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M Hepp

Publications and source records attributed to M Hepp.

15 recordsLinked to original sources
PubMed2005

Randomised, crossover comparison of the single-use SoftSeal and the LMA Unique laryngeal mask airways.

We performed a randomised, crossover, single-blind trial among 168 patients, to compare the single-use SoftSeal and LMA Unique laryngeal mask airways in spontaneously breathing adults. Size-3 and -4 laryngeal mask airways, inserted by experienced anaesthetists, performed equivalently for successful first-time placement (148 (91%) vs 155 (96%) for the SoftSeal and LMA Unique, respectively). The SoftSeal was more often rated as difficult to insert (27 (17%) vs 4 (3%); p < 0.001) and was more likely to show evidence of mucosal trauma after the first insertion (14 (10%) vs 5 (4%); OR 1.3 (95% CI 1.3-11.3); p < 0.05). The fibreoptic view of the larynx was better through the SoftSeal (vocal cords not visible in 27 (17%) vs 44 (27%); p < 0.05) and it more frequently provided a ventilation seal at 20 cmH(2)O (93 (59%) vs 62 (39%); OR 2.15 (CI 1.44-3.21); p < 0.001). In contrast to the LMA Unique(trade mark), its cuff pressure did not increase during nitrous oxide anaesthesia (median (IQR [range]) decrease 3 (- 20-23 [-40-94]) cmH(2)O vs increase of 16 (-2-39 [-54-112]) cmH(2)O; p < 0.01). Both devices were equivalent for the success of first-time insertion and performed satisfactorily clinically. There were some performance differences, but either appears suitable for airway management in spontaneously breathing patients.

Adult↗
PubMed2001

Exploration of xenon as a potential cardiostable sedative: a comparison with propofol after cardiac surgery.

Xenon anaesthesia is thought to have minimal haemodynamic side-effects. It is, however, expensive and requires special delivery systems for economic use. In this randomised cross-over study, we: (i) investigated the haemodynamic profile and recovery characteristics of xenon compared with propofol sedation in postoperative cardiac surgery patients, and (ii) evaluated a fully closed breathing system to minimise xenon consumption. We demonstrated a significantly faster recovery from xenon (3 min 11 s) than propofol sedation (25 min 23 s). Relative to propofol, xenon sedation produced no change in heart rate or mean arterial pressure and there were significantly higher mean values for central venous pressure (10.6 vs. 8.9 mmHg), pulmonary artery occlusion pressure (11.2 vs. 9.5 mmHg), mean pulmonary artery pressure (20.1 vs. 18.3 mmHg) and systemic vascular resistance index (2170 vs. 1896 dyn.s.cm-5.m-2). The haemodynamic profile seen with propofol reflected its known vasodilator effects. This was supported by the almost identical left ventricular stroke work indexes seen with both methods of sedation.

Aged↗
PubMed1999

Effective Rotation-Vibration Parameters for the nu8 and nu4 + nu12 Bands of Ethane.

The jet-cooled spectrum of ethane in the region of the nu8 perpendicular fundamental vibration at 1472 cm-1 was recorded with a Fourier transform spectrometer at 0.01 cm-1 instrumental resolution. About 1150 lines were assigned to 18 subbands of nu8 ranging from K"DeltaK = -9 to +8. About 160 lines were assigned to three subbands (K"DeltaK = 0 to +2) of the nu4 + nu12 combination band near 1481 cm-1. Torsional splittings were observed for the majority of the transitions. A stack-by-stack analysis was performed, resulting in effective rovibrational parameters for the upper states nu8 and nu4 + nu12. A number of perturbations was observed and is discussed. Copyright 1999 Academic Press.

Journal Article↗
PubMed1999

Weak Combination Bands in the 3-µm Region of Ethane.

The infrared spectrum of ethane in the region of the CH-stretching fundamental vibrations, between 2600 and 3300 cm(-1), was recorded with a Bruker IFS120HR Fourier transform spectrometer. Jet-cooled and room-temperature conditions were used at 0.01 and 0.005 cm(-1) instrumental resolution, respectively. Ten weak combination bands were observed and vibrationally assigned, in addition to the three principal bands in the region (nu(5), nu(7), and nu(8) + nu(11) ( parallel component)). A stack-by-stack analysis was performed for five of the combination bands. Their origins were determined as follows: nu(8) + nu(12) ( parallel component) at 2665.1512(30) cm(-1), nu(2) + nu(6) at 2753.326(32) cm(-1), nu(6) + nu(11) at 2844.13069(75) cm(-1), nu(8) + nu(11) ( perpendicular component) at 2930.705(90) cm(-1), and nu(4) + nu(10) at 3255.568(50) cm(-1). Effective rovibrational parameters were obtained for the corresponding upper states. New information was also obtained on the five remaining combination bands. Their approximate origins are: nu(8) + nu(12) ( perpendicular component) at 2660 cm(-1), nu(2) + nu(4) + nu(12) at 2860 cm(-1), nu(4) + 2nu(9) + nu(12) at 3090 cm(-1), 3nu(4) + nu(8) + nu(9) at 3157 cm(-1), and nu(4) + 2nu(8) at 3225 cm(-1). Copyright 1999 Academic Press.

Journal Article↗
PubMed1998

High-Resolution Jet-Cooled Spectroscopy of SF6: The nu2 + nu6 Combination Band of 32SF6 and the nu3 Band of the Rare Isotopomers.

The Fourier transform infrared spectrum of SF6 was recorded in a supersonic expansion jet of an SF6/argon mixture. The SF6:Ar seeding ratio was 2:3. The instrumental bandwidth was 0.005 cm-1. A globar source and an MCT detector were used. A rotational temperature of approximately 30 K was achieved. The nu2 + nu6 combination band of 32SF6 was analyzed using a modified version of the spherical top data system (STDS) programs developed in Dijon. A very good fit was obtained for this band with an rms of 0.0036 cm-1. The effective Hamiltonian was developed up to fourth order for the nu2 + nu6 part, to second order for the nu2 and ground state parts, and to first order for the nu6 part. Five hundred twenty-one transitions were assigned, 40 of them reaching the F2u forbidden sublevel. The positions of the two F1u and F2u sublevels are found to be 991.276 and 989.487 cm-1, respectively. The nu3 band of the 33SF6 and 34SF6 isotopomers were also analyzed. Parameters and simulations are presented. A first detection of the nu3 Q branch of 36SF6 (0.02% natural abundance) is reported. Copyright 1998 Academic Press.

Journal Article↗
PubMed1997

Submillimeter-Wave Absorption Spectroscopy of the Ar-CO Complex: Detection of the van der Waals Bending Vibration

Van der Waals bending rovibrational transitions of the Ar-CO complex were observed between 308 and 383 GHz using submillimeter-wave absorption spectroscopy in a pulsed supersonic jet. The submillimeter radiation was generated by a phase-stabilized backward wave oscillator source. Fourteen transitions of the P and R branch of the bending vibration were measured with an accuracy of about 100 kHz. The frequencies were fitted using effective molecular parameters including the band origin and the rotational constants for the ground state and for the excited bending vibrational state.

Journal Article↗
PubMed1976

[Comparison of value of four immunological methods (AST, ADNase B, AHy, ANADase) by A-streptococcal infections and their significance in the routine diagnostic (author's transl)].

In the sera of approximately 600 patients of all age groups, who were on clinical suspicion of an A-streptococcal infection, AST, ADNase B, AHy and ANADase were determined. The ANADase alone detects 90% of the acute A-streptococcal infections, the AHy and the ADNase B 80% and the ASO 50%. In skin infections superinfected by A-streptococci, the AHy is positive in 85%, the ANADase in 80%, the ADNase B in 75% and the AST in 40% of the cases. The most frequent A-streptococcal infection, Angina tonsillaris, is determined in the best manner possible through the combination ADNase B + ANADase + AHy. According to the statistical evaluation, the ADNase B and the ANADase are the most reliable tests. The age group of the 4 to 15 year-olds reaches for ASO, ADNase B and AHy a percentage of highly increased titers twice as high in comparison with the adult group. In no case does one test determine 100% of the collective; therefore, a combination of several antibody reactions is desirable for the diagnosis. Increased titers should be checked every four weeks, also normal titers with patients, who continue on the clinical suspicion of having an A-streptococcal infection, because their blood sample may have been taken before the immune reaction occurred.

Adolescent↗