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Biomedical subjects

M Ia Bogomazov

Publications and source records attributed to M Ia Bogomazov.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[The effect of the zinc content in the rations of experimental animals on the absorption, distribution and accumulation of cadmium chloride in the body with different methods of administration].

Intravenous (20 kBk) and intragastric (400 kBk) cadmium chloride administration to 45 white noninbred rat males kept for a month on a semisynthetic isocaloric diet including 0.0005 and 0.001% zinc were evaluated for absorption and distribution. Radionuclide findings provided the conclusions that: the absence or excess of zinc in the diet stimulates cadmium absorption from gastrointestinal tract; cadmium distribution in the viscera (the liver, kidneys, pancreas) varies with route of entry, the least accumulation of oral cadmium in the above viscera is observed in animals receiving optimal zinc quantities.

Administration, Oral↗
PubMedDate not supplied

[The characteristics of the development of experimental apical periodontitis in irradiation-induced immunodeficiency].

Apical periodontitis was induced in 24 mongrel dogs (16 experimental and 8 reference ones) over the course of total x-ray exposure. Analysis of clinical and physiologic data, hematologic parameters, and roentgenograms of the jaws of the two animal groups has shown the development of immunodeficiency state in the experimental animals due to exposure to ionizing irradiation in a dose of 1.5 Gy and an earlier development of destruction foci in bone tissue with diffuse involvement of the dental apexes.

Animals↗
PubMedDate not supplied

[Effect of the amount of protein and calcium in the diet on cadmium chloride distribution and accumulation in the body when administered by different routes].

The authors studied distribution and accumulation of cadmium chloride after its intravenous (i. v.) or intragastric (i. g.) administration to experimental rats, which received diets with varying content of protein (18, 30 and 5%) and calcium (0.6, 2.4, 0.1%), during one month. A high level of cadmium chloride was recorded in the liver after i. v., and in the kidneys after i. g. administration. The highest level of cadmium chloride was observed in the kidneys after i. g. administration to rats which were given diets with high protein content. A balanced content of protein and calcium in the diet promoted diminution of cadmium chloride accumulation in the body.

Administration, Oral↗