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M Ia Ratner

Publications and source records attributed to M Ia Ratner.

93 records · Page 6Linked to original sources

[The tubulointerstitial changes in different clinical and morphological types of chronic glomerulonephritis].

As shown by the data available on 228 patients with chronic glomerulonephritis, tubulointerstitial alterations (TIA) occur primarily in mesangiocapillary glomerulonephritis, focal-segmental glomerular hyalinosis/sclerosis, diffuse fibroplastic glomerulonephritis as well as in active nephritic and nephrotic-hypertensive types. In 186 patients with chronic glomerulonephritis chronic renal insufficiency evidencing enhanced progression (EP) if arose within 7 years since the disease onset in the presence of TIA was registered significantly more frequently. TIA patients demonstrated EP as a rule in prognostically unfavorable active nephritic and nephrotic-hypertensive types. The relationship between TIA and EP may be explained by their association with unfavourable clinical types suggesting poor prognosis.

Adolescent↗

[The dependence of the progression of chronic glomerulonephritis on the clinical and morphological types of glomerulonephritis and on the tubulointerstitial changes].

Progression of chronic glomerulonephritis (CGN) is strongly associated with morphologic type of the disease, tubulointerstitial changes, some clinical syndromes. The aim of the study was to trace relations between the onset of chronic renal failure within 7 years since the diagnosis (fast progression of CGN--FP CGN), CGN clinical variant according to M. Ia. Ratner et al. classification (1987) and histomorphological changes in the renal biopsy. Unfavorable clinical types (active nephritic types and nephrotic-hypertensive type) proved dominating predictor of FP CGN not only because of close relationship between these type and FP CGN but also due to FP CGN occurrence in morphologically unfavorable morphological types and tubulointerstitial changes in line with concomitant unfavorable clinical types.

Adolescent↗