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Biomedical subjects

M I Moreno

Publications and source records attributed to M I Moreno.

13 recordsLinked to original sources

Perineal transsphincteric derivation of urine. Experimental study in rabbits.

AIM OF THE STUDY: We present the experimental results of a new technique that makes use of the anal sphincter to achieve urinary continence in individuals with major congenital defects of the urinary sphincter. METHODS: 50 New Zealand White rabbits were assigned to one of 6 groups and a different surgical procedure was carried out for each group under general anaesthesia with isoflurane alone or isoflurane and local anaesthesia. Variables of interest were: number, consistency and morphology of the faeces, number, shape and location of the stains of urine, histological changes and biochemical parameters in blood. RESULTS AND CONCLUSIONS: The best anaesthetic levels were obtained with 2 % isoflurane and local anaesthesia. The surgical procedure demonstrated its usefulness in achieving urinary continence in all rabbits, although an initial self-limited period of incontinence was common. No histologic alterations were detected, but a significant increase in the levels of urea and creatinine in blood was identified, most likely reflecting an obstructive uropathy.

Anal Canal↗

Comparison of the free radical-scavenging activity of propolis from several regions of Argentina.

Propolis is extensively used in Argentine folk medicine. Alcoholic extracts of propolis from different regions of Argentina were prepared. The extracts were analysed for the determination of total flavonoid content (from 13.3 to 42.6 mg/g of propolis) by using the aluminum nitrate method, UV spectrophotometry and thin layer chromatography. All of them contained high total flavonoid content. It was also observed that all samples of ethanolic extracts of propolis showed free radical-scavenging activity in terms of scavenging of the radical DPPH but the highest activities were found for samples from Tucumán and Santiago del Estero. In all cases with 20 microg/ml of soluble principles, the percentage of DPPH degradation was different (Banda Oeste: 67.5%; Verónica: 45%; Forres: 35%; Saenz Peña: 20% and Juan José Castelli: 55%). These results may justify their use as a source of natural antioxidants.

Argentina↗

[Mycetomas caused by Microsporum canis. Report of one case].

We report an eight years old boy presenting with a pyogenic granuloma of the scalp, generalized alopecia, descamative plates in the neck, trunk and limbs and nail involvement. Cultures for fungus of all these lesions disclosed Microspore canis. The patient was treated with oral griseofulvin, miconazole and topical tolnaftate. Five years later and after several incomplete treatments, the patient returns with a fistulous mass of 15 x 8 cm in the dorsal area whose culture revealed Microspore canis. The mass was excised and oral ketoconazole was indicated. After three months of follow up, the patient was lost from control.

Antifungal Agents↗

[White piedra. Report of a case].

The most common superficial mycosis caused by Trichosporon beigelii is white piedra. We report a 18 years old male that had in several hairs of the scalp, white-yellowish nodules of 1 mm diameter, agglutinated or forming chains, even forming threads, with a greasy aspect. Trichosporon beigelii was identified in cultures. Oral and topical antimycotics were prescribed and the patient was lost from follow up.

Adolescent↗

[Kerion Celsi. A diagnostic problem? Experience with 6 cases].

We report six patients with Kerion Celsi due to Trichophyton verrucosum. Five of the patients were hospitalized with the diagnosis of Staphylococcal abscess. This confusion is due to that highly suppurative and inflammatory nature of the infection. Griseofulvin is the antimicrobial of choice for treatment, associated with imidazolics and corticosteroids to prevent alopecia. The authors suggest that an adequate use of simple microbiological diagnostic tests in the diagnosis of pyodermitis in rural children, may prevent unnecessary hospitalizations and permanent hair loss.

Child↗

[Microbiological study of urethritis in men].

From 1985 to 1987 we obtained urethral samples from 453 patients with a clinical diagnosis of urethritis. N gonorrhoeae was isolated in 55%, a rate that increased along the study period. The most common other agent was U urealyticum alone or in combination with other organisms. Among 82 patients, the incidence of chlamydia trachomatis was 19%. The proportion of Beta-lactamase producing strains among N gonorrhoeae varied form 7% in 1985 to 13% in 87 and 3% in 1988.

Adolescent↗

Bicycle pedalling forces as a function of pedalling rate and power output.

Eleven men with recreational bicycling experience rode a bicycle ergometer with instrumented force pedals to determine the effects of pedalling rate and power output on the total resultant pedal force, Fr, and the component of the force perpendicular to the crank arm. The force patterns were obtained at power outputs of 100 W and 200 W for pedalling rates of 40-120 rpm in intervals of 10 rpm. Data were not obtained at 40 rpm at the 200 W power output. The Fr averaged over a crank cycle (Far) was lowest at 90 rpm and 100 W, a value statically different (P less than 0.05) from those at 40, 50, and 120 rpm. At 200 W, the Fr was lowest at 100 rpm, a value statistically different (P less than 0.05) from those at 50, 60, and 70 rpm. The Far varied widely (range of 30% of mean for all subjects) for individuals at a given power output. The results suggest that pedalling at 90-100 rpm may minimize peripheral forces and therefore peripheral muscle fatigue even though this rate may result in higher oxygen uptake.

Adult↗

[Detection of Chlamydia trachomatis in urethral samples by direct immunofluorescence].

The presence of Chlamydia trachomatis was studied by the direct immunofluorescence test, as also was that of Neisseria gonorrhoeae, Mycoplasma and Ureaplasma by the standard methods, in 82 patients with urethral discharge. Ch. trachomatis was found in 19.5% (16) of the cases and in 11 of them (68.8%) there was association with the other bacteria investigated. This eleven patients presented a scanty gelatinous discharge.

Antibodies, Monoclonal↗

Parenteral nutrition in hyperemesis gravidarum.

Hyperemesis gravidarum (HG) is a clinical condition that threatens fetal viability and even the mother's life when the severity of symptoms almost completely prevents the intake of food. Parenteral nutrition (PN) is a possible alternative. We present eight patients with HG. There were 10 PN treatments because two of the patients required the treatment twice. There were 9 central venous and 1 peripheral treatment delivery. The average age of the patients was 27.5 yr. Gestational ages varied from 8 to 19 wk. PN treatments were formulated as amino acid and glucose solutions (fat emulsions in 2 of the 8 cases) blended with vitamins and electrolytes. These treatments lasted 5-16 days. Before PN deliveries were initiated, five of the patients presented some degree of protein-calorie and/or visceral protein malnutrition. All of them showed minor liver dysfunction, which did not change during PN. Newborns were term deliveries, except for one case of missed abortion. Results show that PN constitutes a therapeutic alternative in cases of HG that do not respond to the standard treatment of parenteral hydration and antiemetics. In fact, symptoms disappear promptly, and no significant complications arise.

Adult↗