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M Huq

Publications and source records attributed to M Huq.

13 recordsLinked to original sources

Indoor air quality for poor families: new evidence from Bangladesh.

Poor households in Bangladesh depend heavily on wood, dung and other biomass fuels for cooking. This paper provides a detailed analysis of the implications for indoor air pollution (IAP), drawing on new 24-h monitoring data for respirable airborne particulates (PM10). A stratified sample of 236 households was selected in Dhaka and Narayanganj, with a particular focus on fuel use, cooking locations, structural materials, ventilation practices, and other potential determinants of exposure to IAP. At each household, PM10 concentrations in the kitchen and living room were monitored for a 24-h period during December, 2003-February, 2004. Concentrations of 300 microg/m3 or greater are common in our sample, implying widespread exposure to a serious health hazard. A regression analysis for these 236 households was then conducted to explore the relationships between PM10 concentrations, fuel choices and a large set of variables that describe household cooking and ventilation practices, structure characteristics and building materials. As expected, our econometric results indicate that fuel choice significantly affects indoor pollution levels: natural gas and kerosene are significantly cleaner than biomass fuels. However, household-specific factors apparently matter more than fuel choice in determining PM10 concentrations. In some biomass-burning households, concentrations are scarcely higher than in households that use natural gas. Our results suggest that cross-household variation is strongly affected by structural arrangements: cooking locations, construction materials, and ventilation practices. A large variation in PM10 was also found during the 24-h cycle within households. For example, within the 'dirtiest' firewood-using household in our sample, readings over the 24-h cycle vary from 68 to 4864 microg/m3. Such variation occurs because houses can recycle air very quickly in Bangladesh. After the midday meal, when ventilation is common, air quality in many houses goes from very dirty to reasonably clean within an hour. Rapid change also occurs within households: diffusion of pollution from kitchens to living areas is nearly instantaneous in many cases, regardless of internal space configuration, and living-area concentrations are almost always in the same range as kitchen concentrations. By implication, exposure to dangerous indoor pollution levels is not confined to cooking areas. To assess the broader implications for poor Bangladeshi households, we extrapolate our regression results to representative 600 household samples from rural, peri-urban and urban areas in six regions: Rangpur in the north-west, Sylhet in the north-east, Rajshahi and Jessore in the west, Faridpur in the center, and Cox's Bazar in the south-east. Our results indicate great geographic variation, even for households in the same per capita income group. This variation reflects local differences in fuel use and, more significantly, construction practices that affect ventilation. For households with per capita income <US Dollars 1.00/day, rural PM10 concentrations vary from 410 microg/m3 in Cox's Bazar to 202 microg/m3 in Faridpur. In urban areas, concentrations for such households differ by almost 100 microg/m3 between the highest areas, Jessore and Rajshahi, and the lowest, Sylhet. Practical Implications Our analysis suggests that poor families may not have to wait for clean fuels or clean stoves to enjoy significantly cleaner air. Within our sample household population, some arrangements are already producing relatively clean conditions, even when 'dirty' biomass fuels are used, such as simple changes in ventilation characteristics of housing (construction materials, space configurations, cooking locations and placement of doors and windows) and ventilation behavior (keeping doors and windows open after cooking). As these arrangements are already within the means of poor families, the scope for cost-effective improvements may be larger than is commonly believed.

Air Pollutants↗

Superparallel holographic correlator for ultrafast database searches.

We describe a superparallel holographic optical correlator that performs two-dimensional spatial and angular multiplexing simultaneously. The key step in this architecture is the use of a holographic multiplexer to split a query image into many copies before it applies them to the holographic database. A holographic demultiplexer, in conjunction with an aperture, is used to identify the location and the angle of the brightest correlation peak. This architecture uses only O(square root of N) detector elements to search through N unsorted images in a single query. We demonstrate the basic features of this architecture, using three spatial locations with eight angle-multiplexed images in each location.

Journal Article↗

Grazing collisions of black holes via the excision of singularities.

We present the first simulations of non-head-on (grazing) collisions of binary black holes in which the singularities are excised from the simulation. Initially equal mass m black holes (spinning or not) are separated by approximately 10m and with impact parameter approximately 2m. Evolutions to t approximately 35m are obtained where two separate horizons are present for t approximately 3.8m; then a single enveloping horizon forms indicating that the holes merged. Apparent horizon area estimates suggest gravitational radiation of about 2%-3% of the total mass. The evolutions end after a moderate amount of time because of instabilities.

Journal Article↗

A Huntington disease-like neurodegenerative disorder maps to chromosome 20p.

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor disturbance, cognitive loss, and psychiatric manifestations. The disease is associated with a CAG trinucleotide-repeat expansion in the Huntington gene (IT15) on chromosome 4p16.3. One family with a history of HD was referred to us initially for predictive testing using linkage analysis. However, the chromosome 4p region was completely excluded by polymorphic markers, and later no CAG-repeat expansion in the HD gene was detected. To map the disease trait segregating in this family, whole-genome screening with highly polymorphic dinucleotide-, trinucleotide-, and tetranucleotide-repeat DNA markers was performed. A positive LOD score of 3.01 was obtained for the marker D20S482 on chromosome 20p, by two-point LOD-score analysis with the MLINK program. Haplotype analysis indicated that the gene responsible for the disease is likely located in a 2.7-cM region between the markers D20S193 and D20S895. Candidate genes from the mapping region were screened for mutations.

Adult↗

Role of testicular fine-needle aspiration biopsy in the evaluation of male infertility: cytologic and histologic correlation.

A series of testicular fine-needle aspiration biopsy specimens from 272 infertile men with azoospermia were reviewed and categorized according to morphologic patterns. These included active spermatogenesis, 14 (5%); hypospermatogenesis, 106 (39%); Sertoli cells only, 70 (26%); atrophic pattern, 52 (19%); and maturation arrest, 1 (0.36%). In 29 cases (11%) the amount of material was insufficient for evaluation. The histologic and cytologic findings in 52 cases showing spermatogenesis correlated very well in 52 cases for which open testicular biopsy specimens were also available. These findings indicate that fine-needle aspiration biopsy of the testis is a reliable and useful technique for the investigation of patients with azospermia.

Adult↗

Fine-needle aspiration biopsy of papillary thyroid carcinoma: cytologic, histologic, and ultrastructural correlations.

Aspiration smears from a series of 21 papillary thyroid carcinomas were studied and a number of morphologic features correlated with the histologic and ultrastructural patterns. These included types of papillary structures, metaplastic cells, grooved and lobulated nuclei, optically clear nuclei, intranuclear inclusions, and macrophages. Generally there was a close correlation between histologic and cytologic findings. The numbers of macrophages and metaplastic cells appeared to be exaggerated in aspiration smears as compared with those seen on histologic sections. Optically clear nuclei were not seen on the air-dried cytologic smears. Grooved nuclei were somewhat difficult to recognize in the aspiration smears, although lobulated nuclei were identified easily. We consider the latter to be a significant feature in the diagnosis of papillary carcinoma. Ultrastructurally grooved nuclei showed a deep linear indentation of the nuclear membranes. Lobulated nuclei were characterized by multiple indentations that divided the nucleus into several lobules.

Biopsy↗

Fine-needle aspiration biopsy of seminoma and dysgerminoma: cytologic, histologic, and electron microscopic correlations.

Cytomorphologic features in a series of fine-needle aspiration biopsies from eight patients with seminoma or dysgerminoma were reviewed, and the findings were further correlated with histopathologic and ultrastructural appearances. Three cell types were encountered. Type I was least differentiated and least frequent. Type II was most frequent and had well-developed cytoplasm rich in organelles. Type III was similar to type II but also contained abundant cytoplasmic glycogen. In cytology smears, type III cells contained large punched-out cytoplasmic vacuoles corresponding to the areas of glycogen deposition. The background contained a variable mixture of inflammatory cells including lymphocytes, plasma cells, epithelioid cells, and epithelioid granulomas. The significance of these findings in the diagnosis of seminoma or dysgerminoma and the distinction from other germ-cell and non-germ-cell tumors is briefly discussed.

Adolescent↗

Fine-needle biopsy: comparison of cellular yield with and without aspiration.

Fine-needle biopsies with and without aspiration were performed on 103 lesions, and the cellular yields obtained by the two techniques were compared. A scoring system was devised by which the amount of material obtained in each needle stick was estimated. The mean score/stick for fine-needle biopsy with aspiration was 2.7; for biopsy without aspiration, it was 2.9. The results of this study indicate that there is no significant difference in the amount of cellular material obtained by the two techniques. It is concluded that needle biopsy without aspiration may be performed routinely with good results.

Biopsy, Needle↗