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Biomedical subjects

M I Boechat

Publications and source records attributed to M I Boechat.

68 records · Page 4Linked to original sources
PubMed1985

Interventional radiology in infants and children: clinical and technical aspects.

The authors performed 53 extravascular interventional procedures in 47 pediatric patients between July 1981 and September 1983. Except for transhepatic cholangiography in patients without intrahepatic biliary dilatation, the success rate was high. There were few complications, and none that were life-threatening or required surgery. More than 90% of procedures were performed without general anesthesia. Factors essential to safe and successful intervention in infants, children, and adolescents, in the authors' opinion, include (a) active involvement by the radiologist, (b) guidance by real-time imaging, (c) careful matching of needles, catheters, and guide wires to patient size, and (d) adequate sedation and analgesia.

Abdomen↗
PubMed1985

Computed tomography in stage III neuroblastoma.

This multicenter study was designed to determine if CT can assess operability in stage III neuroblastoma. Nineteen children (11 boys, eight girls), aged 2-51 months, considered to have, by conventional clinical and radiographic examinations, localized neuroblastoma that crossed the midline were examined by CT. After intravenous and oral contrast media enhancements, CT was able to show the relation of the tumor to the adjacent vital vessels: aorta, celiac axis, and superior mesenteric artery. In all 15 patients, tumors that encased the aorta or its major branches were unresectable. However, three of four tumors crossing the midline but not coming into contact with the aorta or adherent only to one side of the vessel could be resected. Because surgery currently plays the major role in the treatment of neuroblastoma, the relation of the tumor to the aorta and great vessels is a more reliable and important factor in predicting the outcome of these children than the extension and location of the tumor with reference to the midline. CT after intravenous contrast enhancement can establish this relation and assess resectability.

Abdominal Neoplasms↗
PubMed1984

High-resolution spinal sonography in infants.

High-resolution, real-time sonography of the spine revealed significant anatomic details in 29 infants, including nine with congenital malformations. Transverse sections were most useful for detecting osteochondral anomalies and for evaluating the symmetry of the spinal column and its soft-tissue contents. Longitudinal sections augmented the transverse sections and provided the most detailed anatomy of the cord and spinal arteries. A normal screening sonographic examination obviates ionizing radiation and invasive procedures, while an abnormal study implies the need for further, complementary diagnostic investigations.

Humans↗
PubMed1983

Megacystis-microcolon-intestinal hypoperistalsis syndrome in a newborn girl whose brother had prune belly syndrome: common pathogenesis?

A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with prune belly syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal remnants and familial incidence. MMIHS and PBS may be manifestations of the same underlying process.

Abnormalities, Multiple↗
PubMed1978

Diverticula of the bladder in children.

Diverticula of the bladder in infants and children are common and occur when vesical mucosa protrudes through a congenital defect in the muscle wall. Most are primary. Diverticula secondary to obstruction or neurogenic dysfunction are not as common as was once thought. The majority of diverticula are asymptomatic but they can cause vesico-ureteral reflux, obstruction or residual urine. Diverticula also occur after bladder surgery and in association with some syndromes. Voiding cystourethrography is the most reliable method for detection.

Abnormalities, Multiple↗
PubMedDate not supplied

MR imaging of bone marrow in children.

The magnetic resonance (MR) images of the knees and hips of children with systemic diseases involving bone marrow were correlated with their marrow histology and compared with the images of asymptomatic normal children. In normal children the intensity of the MR signal from the bone marrow of the knees and hips was uniform throughout the metaphyses and diaphyses. In contradistinction the MR signal was uniformly diminished for the hypercellular marrow of patients with sickle cell anemia, was similar to normal for the hypocellular hyperfatty marrow of untreated aplastic anemia, and was nonuniform and patchy for leukemic marrow.

Adolescent↗
PubMedDate not supplied

MR imaging in Drash syndrome.

Drash syndrome is a disorder of the genitourinary ridge differentiation and includes abnormal genital development, nephropathy, and a predisposition to develop Wilms tumor. In three patients with Drash syndrome, magnetic resonance was correlated with ultrasound, CT, and surgical findings. Two patients with glomerulonephritis had enlarged kidneys, loss of corticomedullary differentiation, and overall decrease in signal intensity on T1-weighted sequences. Two large Wilms tumors were identified, but a small 1 cm nephroblastoma was not recognized. Anomalies associated with ambiguous genitalia, such as absent uterus, were also correctly diagnosed.

Disorders of Sex Development↗
PubMedDate not supplied

The effect of limping on vertebral bone density: a study of children with tarsal coalition.

To determine whether limping is associated with decreased bone mineralization, the trabecular and integral bone densities (BDs) of 18 Caucasian children exhibiting computed tomographic evidence of tarsal coalition (14 boys, 4 girls, aged 9 years, 5 months to 16 years, 3 months) were compared with those of an age- and sex-matched control group. Patients with tarsal coalition had significantly lower trabecular (p less than 0.05) and integral (p less than 0.05) BD than controls. Trabecular spinal density was approximately 17% lower on the average in patients with tarsal coalition. Among the limping patients, neither the duration of symptoms nor bilaterality was associated with decreased BD. The findings suggest that painful tarsal coalition may decrease vertebral bone mass and predispose to spinal osteoporosis.

Adolescent↗
PubMedDate not supplied

Five years experience with recombinant human growth hormone treatment of children with chronic renal failure.

11 males, aged 2.5-16.3 years (6.8 +/- 4.1) with growth retardation (Standard Deviation Score--SDS > -2.00) consequent to chronic renal failure (CRF) received recombinant human growth hormone (rhGH) for 18 to 60 mo (40.9 +/- 15.4). Growth velocity (GV) increased from 5.4 +/- 2.2 for the year prior to rhGH to 8.9 +/- 1.6 (p = 0.00001), 7.4 +/- 1.7 (p < 0.03), 7.6 +/- 1.6 (p < 0.006), 6.5 +/- 1.0 (p < 0.05) and 7.5 +/- 1.3 (p = NS) cm/yr following 12, 24, 36, 48 and 60 mo respectively of treatment. The mean SDS for height decreased from -3.21 at baseline to -0.85 at 60 mo (p = 0.0004); 7 of 8 pts treated for > 36 mo had a SDS more positive than -2.00; 3 reached the 50th percentile on the growth curve. In 2 patients the dosage was doubled to achieve the increase in GV; in one patient it took 5 yrs to reach a SDS more positive than -2.00. A significant increase in weight gain and mid-arm muscle circumference over baseline values were indicative of the anabolic effect of rhGH. The mean increase in bone age was similar to the increase in chronologic age; the delta bone age-delta height age was not significant indicating no loss of growth potential following rhGH. Although 3 patients required the initiation of dialysis following rhGH treatment, the mean calculated creatinine clearance did not decrease significantly. No significant adverse effects were noted. These data indicate that long-term rhGH treatment is effective in improving the GV of children with CRF and facilitating catch-up growth without loss of growth potential.

Adolescent↗
PubMedDate not supplied

The significance of increased echogenicity in the detection and differentiation of pediatric disease.

Increased renal echogenicity, by ultrasonography, is seen in various pathological conditions. Correlation of renal size with the pattern and distribution of the increased echogenicity, and the patient's age and clinical data will limit the differential diagnosis and suggest the appropriate radiographic follow-up studies, obviating the need for unnecessary procedures.

Burkitt Lymphoma↗