mice had access to the wheel, whereas 19 control mice did not. After 3 to 6.5 weeks, behavior was video-recorded over 24 h for each mouse. RESULTS: Experimental mice ran an average 2 km/24 h in 114 min. Highest running activity took place at the onset of darkness. Experimental mice spent 22 min more feeding on the cage floor than did control mice. These times were deducted from those for all other behaviors: 74 min from resting time, 39 min from climbing and feeding on the cage lid, 14 min from locomotion on the cage floor, and 10 min from grooming. In relative figures, deduction from sleeping time was only 9%, whereas climbing time was halved. CONCLUSIONS: Climbing on the cage lid has a similar circadian rhythm as does wheel running and high-energy expenditure. Because experimental mice climbed less, their weight gain and feed intake were similar to those of control mice. Thus, wheel running can substitute for other forms of energy-consuming behaviors and vice versa.

Animals↗

Mercury-binding capacity of organic and inorganic selenium in rat blood and liver.

The mercury-binding capacity of seleno-DL-methionine and selenium dioxide was assessed in male Wistar rats. Mercury was supplied as fish loaves made of northern pike or rainbow trout. We used a selenium concentration of 3.4 mg/kg fish, about sixfold compared to the equivalent quantity of mercury. Seleno-DL-methionine had a tendency to increase both methyl mercury and total mercury in blood, although it also seemed to reduce the proportion of methyl mercury of total mercury. Selenium dioxide lowered mercury levels by 24-29% both in the blood and in the liver of rats that were fed with northern pike.

Animals↗

The sense of coherence among nurse educators in Finland.

In his salutogenic model, Antonovsky defines the sense of coherence (SOC) as a personality dimension which is hypothesized to facilitate stress management and to contribute to overall well-being. The SOC scores of Finnish nurse educators were determined using the 13-item version of the SOC questionnaire. Questionnaires were sent to 706 Finnish nurse educators, and data from 477 (68%) educators were analysed. The mean score of respondents' SOC was 66.9 (SD 0.47, range 34-88). Cronbach's alpha was 0.81. The SOC was lower among older respondents. The more freedom individuals had to choose their teaching field, the higher the SOC. Thus, although age explained a significant proportion of variance, its contribution to the total proportion of variance explained was quantitatively less important than that of freedom to choose duties. Other background data were not related to SOC. There was a significant positive relationship between the SOC score and the opinions of nurse educators about interaction in the working community, joy of work, workload, negative stress, symptoms of diseases, atmosphere in the college, evaluation of own competence, balance between work and leisure time, own health, and use of drugs.

Adaptation, Psychological↗

Validation of the feeding test as an index of fear in farmed blue (Alopex lagopus) and silver foxes (Vulpes vulpes).

The reliability and validity of the eating behaviour in the presence of man (Feeding test) as an index of fear were assessed in farmed blue (Alopex lagopus) and silver foxes (Vulpes vulpes). Repeatability of the Feeding test was good in both species. No further habituation occurred after the fourth successive test in either species. In addition, the behaviour of both species was independent of the person who performed the test. The normal feeding interval, i.e., 24 h, between feed deliveries, was long enough to provide reliable results. The presence of a cage mate did not influence the blue foxes' response in the Feeding test. A significant relationship between the results of the Feeding test and the Tit-bit test in both species and between the Feeding test and fearfulness score in silver foxes indicate that all these tests measure similar features, most probably foxes' fear of humans. Those silver foxes that did not eat in the Feeding test had higher base levels of cortisol than the animals that did eat, providing further support for the above conclusion. The present study demonstrates that the Feeding test is a reliable, i.e., repeatable and free of random errors, and fairly valid fear test for blue and silver foxes. The Feeding test seems likely to give good results in measuring fear in farmed blue and silver foxes, but further investigations will be needed to fully validate it, especially for blue foxes.

Animals↗

How do nurse educators respond to the challenges and changes in their working life in Finland?

In the present study nurse educators were asked to comment via a questionnaire on the characteristics deriving from earlier results and how they experience the present situation in their working life, and how they see the future. Data from 65 (63% of 104) educators were analysed. The earlier results, in the form of statements describing the best and the worst things in nurse educators' working life, were generally corroborated by respondents. The best things were students, freedom and challenges, and the worst things were workload, inadequacy of personal resources and administrative issues at work. Agreement was most clear on the workload being the worst thing in nurse educators' working life (52 out of 65). The explanations for agreement and disagreement were much the same as those given in previous studies. Regarding the present situation and the most important thing that needs attention in nurse educators' working life in Finland, nurse educators named continuous and too rapid changes. These results are related to workload, excessive demands and stress, competition, feelings of insecurity, and everlasting pressure to educate oneself. On the other hand, one's perception of working life is a very personal issue, and some educators who cope with it keep challenges as possibilities and enjoy them.

Adaptation, Psychological↗

'I love my work, but ... ': the 'best' and the 'worst' in nurse educators' working life in Finland.

The aim of this study was to investigate nurse educators' perceptions of the quality of their working life. Questionnaires were sent to 706 Finnish nurse educators and their spouses or other adult living with them. The results concerning the structured part of the questionnaire have been described in detail in an earlier paper (Harri 1995). This paper describes the data collected by means of semi-structured questions from 477 (68%) educators and 409 (58%) spouses) and open-ended questions (309 nurse educators and 167 spouses), analysed using content analysis. The seven categories that were identified as the best features of work were, in descending order of prevalence: students, freedom, challenges, teaching, miscellaneous, colleagues, and physical environment. Among the worst features of work, workload ranked first, followed by inadequacy of personal resources, administrative issues, changes, interpersonal relationships, miscellaneous, and physical environment. In the open-ended comments the nurse educators used 400 expressions to describe positive features of their working life, while they used 597 expressions to describe negative features. The spouses made 90 positive comments about the working life of their teacher spouse, and 425 negative comments. The importance of this kind of study was remarked on quite frequently both by nurse educators (22%) and their spouses (12%). The study provides important clues to understanding the present reality of nurse educators' working life. It is hoped that the findings of the study will help focus attention on ways of developing the quality of nurse educators' working life.

Faculty, Nursing↗

Assessing the quality of the working life of nurse educators in Finland: perceptions of nurse educators and their spouses.

As part of a broader descriptive study of nurse educators' well-being at work in Finland, the quality of working life was assessed by the nurse educators themselves and by their spouses (or another adult living with them). Data were analysed from 477 (68% of 706) educators from 25 institutes throughout Finland and from 409 (58% of 706) spouses. Nurse educators evaluated their working life as being good. Background factors that improved one or several features of working life were: young age, being married, permanent employment in a small institute in the countryside, and highschool education. Lack of freedom to choose the teaching field and tasks at work reduced the quality of working life. Nurse educators estimated that they did an average of 9.6 hours overtime a week; according to their spouses the figure was 12.7 hours. More than moderate amounts of negative stress, derived mainly from work, were reported. Interactions with people at work and the support obtained for their work were generally judged to be good. Participants reported that they were not very satisfied with relationships with college directors, while they were, generally, satisfied with relationships with students. The spouses estimated nurse educators' working life more negatively than did the educators themselves, with the exception of the balance between work and leisure time, which both groups estimated similarly.

Adult↗

Mental wellbeing of nurse educators at work.

The aim of the study was to assess the mental wellbeing of nurse educators at their work by means of self-assessment. Questionnaires were sent to 100 randomly selected trained nurse educators. Data were collected from 83 respondents. The nurse educators evaluated their mental wellbeing as being rather good. There were, however, some contradictions in the answers to questions covering identical work areas but having somewhat different formulation. The disadvantages of being a nurse educator, as listed by the respondents, included: too much work, and especially too many administrative duties, communication breakdowns with the directors of the nursing college, and underestimation by others of the value of teaching as such. As characteristics of the job promoting a sense of wellbeing, the nurse educators mentioned their interaction and relationships with the students. In addition, the demands and challenges of the work were found very interesting and rewarding.

Adult↗

Induction of follicular development in silver foxes (Vulpes vulpes) with equine chorionic gonadotrophin (eCG) and antibodies against eCG.

Experiments were conducted that demonstrated that 1000 iu equine chorionic gonadotrophin (eCG) was effective in induction of follicular development and ovulation in silver foxes during anoestrus. This treatment resulted in large, unovulated follicles; thus, trials in which the effects of eCG were reduced or abrogated by antibodies against eCG were carried out. Passive immunization against eCG on days 3 and 4 after eCG treatment interfered with subsequent follicular development and prevented ovulation. Treatment with eCG antibodies on days 5 or 7 after eCG treatment did not prevent ovulation and neutralization beginning on day 5 appeared to provide for the best ovulatory yield. The results suggest that combinations of eCG and anti-eCG antibody may provide a useful means of inducing ovarian activity in anoestrous foxes.

Anestrus↗

Thermoregulatory responses to exercise at low ambient temperature performed after precooling or preheating procedures.

Seven male skiers exercised for 30 min on a cycle ergometer at 50% of maximal oxygen uptake and an ambient temperature of 5 degrees C. The exercise was preceded either by cold exposure (PREC) or active warming-up (PREH). The data were compared with control exercise (CONT) performed immediately after entering the thermal chamber from a thermoneutral environment. Cold exposure resulted in negative heat storage (96.1 kJ.m-2, SE 5.9) leading to significantly lower rectal, mean body and mean skin temperatures at the onset of exercise in PREC, as compared to PREH and CONT. The PREC-PREH temperature differences were still significant at the end of the exercise period. During exercise in the PREC test, oxygen uptake was higher than in PREH test (32.8 ml.kg-1.min-1, SE 1.5 vs 30.5 ml.kg-1.min-1, SE 1.3, respectively). Heart rate showed only a tendency to be higher in PREC than in PREH and CONT tests. In the PREH test skin and body temperatures as well as sweat rate were already elevated at the beginning of exercise. Exercise-induced changes in these variables were minimal. Heat storage decreased with the duration of the exercise. Exercise at low ambient temperature preceded by a 30-min rest in a cold environment requires more energy than the same exercise performed after PREH.

Adolescent↗

Effects of group and sex combination on productive performance of farmed polecats (Mustela putorius).

Effects of cage size, sex and social status on body growth and fur quality of juvenile, growing polecats (Mustela putorius) were studied under farm conditions. No significant differences in growth rate or fur quality parameters between various female groups were found. In males, animals housed by threes within a cage produced lowest final body mass and shortest pelt lengths. The best productive result was found in group where 2 males and 2 females were kept together in large-sized cages. In both sexes, social status did not produce any significant differences in body growth or fur quality parameters. The results support the conclusion that also other than the conventional one-male and one-female combination can be used to produce animals of big body size and long pelts.

Analysis of Variance↗

Effect of sport-drink with and without fluoride and magnesium supplements on rat performance.

Young Osborne-Mendel rats were given different diets ad libitum for 6 weeks. Food was either a purified powder with sucrose (15%) or commercial pellets, and drink was either distilled water or a sugar-containing (6%) sport-drink with or without added fluoride (F), magnesium (Mg) or both. Despite differences in the energy density of the diets, daily intakes were the same in terms of metabolisable energy and resulted in equal weight gains for all groups. Interscapular brown fat hypertrophied in response to powdered food, while both sugar-containing food and sport-drink were effective in accumulating white fat. When exposed to cold air at -20 degrees C for 2-4 h, most of the rats were able to maintain normothermia. Only the rats fed pelleted food and given distilled water were less resistant to cold than the others. After exposure to cold, the reserves of muscle glycogen were least in those rats having the poorest performance in the cold. In contrast, the stores of liver glycogen, plasma glucose and adrenal ascorbic acid were associated with pelleted food, rather than with the exposure to cold or type of drink. It is concluded that the presence of purified, simple sugars, either in food or drink, is the most likely explanation of the results obtained. The F and Mg supplements to the sport-drink did not modify the parameters measured.

Adipose Tissue↗

Regulation of weight loss in male farm mink.

1. Regulation of weight loss was studied in wild mink (Mustela vision) under farm conditions. 2. Body weight of male minks was already adjusted to a low level before the mating season. 3. Weight loss was a result of changes in energy expenditure and energy intake. 4. This study emphasizes the dynamic nature of seasonal energy regulation.

Animals↗