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Biomedical subjects

M Hioki

Publications and source records attributed to M Hioki.

At least 19 recordsLinked to original sources
PubMed1992

Stereotactic radiosurgery using a linear accelerator.

A basic and clinical study of radiosurgery using the linear accelerator (Linac) system for unremovable deep-seated brain tumors is reported. A Komai stereotactic ring was used to locate the target coordinates. The patient was laid on the Linac treatment table and held in the head fixation system. Irradiation was given in five positions. The dose profile by film dosimetry and Rando phantom was satisfactory. Seventeen tumors in 14 patients were treated. Clinical or histological diagnoses were nine metastases, one benign and two malignant gliomas, one meningioma, and one craniopharyngioma. Tumor sizes were between 8 and 30 mm. Doses were between 12 and 30 Gy. Computed tomographic evaluation after 3 months of 12 tumors in 11 survivors showed one complete remission, three partial remission, six no change, and two partial deterioration. For progressive tumors, Linac radiosurgery results are excellent.

Adult↗
PubMed1992

[Combined superior-transseptal approach to the mitral valve].

We report a technique to improve exposure of the mitral valve apparatus. This technique that combines superior left atriotomy and interatrial septotomy can be helpful in patients with a small left atrium and reoperation. It has been used effectively in five patients and potential complication with this procedure has not occurred. The operative technique and indication are discussed in this paper.

Adult↗
PubMed1991

[Clinical experience of intramediastinal injection therapy via mediastinoscope for lung cancer].

As local treatments other than surgery, radiation therapy, bronchial artery infusion and intrabronchial injection of anti-cancer drugs have generally been administered to inoperative lung cancer cases. Together with these local therapies, we experienced six cases of intramediastinal injection. Indication of this therapy has been fundamentally limited to the inoperative cases in which patient performance status has deteriorated. Histologically, three cases were squamous cell carcinoma and three cases were adenocarcinoma. Injection therapy was effective in four cases where we noted alleviation of atelectasis and obstructive pneumonia brought on by the tumor, and a tendency of the tumor and swelling lymph nodes to be reduced. No side effects nor complications were evidenced. This therapy is characterized by a wider injection area in which intrabronchial injection is incapable of reaching the upper mediastinum, the bifurcation and the upper side of the hilus. The results suggest that this therapy should be used alone or together with other local therapies and prior to operation.

Adenocarcinoma↗
PubMed1991

[A successful case report of ruptured abdominal aortic aneurysm with isolated left-sided inferior vena cava].

A 68-year-old man was admitted to our hospital because of shock. CT scan revealed ruptured abdominal aortic aneurysm (AAA) with isolated left-sided inferior vena cava (L-IVC). After emergent laparotomy, maintaining blood pressure stable, we clamped the aorta at the level of the supra-celiac region. An AAA (8.5cm in diameter) leaking from the posterior wall with a retroperitoneal hematoma was found, and L-IVC pressed by AAA was identified. The AAA was dissected with caution so as not to injure L-IVC and replaced with a woven Dacron bifurcated graft. The postoperative course was uneventful. The embryonic development and clinical significance of this rare anomaly are discussed. This is the first successful case in the Japanese literature by our survey.

Aged↗
PubMed1991

[Changes in high-energy phosphates in the myocardium before and after ischemia].

Assessment of the level of high-energy phosphates in the myocardium before, during and after ischemia was performed in 19 consecutive patients who underwent cardiac operation. The following results were obtained. 1) The levels of total nucleotides (ATP, ADP, AMP, CP) determined before, during and after aortic cross clamp were 14.94 +/- 4.12, 5.59 +/- 2.16 and 3.58 +/- 1.14 micrograms/mg. protein in the right atrial appendage. Those in the left ventricular myocardium were 18.22 +/- 4.90, 6.99 +/- 1.52 and 4.35 +/- 1.06 micrograms/mg. protein. The latter levels were higher than the former. 2) Rapidly decreasing after aortic cross clamp, the nucleotides dropped to 37-38% of preischemic level during aortic cross clamp and to 23% of preischemic level 30 minutes after reperfusion. At the termination of extracorporeal circulation, when circulatory dynamics stabilized, the nucleotides were only recovered to 50-53% of preischemic level. 3) Negative correlation was observed between the length of aortic cross clamp time and the content of nucleotides in the atrial muscle. (p less than 0.05) 4) Fluctuations in the nucleotide level indicated that the current method of myocardial protection using GIK solution produced unsatisfactory recover from ischemic damage and reperfusion injury.

Adenine Nucleotides↗
PubMed1990

[Measurement of myocardial temperature with infrared radio-thermometer in cardiovascular surgery].

We used an infrared radio-thermometer for measurement of myocardial temperature in cardiovascular surgery and a high correlation was observed when it was compared with a contact thermometer. This thermometer is characterized by the fact that it can be used in a non-contact remote-control manner either in a moving body or in a dark location. It is expected that this thermometer will be increasingly used in the clinical area in the future.

Body Temperature↗
PubMed1989

[A case of primary rhabdomyosarcoma of the right ventricle].

A 32-year-old man was admitted to our hospital suffering from cough and bloody sputum. After the preoperative examination, the most suspected diagnosis was either a cardiac myxoma or a pulmonary embolism. At operation, the cavity of main pulmonary trunk was occupied with a tumor growing through the stalk from the outflow tract of right ventricle. The invasive tumor was not completely removed from the pulmonary tract. Rhabdomyosarcoma originating from the right ventricle was confirmed histologically. The patient died on the 199th postoperative day. A necropsy was not conducted. Diagnosis, operative indication and chemotherapy of cardiac rhabdomyosarcoma are discussed in this paper.

Adult↗
PubMed1989

[Surgical treatment of metastatic lung cancer arising from the colon and rectum].

Ten cases of surgically resected pulmonary metastases arising from colorectal cancer were analyzed. Five year survival rate of these patients was 14%. Only one patient survived more than five years, whose primary and metastatic lesions were not so progressive without lymph node metastasis. The rate of regional lymph node metastasis was 25% and the patients with positive nodes died or had recurrence within 2 years. Serum CEA level was useful as a tumor marker and high-level of serum CEA after operation suggested remnant disease.

Aged↗
PubMed1989

[Surgical correction for partial anomalous pulmonary venous connection with intact atrial septum without using extracorporeal circulation].

A 13-year-old boy with partial anomalous pulmonary venous connection (PAPVC) having an intact atrial septum (IAS) is reported. He had open heart surgery 3 years ago at another hospital, but the cardiac septum was intact and PDA was ligated. After his discharge, cardiomegaly and increased right pulmonary vasculature were seen in chest roentgenograms. Our cardiac catheterization data and pulmonary angiograms showed that he had a PAPVC with IAS. Surgical correction was accomplished by utilizing a polytetrafluoroethylene graft with external ring support and interposing it between the right upper pulmonary vein and the left atrium during thoracotomy without the need for extracorporeal circulation. The postoperative course was uneventful and he was discharged on the 14th postoperative day. At 3 months postoperatively, radionuclide studies demonstrated no evidence of pulmonary congestion or graft obstruction. To our knowledge, this is the first clinical report of prosthetic replacement of the pulmonary venous pathway with graft patency demonstrated postoperatively.

Adolescent↗