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Biomedical subjects

M I Liddington

Publications and source records attributed to M I Liddington.

6 recordsLinked to original sources

Reconstruction of skull base and dura using rectus abdominis muscle combined with a vascularised fascial perforator flap.

The goal of reconstruction of the skull base is to repair dural defects with a watertight seal and separate it from the nasopharynx and the exterior environment with well vascularised tissue. This prevents cerebro-spinal fluid leakage and secondary contamination leading to the potentially life threatening complications of meningitis or extradural abscess. Following large composite resections, traditional techniques to repair the dura involve the use of an autologous fascial graft or a pericranial flap, whilst a regional pedicled or free muscle flap is used to close the dead space defect. We describe a technique performed in two cases, whereby a single flap, the rectus abdominis muscle free flap, can be used to provide vascularised reconstruction both of the dura and the skull base. The anterior rectus sheath, islanded on a single perforator vessel, is used as a vascularised layer to reconstruct dura, whilst the supporting rectus abdominis muscle provides bulk to obliterate dead space. We show that this flap is suitable for reconstruction even in the presence of chronic infection. Advantages of a vascularised reconstruction are the rapid healing of the wound, even after radiotherapy, the delivery of systemic antibiotics to the site of the operation, and that it may allow early postoperative radiotherapy to be planned.

Adult↗

Timing of the thermographic assessment of burns.

The thermographic assessment of burns using infrared imaging has previously been shown to be a useful aid in the estimation of burn depth. In this study, thermographic images of burns, obtained from 65 patients over a 4-year period, were reviewed. An infrared transparent, water-impermeable membrane was used as a wound cover to abolish evaporative cooling artefacts. Single images were obtained from patients with burns to various parts of the body, excluding the hands. A significant change in the temperature of deep burns was observed between days 2 and 3 after injury (chi-square, P < 0.01; Fisher exact probability test between days 2 and 3, P < 0.01). The results of this study suggest that thermography of burns, to assess depth, should be performed within 3 days following the injury.

Adolescent↗

The relationship between aortic diameter and body habitus.

Nine hundred and six men between the ages of 65 and 74 years were screened to determine whether there was a correlation between abdominal aortic diameter and body size. There was no correlation between aortic diameter and weight or obesity but there was a significant correlation with height and age. Sequential enlargement of the aorta was observed in 57 men with aortic diameters above the normal range, none of these were characterised by one particular body habitus: it is suggested that patients in this group should be rescanned regularly.

Aged↗

Radiation-induced antrochoanal fibrosarcoma.

Therapeutic radiation for malignant conditions is known to cause sarcomatous change in an irradiated field after a latent period; equally this change may occur following radiotherapy to benign conditions which may result in a more difficult management problem later. Radiotherapy to benign conditions should be reserved for use after failure of conventional surgery or other interventional techniques.

Aged↗

Rebound tenderness test.

The usefulness of the rebound tenderness test in indicating peritonitis was prospectively assessed in 142 unselected patients admitted as emergencies with abdominal pain and tenderness. It was found to be of no predictive value.

Abdomen, Acute↗