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Biomedical subjects

M I Lytkin

Publications and source records attributed to M I Lytkin.

At least 19 recordsLinked to original sources
PubMed1991

[Autologous bone marrow transfusion in the combined treatment of cancer of the thoracic segment of the esophagus].

Transplantation of autologous bone marrow was performed in 62 patients with carcinoma of the thoracic portion of the esophagus for prophylactics of disturbance of hemopoiesis and severe infectious complications in the postoperative period. With the help of myelokariocytopheresis procurement of the bone marrow was made 2-3 days before starting preoperative radiotherapy. After exfusion of the bone marrow mixture erythrocytes were separated and returned completely and immediately to the patient, myelokaryocytes being frozen. The volume of the bone marrow suspension from 1 patient made up on the average from 300 to 800 ml, the amount of the bone marrow cells in it from 4.5 to 11.2.10(9). Studies of the dynamics of concentrated and volumetric parameters of blood were performed. The functional specific features of the bone marrow erythropoiesis were estimated in the sternal punctate. The use of automyelotransfusion substantially reduced the frequency of infectious complications and, in the author's opinion, it is a fairly effective method of prophylactics and treatment of postoperative anemia.

Anemia↗
PubMed1990

[Use of cryopreserved autologous thrombocytes in cardiac surgery].

Cryopreserved autologous thrombocytes were used for the prevention of thrombohemorrhagic complications after operations with extracorporeal circulation in 17 patients. An obvious hemostatic effect was produced. Studies carried out in cardiosurgical patients showed satisfactory maintenance of the main hemostatic characteristics of the blood platelets during cryopreservation. Plasma thrombocytapheresis in an apparatus allows simultaneous preparation of the autothromboconcentrate and large amounts of autoplasma used for filling the extracorporeal circulation apparatus, and compensation for the blood loss.

Adult↗
PubMed1990

[Esophagogastric bleeding as a complication of isolated thrombosis of the splenic vein].

The literature data and original experience (11 relevant cases) have provided evidence in support of marked diagnostic benefit of ultrasonography and transcutaneous transhepatic portography employed in suspected esophagogastric hemorrhage due to isolated thrombosis. Splenectomy and disconnection of pathological portocaval shunt through short gastric veins present surgery of choice.

Adult↗
PubMed1990

[Late results of ligation of the splenic artery and its embolization in portal hypertension syndrome].

From study of the results of exclusion of the spleen in 87 patients with portal hypertension by ligation of the splenic artery (47) or its truncal embolization (40) with a Gianturko-type spiral, the authors conclude that in some cases these operations reduce portal pressure, manifestations of hypersplenism, and risk of bleeding, but do not guarantee that they will not develop. Ligation of the splenic artery or its truncal embolization is justified as an independent operative intervention when decompression anastomoses cannot be formed or the risk of their performance is extremely high.

Adolescent↗
PubMed1989

[Non-surgical sanitation in patients with obstetrical and gynecological infections].

The intra-aortic++ introduction of a complex of drugs was performed to 34 patients with sepsis of obstetric-gynecological etiology. The disease appeared in 23 patients after extrahospital abortions, in 7 patients after delivery, in 4 patients after operation of cesarean section. Septic pneumonia took place in 23 patients. Antiseptic treatment was also used in all the patients. Recovery was noted in 32 of 34 patients, 23 of them were discharged from the hospital without removal of the uterus. Conclusion may be made that the intra-aortic++ administration of drugs is a highly effective method of treatment of obstetric-gynecological sepsis.

Abortion, Septic↗
PubMed1989

[Comparative evaluation of proximal resections in rectal cancer].

The surgical treatment of rectum cancer in 165 patients with the apparatus AKA-2 for compressive anastomoses was analyzed. The oncological adequacy of proximal resections of the rectum at the distal level of the section not less than 3.5-5 cm from the visually seen margin of the tumor depending on its growth type was shown. Low anterior resection of the rectum in patients with considerable size of the tumors is not oncologically justified.

Adult↗
PubMed1989

[Characteristics of thrombocyte aggregation properties in portal hypertension syndrome complicated by esophagogastric hemorrhage].

An investigation of ADP-induced aggregation of thrombocytes in 62 patients with the portal hypertension syndrome has revealed pronounced functional alterations of blood platelets characterized by a lower aggregation rate, lower rate and degree of thrombocyte deaggregation. More profound alterations were found in patients with cirrhosis of the liver. It was established that the decreased rate and degree of the thrombocyte deaggregation with the growing aggregation rate, change of the aggregation into the irreversible form is a very dangerous portent of gastrointestinal bleeding.

Esophageal Diseases↗
PubMed1989

[Rapid determination of microbial sensitivity to antibiotics by using laser spectroscopy].

A method of express-determination of the susceptibility of microbes to antibiotics is presented based upon the registration by the method of laser spectroscopy of changes of optic properties of cultures at early terms of their incubation in liquid nutrient media with addition of antibiotics. The method was elaborated in 13 standard strains of Staphylococcus aureus and Escherichia coli with antibiotics of different classes, tested on the microflora of pus of patients with sepsis, verified by the method of serial dilutions of the antibiotic. The method makes it possible to obtain the minimum inhibiting concentration of antimicrobial preparations 1 h after the moment of obtaining the native material.

Anti-Bacterial Agents↗
PubMed1989

[Non-operative sanitation of suppurative-septic foci].

The authors made an analysis of their experience with treatment of 63 patients with abscessing pneumonia and gangrene of the lungs, 137 patients with peritonitis, 27 patients with gynecological sepsis, 80 patients with pyo-necrotic foci in lower extremity tissues. They used the method of regional (intraaortal, intraarterial) infusions of drugs which is thought to open new possible ways of nonoperative treatment of pyoseptic foci of various localizations.

Anti-Infective Agents↗
PubMed1989

[Infectious complications after splenectomy in patients with cirrhosis of the liver].

Based on an examination of 105 patients with cirrhosis of the liver with the syndrome of portal hypertension complicated by gastroduodenal bleedings who were subjected to splenectomy (in 86 patients there were proximal splenorenal anastomoses) the authors make a conclusion that infectious complications in the postoperative period in the group under analysis were developing against the background of the concomitant and predisposing conditions and can be compared in their incidence with infectious complications after other similar in severity operative interventions on organs of the abdominal cavity. In remote terms after operation the normalization of the indices of both cellular and humoral immunity was noted.

Adult↗
PubMed1988

[Unsolved problems in the surgical treatment of complicated ulcers of the stomach and duodenum].

The article generalizes an experience of a number of surgical collectives of the Military Medical Academy with the surgical treatment of complicated gastroduodenal ulcers by organ-preserving operations. The authors recommend wider use of such interventions in acute complications of ulcer disease (perforation and bleedings). It is important to abstain from performing such operations on planned patients with very high gastric secretion in order to decrease the amount of recurrences after vagotomy, to choose an adequate draining operation in stenosis. In young patients vagotomy should be combined with antrumresection.

Adult↗