Biomedical subjects

M Hiltgen

Publications and source records attributed to M Hiltgen.

At least 37 records · Page 2Linked to original sources

PubMed1986

[Circumflex artery originating from the right anterior sinus of Valsalva: benign anomaly or a factor in myocardial ischemia? Apropos of 2 cases].

The abnormal formation of the circumflex artery from the right anterior sinus of Valsalva is generally considered benign and without any particular ischemic risk. Two cases are reported of myocardial ischemia in the region of the abnormal artery. In both cases an unstable angina was associated with objective criteria (electrocardiographic and isotopic) of myocardial ischemia. In one case the circumflex artery presented marked proximal stenosis compatible with the development of accelerated atherosclerosis. In the other case the circumflex artery was free of any stenosis and the ischemic manifestations observed seem to be due to the abnormal origin of the vessel only. Certain cases of the circumflex artery anomaly can, therefore, be complicated by myocardial ischemia, and the benign nature of the anomaly needs to be re-examined.

Coronary Disease↗

PubMed1985

Atrial septal aneurysm--a potential cause of systemic embolism. An echocardiographic study.

Atrial septal aneurysm is an uncommon condition. Between 1981 and 1984 10 cases of atrial septal aneurysm were diagnosed by real time cross sectional echocardiography performed in 4840 patients. The aneurysm was associated either with mitral valve prolapse (three patients) or with atrial septal defect (three patients) or occurred in isolation (four patients, two of whom had had a previous embolic event leading to the diagnosis of atrial septal aneurysm by cross sectional echocardiography). During cross sectional echocardiography the aneurysm appeared as a localised bulging of the interatrial septum, which was best seen in the subcostal four chamber view and in the parasternal short axis view at the level of the aortic root. The aneurysm either protruded into only the right atrium (five patients) or moved backwards and forwards between the right and the left atria during the cardiac cycle (five patients). This motion pattern might be related to changes in the interatrial pressure gradient. The two patients who had had a systemic embolism were given anticoagulant treatment, but none underwent surgery. It is concluded that the true prevalence of atrial septal aneurysm might have been underestimated before the routine use of cross sectional echocardiography, that cross sectional echocardiography enables definitive diagnosis of this condition by a non-invasive technique, and that an atrial septal aneurysm should be suspected and looked for by cross sectional echocardiography after an unexplained systemic embolism.

Adolescent↗

PubMed1975

[Correlations of the coronary arteriography with clinical data and electrocardigraphy].

The correlation between coronary arteriograms, E.C.G. and clinical data of two thousand patients was studied. In those suffering from angina on effort there was a significant correlation between the intensity and frequency of the anginal pain and the extension of the lesion in one, two or in all three main coronary arteries. In those suffering from angina at rest only one of the coronaires was usually affected. The greatest degree of lesions was found in patients with prolonged and spontaneous crises of anginal pain. In those patients suffering from progressive angina and intermediate coronary syndrome the lesions were spread totwo or all three coronaries. E.C.G. abnormalities were always correlated with significant lesions of the coronary vessels while normal or "atypical" E.C.G. were usually correlated with only slight lesions in these vessels or with normal vessels. In a few cases however angina and myocardial infarction were present in spite of apparently normal coronaries. The reason for this discrepancy is still under investigation: myocardial metabolism and coronary flow abnormalities could in part explain these finding.

Angina Pectoris↗

PubMed1974