[A clinical study of auditory hallucination by single photon emission computed tomography (SPECT) using N-isopropyl-p-[123I] iodoamphetamine (IMP)].
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Biomedical subjects
Publications and source records attributed to M Ii.
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The case of an alcoholic patient with auditory hallucination is reported in which [123I] iodoamphetamine (IMP) brain imaging demonstrated increased accumulation in the left superior temporal lobe which corresponded to the left primary and secondary auditory areas. Thus, IMP brain scans seem to have the potential to objectively localize the brain abnormalities in auditory hallucination.
Rat-peritoneal macrophages are shown to be able to take up glycoproteins terminated by galactose as well as those by mannose and/or N-acetylglucosamine. A lectin responsible for the uptake of galactose-terminated glycoproteins was isolated by affinity chromatography on a column of Sepharose 4B-asialoorosomucoid. The macrophage lectin isolated shared many properties in common with the well-established hepatic lectin specific for galactose/N-acetylgalactosamine. Thus, the lectin bound to asialoglycoproteins specifically, and the binding was inhibited by galactose and N-acetylgalactosamine. The lectin had a single major component of mol. wt. 42,000 as well as two minor components of 60,000 and 65,000, and required calcium for binding. In addition, the macrophage lectin was immunologically crossreactive with the hepatic lectin. Despite these similarities, however, the macrophage lectin was differentiated from the hepatic lectin in molecular size, relative preponderance of minor components, and titration profile with the antibodies raised against the hepatic galactose/N-acetylgalactosamine-specific lectin.
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Explore the source record for details and available documents.
Explore the source record for details and available documents.