PubMed Health⌕ Search

Biomedical subjects

M Hilt

Publications and source records attributed to M Hilt.

8 recordsLinked to original sources

Stripe-hexagon competition in forced pattern-forming systems with broken up-down symmetry.

We investigate the response of two-dimensional pattern-forming systems with a broken up-down symmetry, such as chemical reactions, to spatially resonant forcing and propose related experiments. The nonlinear behavior immediately above threshold is analyzed in terms of amplitude equations suggested for a 1:2 and 1:1 ratio between the wavelength of the spatial periodic forcing and the wavelength of the pattern of the respective system. Both sets of coupled amplitude equations are derived by a perturbative method from the Lengyel-Epstein model describing a chemical reaction showing Turing patterns, which gives us the opportunity to relate the generic response scenarios to a specific pattern-forming system. The nonlinear competition between stripe patterns and distorted hexagons is explored and their range of existence, stability, and coexistence is determined. Whereas without modulations hexagonal patterns are always preferred near onset of pattern formation, single-mode solutions (stripes) are favored close to threshold for modulation amplitudes beyond some critical value. Hence distorted hexagons only occur in a finite range of the control parameter and their interval of existence shrinks to zero with increasing values of the modulation amplitude. Furthermore, depending on the modulation amplitude, the transition between stripes and distorted hexagons is either subcritical or supercritical.

Journal Article↗

The new topical steroid ciclesonide is effective in the treatment of allergic rhinitis.

A randomized, placebo-controlled, double-blind crossover study was performed to investigate the efficacy of ciclesonide nasal spray in allergic rhinitis at the dose level of 200 micrograms per nostril. Twenty-four subjects (13 males, 11 females; median age: 28 years) with a history of allergic rhinitis but free of symptoms at screening entered the study. Ciclesonide and placebo were given for 7 days each with a washout period of at least 14 days in between. In both treatment periods, controlled intranasal allergen provocation with pollen extracts was performed on the 2 days before start of treatment (days -2 and -1) and on all treatment days (days 1 to 7) about 2 hours after administration of the study medication. At 5 and 30 minutes after each allergen provocation, rhinal airflow was measured by anterior rhinomanometry, and the subjective symptoms of obstruction, itching, and rhinorrhea were assessed by means of a standardized visual analog scale. Rhinal airflow improved significantly from day 5, while the subjective symptom of obstruction improved from day 2. Itching and rhinorrhea also improved significantly. The local and systemic tolerability of ciclesonide nasal spray was excellent. The results of this study clearly indicate that the new topical steroid ciclesonide is effective in the treatment of allergic rhinitis without producing local or systemic side effects.

Administration, Intranasal↗

Epidemiology of gambling and depression in an adult sample.

As a relationship has been reported between pathological gambling and depression, the objective of this study was to explore whether there was a relationship between gambling and depression in a sample of 400 adults. No relationship was found.

Adolescent↗

[Sideroblastic anemia].

Explore the source record for details and available documents.

Anemia, Sideroblastic↗