Biomedical subjects

M I Rose

Publications and source records attributed to M I Rose.

3 recordsLinked to original sources

PubMed1987

Type A behaviour pattern: a concept revisited.

It is generally accepted that the type A behaviour pattern is a risk factor in the development of coronary artery disease (CAD). Type A people have been characterized as hard-driving, competitive, aggressive and hurried. A number of investigators have attempted to correlate these facets of type A behaviour with increased risks of CAD. However, there have been conflicting results, primarily owing to differences in methods and CAD outcomes and inconsistencies associated with measuring the type A behaviour pattern. As a result, researchers have begun to focus on subcomponents of the type A behaviour pattern, particularly hostility and anger, that appear to be more reliable predictors of CAD outcome. A reconceptualization of the type A behaviour pattern is required.

Adult↗

PubMed1983

The effects of anxiety management training on the control of juvenile diabetes mellitus.

The present study was designed to determine whether diabetic control could be improved through the direct psychological management of stress and anxiety. Five poorly controlled female adolescent diabetics ranging in age from 15 to 18 years were used as subjects. All were seen on an outpatient basis over a 6-month period. A single-subject format employing a multiple-baseline design across subjects was used. The independent variable used was a technique known as anxiety management training. Baseline, attention-control, and treatment data were collected on a number of dependent measures. Subjective estimates of anxiety and tension by each subject were gathered on a biweekly basis using the Multifactorial Scale of Anxiety. Diabetic control was assessed daily using the Diastix method and weekly using the 24-hr quantitative glucose method. Data on the five subjects suggested that improved control of stress and anxiety had a positive effect on diabetic regulation. Lower and more stable urine glucose levels using both urine testing methods were found. However, no decreases in the subjects' personal assessment of tension and anxiety were evident.

Adolescent↗

PubMed1979

Migration of lymphoblasts to the small intestine. III. Strain differences and relationship to distribution and duration of Trichinella spiralis infection.

In NIH strain mice, in which the majority of Trichinella spiralis are located in the anterior half of the small intestine early in the enteral phase of infection, enhanced localization of mesenteric lymphoblasts, nylon wool separated mesenteric T-lymphoblasts and even oxazolone sensitized peripheral lymphoblasts is most prominent in the anterior region of the small intestine. As the worms move to the posterior half of the small intestine, enahnced localization of lymphoblasts is observed in that region only. In BALB/c mice, in which most of the worms are located in the posterior half of the small intestine, enhanced localization of lymphoblasts is primarily in that region. Expulsion of the worms commences within 2--3 days of a large increase in the number of lymphoblasts localizing in the anterior region of the small intestine in NIH strain mice and likewise follows a second and larger increase in the number of lymphoblasts localizing in the posterior region of the small intestine of BALB/c mice.

Animals↗