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Biomedical subjects

M I Bernshteĭn

Publications and source records attributed to M I Bernshteĭn.

At least 19 recordsLinked to original sources

[Complex radionuclide diagnosis of phlebothromboses in patients with cancer of the corpus uteri].

The data on a complex radionuclide examination of veins of lower extremities carried out in the course of diagnosis of phlebothrombosis in cases of cancer of cervix uteri are presented. Radionuclide measurements with 125I-fibrinogen were carried out for diagnosis of venous thrombosis in lower extremities in 38 surgical patients and the signs of thrombosis were identified in 8 cases (21.1%). Phleboscintigraphy using 99mTc-labeled MAA was performed in 18 patients in order to preoperatively evaluate the status of deep veins of the lower extremities. In cases of symptoms of venous disease, phleboscintigrams showed such pathological features as construction or dilation of veins, foci of accumulated 99mTc-labeled MAA and collateral blood flow.

Female↗

[Effect of anesthesia on a neoplastic process in an experiment].

The modifying influence of anaestesia on tumourigenic process (its stimulative or inhibitory effect upon tumour and metastasis growth) was established. It may occur indirectly, i.e. through endocrine link of the host-tumour system, and due to cytostatic effect of the anaesthetic drug (fluothane in particular).

Anesthesia, Inhalation↗

[Effect of surgical and combined treatments on the state of the blood coagulating system in cancer of the corpus uteri].

The study of blood coagulability in the coarse of combination (77 cases) and surgical (17 cases) treatment of endometrial carcinoma showed that surgery is followed by an increased plasma tolerance to heparin, a raised fibrinogen level and a lowered fibrinolytic activity. Therefore, surgery promotes blood coagulability, thus increasing the risk of thromboembolic complications in endometrial cancer patients in postoperative period. Preoperative hormonotherapy seems to contribute to this risk since it increases blood coagulability and delays its normalization in postoperative period.

17 alpha-Hydroxyprogesterone Caproate↗

[Comparative evaluation of the adrenal functional state in the surgical and combined treatment of lung cancer].

The functional state of the adrenal glands diring surgical and combination treatment was examined in 38 radically operated patients with pulmonary cancer. Irradiation of lung cancer patients was found to stimulate the adrenal glands activity followed by reduction of their potentalities, manifested in a less marked increase of the catecholamines level and decreased 11-OCS level in blood during surgical treatment.

11-Hydroxycorticosteroids↗

[Transplantability and growth of sarcoma 37 under a ganglionic blockade].

The inoculation of sarcoma-37 against the background of the ganglionary blockade, provided by the intraperitoneal injection of 1 ml of pentamine, is not associated with its less take rate, but there is a manifest suppression of the tumor growth during the period up to 63 days. A preliminary ganglionary blockade completely eliminates the stimulating effect of a trauma on the tumor growth.

Amputation, Surgical↗

[Use of narcotic analgesics for the postoperative anesthetization of oncological patients].

The authors have studied the efficacy of narcotic analgesics in the postoperative period by a complex method, including a psychosomatic questionnaire, spirography, volumetry, analgesiometry, as well as a examination of the cardiovascular system and acid-base balance. Under examination were 183 patients subjected to surgery for tumors of the female genitalia and rectum (a lower laparatomy). The analgesic activity of promedol, omnopone, morphine and polyvinly-morpholidone in routine doses was estimated. It was noted that, if not contraindicated, narcotic analgesics may be successfully employed for analgesia in the early postoperative period.

Adult↗

[Results of treating the late complications of patients radically operated on for rectal cancer].

Based on the study of the causes of rehospitalization of 323 patients. Previously operated upon for rectal cancer, it was found that 91 patients developed late postoperative complications, 96 - recurrences, 45 - distant metastases and 51 - metachronous tumors. Among surgical complications colostome strictures in the anal region (37), mucosa prolapse (26) and paracolonic fistulas (23) were most frequently observed. The analysis of treatment for tumor recurrences (96) and distant metastases (45) indicated that surgical excision seems to be mostly effective as a radical procedure. The effect of electrocoagulation in recurrences is somewhate inferior to surgery but still it is appreciable enough. The use of irradiation, chemotherapy, palliative operations fails to produce any appreciable effect on patients' lifeterms.

Humans↗

[Hemodynamic indices and the volume of circulating blood in the surgical treatment of cancer of the esophagus and cardial portion of the stomach].

The authors report the data on changes in some indices of the hemodynamics, red blood, total blood serum protein, the circulatory volume and amount of the operative blood loss in radical surgical treatment of patients with cancer of the esophagus and cardia. Depending on the kind of anesthesia all patients were subdivided into three groups: in the first group ether-nitrous oxide-oxygen endotracheal narcosis was employed, in the second-fluothane-nitrous oxide-oxygen endotracheal narcosis and in the third-neuroleptanalgesia.

Adult↗

[Changes of peripheral blood flow in patients with cancer of the lungs, esophagus and cardia under the effect of anesthesia and surgery].

The authors report the data on changes in peripheral circulation, depending on the kind of anesthesia, the amount of operative blood loss, alterations in circulating blood volume and localization of tumor in patients with cancer of the lung, esophagus and cardia. Totally, 35 patients (15--lung cancer, 10--esophageal cancer, 10--cancer of the cardia) were explored. In 25 cases fluothane was used as the main anesthetic, in 10--neuroleptanalgesia. The state of peripheral circulation was estimated by the period semielimination of radioactive xenon-133 from the muscle depot. It was found that alterations in peripheral circulation were not dependent on tumor localization, the use of fluothane and neuroleptanalgesia is associated with similar changes in peripheral blood flow and, finely, an increased loss of blood results in more pronounced alterations in peripheral circulation.

Aged↗

[Hemipelvectomy and its anesthesiological management].

Based on the study of an operative course, anesthesia and immediate postoperative period in 63 patients subjected to hemipelvectomy, it is demonstrated that the danger of early complications in these cases, at present, is not great relatively, and such operations can and must be performed, if indicated. Moreover, hemipelvectomy produces a number of specific changes in the organism that should be taken into consideration in conduction of anesthesia and corrective therapy postoperatively. Ganglionary blockade seems to be an obligatory constituent of anesthesiological provision in hemipelvectomy.

Adolescent↗