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Biomedical subjects

M I Popov

Publications and source records attributed to M I Popov.

13 recordsLinked to original sources
PubMed1990

[A method of managing the bronchial stump after surgical and combined treatment of patients with cancer of the lung].

The authors developed a complex of measures for the prevention of purulent bronchopleural complications, among which the "stumpless" method of manual treatment of the bronchus is the principal measure. With this method, the incidence of a bronchial fistula reduced to 0.5% in lobe-bilobectomy and to 1.4% in pulmonectomy. Due to the sharp drop in the incidence of this complication, the total postoperative mortality reduced to 3.3%. The developed methods of manual treatment of the bronchus made it possible to level out the difference in the incidence of a bronchial fistula in surgical and combined treatment (preoperative radiotherapy), 2.1% and 3.9%, respectively. The "stumpless" methods of manual treatment of the bronchus in lung carcinoma improve the conditions for oncological radicalism of the operation and prevent economical losses by reducing the hospital stay of patients.

Bronchi↗
PubMed1989

[Phagotherapy of postoperative suppurative-inflammatory complications in patients with neoplasms].

The authors assess the efficacy of phage therapy ofsuppurative and inflammatory complications in oncological patients. A clinical and laboratory analysis has involved 131 patients whose etiotropic therapy consisted of bacteriophages (65 patients) and antibiotics (66). Medicinal phages, manufactured by the Tbilisi Research Institute for Vaccines and Sera, have been administered according to 3 schemes: (1) parallel with antibiotics, (2) after long ineffective antibiotic therapy, (3) phages alone starting from the onset of the purulent complication. The preparations have been prescribed with due consideration for the isolated microflora sensitivity. Incorporation of phages in combined therapy of infectious complications has yielded positive results in 81.5% of cases, whereas antibiotics have proved effective in but 60.6%. The efficacy of phage therapy depends on the type of pyoinflammatory complications (the results are the best in the management of wound infections), the microflora pattern of the purulent foci (phages are the most effective with a corresponding monoinfection), characteristics of the therapeutic phages proper (Pseudomonas aeruginosa phage is characterized by the highest therapeutic activity, as compared to staphylococcal and other phages).

Anti-Bacterial Agents↗
PubMed1975

[Surgical fixation of the spine in fractures in the thoracic and lumbar segments].

Posterior alloplastic fixation of a damaged spinal portion was accomplished in 68 patients. In 20 cases fracture was associated with spinal dislocation. In such cases when a compressive spinal fracture is accompanied with insignificant signs of spinal concussion one should follow an expectation policy, since an early operation may be inherent in some additional trauma and result in inhibition of regenerative processes. For spinal fixation Lavsan was employed in 23 patients, a tightening device-in 28, metallic CITO plates-in 17. In 6 objects fixation with the plates was associated with arthrodesis of intervertebral junctures. Late results were studied in 49 patients. In 40 cases the results were good, in 4-satisfactory, in 5-poor. The best results were noted in fixation of the damaged portion with the plates, these should be preferred to other fixators in fracture-dislocation of the spine.

Adolescent↗
PubMedDate not supplied

[The functional status of the peripheral blood neutrophilic granulocytes determined by the corona-forming index during tumor growth].

It was established that the formation of a primary neoplastic focus, a recurrence of the disease, and the development of a second focus in a previously treated oncological patient occur mainly in reduced indices of corona formation; in extension of a malignant process (carcinoma of the stomach and lungs), in contrast, the corona-forming activity of the segmented neutrophils is characteristically increased. The studied test may be of prognostic importance in appraising the efficacy of the treatment of patients with carcinoma of this localization. The mechanisms determining the trend of changes in the corona formation in a neoplastic process require further study.

Citrates↗
PubMedDate not supplied

[Catecholamines in the erythrocytes of cancer patients].

Cytochemical study of catecholamines in red blood cells of lung cancer patients disclosed the specific features of their content depending on the histological structure of the tumor and the advancement of the tumor process. The catecholamine content was lowest in patients with III-IV stage non-oat cell lung carcinoma and highest in patients with apudomas. The indices studied in groups of patients with benign processes in the lungs and with stage I-II non-oat cell carcinoma did not differ essentially from those in the controls.

Adolescent↗