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Biomedical subjects

M Hedberg

Publications and source records attributed to M Hedberg.

59 records · Page 4Linked to original sources
PubMed1969

Effectiveness of acetic acid, betadine, amphyll, polymyxin B, colistin, and gentamicin against Pseudomonas aeruginosa.

The in vitro effectiveness of three germicides and three chemotherapeutic drugs against hospital-isolated strains of Pseudomonas aeruginosa was determined. Solutions of 1% acetic acid, 0.5% Amphyll, and 0.1% Betadine were bactericidal for six strains tested within 15 min at room temperature. Over a 3-year period at the Albany Medical Center Hospital, the percentages of strains of P. aeruginosa susceptible to polymyxin B, colistin, and gentamicin did not increase. During this 3-year period, polymyxin B and colistin were administered at the hospital but gentamicin was not.

Acetates↗
PubMedDate not supplied

Resistance to beta-lactam antibiotics in anaerobic bacteria.

The known mechanisms of beta-lactam resistance in anaerobic bacteria involve production of beta-lactamases, alteration of penicillin-binding proteins, and blocked penetration of beta-lactam antibiotics through bacterial outer membranes. The most important factor in beta-lactam resistance is production of beta-lactamases, which have been found in various Bacteroides, Fusobacterium, and Clostridium species. beta-Lactam resistance in Bacteroides fragilis is commonly mediated by beta-lactamases that are mainly cephalosporinase in character. B. fragilis strains can also produce penicillinases and enzymes inactivating cefoxitin and imipenem. The non-fragilis species of Bacteroides produce beta-lactamases that are mainly penicillinase in character. Penicillinases are also isolated from Fusobacterium nucleatum. Among the clostridia, Clostridium butyricum, Clostridium clostridioforme, and Clostridium ramosum have been shown to produce penicillinases.

Anti-Bacterial Agents↗
PubMedDate not supplied

MR assessment of myelination in infants and children: usefulness of marker sites.

A retrospective study was made of 60 patients, 1 month to 3 years old, to determine the normal progression of white matter myelination on MR imaging. All examinations were performed with a 1.5-T unit, and axial T1- and T2-weighted images were evaluated in each patient. Multiple sites in the cerebral hemisphere and cerebellum were examined in each case for the presence and degree of myelination. The results show that MR imaging is sensitive to the early changes of white matter myelination, and imaging patterns correlate with known patterns from pathologic studies. At the time of birth in a full-term infant the posterior limb of the internal capsule, central corona radiata, and cerebellar peduncles show visible myelination. Myelination in the centrum semiovale then proceeds anteriorly and posteriorly. Both T1- and T2-weighted images show these changes, which are best explained by a decrease in the water content of white matter as myelination progresses. Knowledge of these normal myelination patterns is essential in evaluating MR imaging studies in infants and children and in diagnosing delayed myelination.

Aging↗