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Biomedical subjects

M Hasuo

Publications and source records attributed to M Hasuo.

At least 19 recordsLinked to original sources
PubMed2003

Two-photon excitation of excitons in CuCl in total reflection geometry.

We have observed emission spectra of a CuCl film on a TiO2 prism surface(110) associated with the two-photon excitation of the exciton system in total reflection geometry. The I1 bound exciton emission, which resonantly appeared at the two-photon excitation of the Z3-longitudinal excitons and Z1,2-exciton band, was observed. The dependence of the emission intensities on the polarization of the excitation light was explained from the field intensity and the penetration depth of the evanescent light in CuCl accompanying the totally reflected light at the TiO2/CuCl interface.

Copper↗
PubMed2000

Tributyrin specifically induces a lipase with a preference for the sn-2 position of triglyceride in Geotrichum sp. FO401B.

The extracellular Lipases A and C produced by Geotrichum sp. FO401B have a preference for the sn-1,3 and sn-2 positions of triglyceride, respectively. Total production of these lipases was increased by plant oils and tributyrin. Butyl Toyopearl column chromatography demonstrated that only Lipase C was produced in the presence of tributyrin. Lipase C hydrolysed natural fats except sardine oil preferentially at the sn-2 position, but it showed little stereoselectivity for triolein.

Enzyme Induction↗
PubMed1993

[Cranioplasty using cryopreserved autogenous bone].

Various materials and methods can be used for cranioplasty following external decompression craniotomy. We generally use cryopreserved autogenous bone for cranioplasty following external decompression. We assessed several factors, including histological changes in the stored bone, postoperative skull X-ray changes, postoperative changes in skull morphology, and the incidence of postoperative infections. The purpose of this study was determined if our materials and preservation methods were appropriate. The subjects were 110 patients who underwent cranioplasty using cryopreserved autogenous bone following external decompression at our hospital. They were followed up for at least one year. Bone fragments removed at the time of external decompression were stored at -40 degrees C an ultra-low temperature freezer and returned to room temperature before using them for cranioplasty. Follow-up skull x-ray films were obtained for 1-10 years postoperatively. Almost all of the 46 patients showed bone union at least one year after cranioplasty, but seven patients (15%) had marked bone resorption and bone atrophy after 3 years or longer. Five of these patients had a concomitant ventriculo-peritoneal shunt. Two of them developed collapse of the skull due to bone resorption, and this was considered to have been influenced by the shunt. Epidural empyema occurred postoperatively in five patients (4.5%), and staphylococci were the causative organisms in all five cases. The infections were completely cured by removal of the bone graft, debridement of the wound, and epidural drainage. Cranioplasty following external decompression craniotomy using cryopreserved autogenous bone fragments is a simple procedure, and the materials are inexpensive. Many of our patients who underwent cranioplasty using cryopreserved autogenous bone experienced no serious complications.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1993

[Carotid endarterectomy under cervical epidural anesthesia].

General anesthesia for carotid endarterectomy (CEA) imposes the need for various monitorings of cerebral function during occlusion of the carotid artery. However, there is no ideal method for detecting all the signs of cerebrovascular insufficiency under general anesthesia. We suggest that the patient's neurological state is the best monitor of cerebral function. Therefore, our patients underwent cervical epidural anesthesia (EDA) enabling them to remain conscious while experiencing analgesia of the operated areas throughout the course of the operation. Five patients with cervical internal carotid artery stenosis were operated on under EDA with lidocaine. In all patients, EDA was effective in maintaining an analgesic state in the areas being operated on. It was able to do this either alone, or in combination with a light sedation. Under EDA, although there was no complete suppression of the patient's respiration, blood pressure was elevated beyond 200mmHg in three patients and depressed to 70mmHg in one patient transiently during the operation. But control of abnormal blood pressure was achieved easily by injections of calcium antagonist or ephedrine. When consciousness of two patients deteriorated during the clamping of the internal carotid artery, it completely recovered to its preoperative level after the insertion of an internal shunt. The patient's level of neurological condition became a good guide for predicting the need for an internal shunt during the periods of occlusion of the internal carotid artery. In conclusion, we suggest that EDA which is a safe and useful anesthesia should be employed in many patients who undergo CEA.

Aged↗
PubMed1992

[Surgical outcome of 32 cases in traumatic subdural hygroma].

32 cases of traumatic subdural hygroma (TSH) in adults with surgical treatment were retrospectively investigated by means by clinical features and CT findings. The cases consisted of 29 males and 3 females, aged 41 to 87 years (mean 69). Preparative CT scan of all cases revealed low density area and crescent shape in frontotemporal or frontoparietal subdural space. Half of the cases had bilateral lesions. At operation of TSH, color of subdural fluid collections was more water clear or xanthochromic than bloody. As a results, 22 out of 32 cases (69%) in TSH improved with surgical treatment. Many of effective cases of surgical treatment in TSH had short interval from trauma to operation and light disturbance of consciousness before operation. However, the other intracranial damage will also affect the clinical outcome of TSH, because the majority of cases in this study was accompanied by an intracranial damage including cerebral contusion, subarachnoid hemorrhage or intracranial hemorrhage. Nevertheless, surgical management for TSH was so effective that the operation should be undergone sooner interval from trauma, simultaneously considering the another intracranial lesions except TSH. But then, we experienced 7 cases (22%) of ventricular dilatation and 5 cases (16%) of chronic subdural hematoma in postoperative follow up CT scans. In 5 cases among the former, ventriculoperitonial shunt was done, and in 3 cases among the latter, burr hole evacuation was performed. Therefore, the postoperative course of TSH should require careful observation by CT scan and so on.

Adult↗
PubMed1992

[Recurrent cases of chronic subdural hematoma--its clinical review and serial CT findings].

Eighty-eight cases (114 hematomas) of chronic subdural hematoma (SDH) were treated surgically using irrigation with or without drainage. 13 cases (14.8%), 13 hematomas (11.4%) showed recurrence after the 1st operation. They were compared with non-recurrent cases using clinical reviews and serial CT findings. The result of the study showed that all of the patients in whom recurrence occurred were male and elderly (mean age 70.4 years). Many of these recurrences occurred in cases of bilateral SDH, on the left hematoma side, and at intervals within 7 days from the onset of clinical symptoms after the 1st operation. All recurrent cases were treated surgically using irrigation without drainage. In preoperative CT findings, it was shown that high density areas and small-sized hematomas were detected at a slightly higher rate in recurrent cases than in non recurrent cases. In postoperative CT findings, it was shown that many of the recurrent patients deteriorated during an interval from 2 weeks to 2 months. It was shown that non-recurrent patients had become almost normal by 3 months after the operation. Residual air volume into the subdural space within 7 days in recurrent cases was greater than in non-recurrent cases. Therefore, using irrigation with drainage, planning the operative timing, and reduction of residual air volume into subdural space are proposed as suitable means to avoid recurrence of SDH. Patients of SDH need postoperative follow-up during an interval up to 3 months.

Adult↗
PubMed1984

Indwelling double-balloon shunt for carotid endarterectomy. Technical note.

The authors describe an indwelling intraluminal shunt for carotid endarterectomy. The device is equipped with balloons at both ends to prevent bleeding and to hold the tube in place. The design permits use of a small tube which facilitates insertion, and prevents intimal damage and limitation of exposure of arterial plaque.

Carotid Arteries↗
PubMed1984

Increase of beta-endorphin levels in cerebrospinal fluid but not in plasma in patients with cerebral infarction.

beta-Endorphin was measured in cerebrospinal fluid (CSF) and plasma in patients with cerebral infarction at acute (4 to 48 hours) and chronic (1 month) stages. Only CSF samples obtained in the acute stage showed beta-endorphin values that were statistically higher than those measured in a control population. This finding suggests that infarction at its acute stage gives rise to an increased release of beta-endorphin. Such a mechanism is consistent with the possibility that the reported therapeutic effect of naloxone in cerebral ischemic lesions may result in part from the antagonism of the centrally released endorphin, beta-endorphin.

Adult↗
PubMed1984

[Clinical application of a Biballoon indwelling intraluminal shunt system for carotid endarterectomy].

Clinical applications of newly developed shunt system for carotid endarterectomy were described. The shunt is a silicone tube equipped with balloons at both ends (Biballoon indwelling intraluminal shunt). The blood leak from the gap between a shunt tube and the inner wall of the carotid artery is prevented by inflating balloons after shunt insertion. This shunt system was used in seven cases of cerebral infarction resulted from the carotid stenosis and was proved to be more convenient than other known shunts.

Aged↗
PubMed1981

Relationship between brain tissue pressure gradients and cerebral blood flow distribution studied in circumscribed vasogenic cerebral oedema.

The present experimental study was designed to examine the correlations between brain tissue pressures, pressure gradients and cerebral blood flow distribution associated with circumscribed cerebral vasogenic oedema. Following unilateral hemispheric cryogenic injury in 42 adult cats, brain tissue pressures increased as a function of time. Interhemispheric pressure gradients became most marked one hour after the cryogenic injury (3.9 mm Hg on average), gradually decreasing thereafter. Transtentorial pressure gradients developed within the first hour after the injury, and remained above 10 mm Hg. The dye injected into one carotid system by the "single dye passage" technique was redirected towards the contralateral hemisphere and also towards the subtentorial compartment, as brain tissue pressures increased. The shift in the flow-distribution of dye and blood was more pronounced in the posterior fossa structures. When intracranial tissue pressures exceeded 60 mm Hg almost no dye entered the cranial cavity. This accompanied the marked decrease in cerebral perfusion pressure.

Animals↗