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Biomedical subjects

M Imanaka

Publications and source records attributed to M Imanaka.

At least 37 records · Page 2Linked to original sources
PubMed1997

Uterine blood flow velocity waveforms during early postpartum course following caesarean section.

OBJECTIVE: To assess the change of uterine blood flow after Caesarean section. STUDY DESIGN: Doppler flow velocity waveforms were acquired from the uterine arteries and small arteries near the myometrial wound detected by transvaginal power Doppler ultrasonography in 23 patients on the 3rd, 6th and 9th postoperative days. RESULTS: The resistance index for the uterine artery did not show any change during the study period, while that for the small arteries slightly decreased. CONCLUSION: Uterine blood flow resistance after Caesarean section did not show any change during the early postpartum period.

Blood Flow Velocity↗
PubMed1997

Umbilical venous pulsation and regional circulatory disturbance.

The umbilical cord conditions at the point where regional umbilical venous pulsation occurred were examined in 15 patients between the 28th and 40th gestational week. The patients delivered appropriate-for-date infants without anomalies. Regional venous pulsation was observed in cases of large-angle cord winding (especially more than 60 degrees). It was also observed where the umbilical cord was compressed by the fetus, uterine wall or placenta, even if the umbilical cord was straight. From these findings, we concluded that regional umbilical venous pulsation is the result of regional circulatory disturbance of the umbilical cord.

Female↗
PubMed1997

Umbilical venous pulsation associated with hypercoiled cord in growth-retarded fetuses.

Venous pulsatile flows were detected by pulsed Doppler flow velocimetry throughout the entire umbilical cord in 2 cases of intrauterine growth retardation. Although the hearts of these fetuses had no anomalies and their inferior vena cava flows had normal flow velocity patterns, their cords were severely coiled. In these cases, the pulsatile flow in the umbilical cord vein was caused not by an increase in the preload of the fetal heart, but only by hypercoiling of the umbilical cord. This phenomenon also suggests that the coiled umbilical cord exerts a pump-like effect known as a 'pulsometer'.

Adult↗
PubMed1997

Favorable response to heparin in a pregnant woman with possible glomerular thrombosis as a complication of systemic lupus erythematosus and anti-phospholipid antibody syndrome.

A rare case of possible glomerular thrombosis during pregnancy is reported in a patient with active systemic lupus erythematosus and the presence of anti-phospholipid antibodies. Acute renal impairment was restored by administering infusions of heparin. Cesarean section was performed due to fetal distress, and resulted the live birth of a healthy infant.

Adult↗
PubMed1996

Prenatal diagnosis of succinyl-coenzyme A:3-ketoacid coenzyme A transferase deficiency.

Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency is a rare disorder of ketone body catabolism. In the present study, we prenatally diagnosed SCOT deficiency in a fetus in a family of which the proband was the first patient with SCOT deficiency identified in Japan, by analysis of enzyme activity levels in samples of chorionic villi and cultured amniocytes. In the fetus of the family, SCOT activity was not detected in either chorionic villi or cultured amniocytes. Since the levels of SCOT activity in control chorionic villi were close to our minimal detectable level and were much lower than those in control cultured amniocytes, enzyme assay in cultured amniocytes was more feasible than that in chorionic villi for prenatal diagnosis of SCOT deficiency. No elevated accumulation of 3-hydroxybutyrate or acetoacetate was detected in the amniotic fluid of the fetus. To our knowledge, this report is the first of prenatal diagnosis of SCOT deficiency.

3-Hydroxybutyric Acid↗
PubMed1996

Intake ratio of water-insoluble dietary fiber to the water-soluble one in Japanese: an estimation on dietary records and the secular consideration on the national nutrition survey.

Thirty-four foods were analyzed in order to determine the content of water-soluble dietary fiber (SDF) and insoluble dietary fiber (IDF). Using the results with the standard table for 227 foods, the intake ratio of IDF/SDF of an average Japanese was calculated for the period 1946-1990. The ratio was 3.22 in 1990 as calculated on the food intakes shown in the national nutrition survey, and the secular change was not detected since 1946 when the ratio was 3.30. The ratio was also shown to be well preserved between types of households including the age of the head. Using dietary records of 60 healthy city workers (average 42.8 years) for 4 weeks, however, the weekly average ratio for an individual was found to vary in the range of 2.25-5.13 although the total average for 60 individuals was 3.33. Thus, the well preserved IDF/SDF intake ratio for an average Japanese showed, on the contrary, a wide variation of food selection between each person.

Adult↗
PubMed1995

Massive fetomaternal hemorrhage.

We evaluated the potential prognostic factors for fetomaternal hemorrhage (FMH). Sinusoidal heart rate pattern and decrease in fetal movement are considered important signs of FMH. However these findings were detected in only two of six cases of FMH and were thought to be late signs of FMH. Fetal hemoglobin levels in the maternal circulation for infants born alive following FMH were less than 5%. Our findings suggest that this amount of blood loss could cause fetal death.

Adult↗
PubMed1995

Umbilical cord venous pulsation in normal fetuses and its incidence after 13 weeks of gestation.

A total of 1175 umbilical venous Doppler flow velocity waveforms were acquired from 449 normal pregnant women whose fetuses were delivered at term without neonatal asphyxia or anomalies. Arterial and venous flow velocity waveforms were acquired from a free loop of the umbilical cord. The incidence of umbilical venous pulsation decreased from 30.4% at 13-14 weeks of gestation to 14.8% at 21-22 weeks of gestation. After 23 weeks, this incidence was settled within 5.0-7.8%. There was no difference between the umbilical arterial resistance index of the fetuses with venous pulsation and without pulsation before 22 weeks. But the resistance index was lower in the pulsatile fetuses than in the nonpulsatile fetuses after 23 weeks of gestation. The origin of venous pulsations before early second trimester was suspected to be different from that after late second trimester.

Blood Flow Velocity↗
PubMed1995

Tracheo-esophageal shunt speech: report of an unusual case.

A rare case of laryngectomee who acquired TE shunt speech is reported. Our patient was a 64-year-old woman with laryngeal cancer (glottic type T3N0M0). She underwent laryngectomy in 1990, and a Komorn tracheo-esophageal shunt operation was performed simultaneously. A voice prosthesis (BIVONA) was inserted into the shunt, but the voice valve was not used. She acquired shunt speech soon after the operation, and there was no need to close the tracheostoma during phonation. Fiberoptic, X-ray and aerodynamic findings of the shunt and esophagus were as follows: (i) The one-way valve of the voice prosthesis was open during inspiration and closed during phonation. (ii) Swallowing of air, as seen in esophageal speech, was not observed. (iii) The neoglottis was in the upper part of the esophagus. It was concluded that the air for the vibration of the neoglottis entered the esophagus through the T-E shunt during inspiration.

Female↗
PubMed1994

Measurement of fetal urine production in mild infantile polycystic kidney disease--a case report.

It is generally recognized that the sonographic findings of infantile polycystic kidney disease (IPKD) are bilaterally enlarged kidneys, oligohydramnios, an absent fetal bladder, and the typical kidney texture. Since there is a broad spectrum of renal compromise with IPKD, in utero diagnosis is thought to be limited to the severe forms. This paper reports a mild case of IPKD, where the in utero diagnosis was established by measuring fetal urine production and amniotic fluid volume serially during pregnancy, and by ultrasonographic examination of fetal kidneys.

Adult↗
PubMed1994

[Cytofluorometric DNA analysis in different histological patterns of thyroid papillary carcinoma].

Some papillary carcinomas of thyroid glands contain not only typical papillary structures but also various histological features in the same tumor. To investigate how areas with variable histological features differ in proliferative activity and how these differences influence the biological behavior of the whole tumor, we measured DNA contents by cytofluorometry in six papillary carcinomas with different histological features in the same tumor. DNA ploidy patterns were determined and the percentage of S plus G2M phase cells (S + G2M fraction) was calculated only in diploid tumors to assess the proliferative activity. The following conclusions were drawn. 1) It was demonstrated that there were differences in proliferative activity among areas with variable histological features in 4 of six tumors. 2) In the tumors which invaded adjacent tissues, the proliferative activity of the invasive area tended to be higher than that of the original area of the tumor. Therefore, the possibility exists that more precise evaluation of the biological behavior of the tumor can be obtained by measuring DNA contents of the tumor cells in invasive areas. 3) There was the gap in S + G2M fractions among some tumors with the same histological differentiation. Accordingly, DNA analysis of tumors would be of value in estimating proliferative activity.

Aged↗
PubMed1993

Significance of fetography in prenatal diagnosis of limb-body wall complex (LBWC).

The diagnosis of limb body wall complex (LBWC) by ultrasonography does not usually present a problem. The major difficulty we found was severe oligohydramnios or a very complex relationship between the herniated viscera and the deformities. We performed fetography in a pregnant woman with fetal anterior abdominal wall defect at the 28th gestational week to show a peculiar structure of intrauterine membranes of LBWC, and we could obtain a successful prenatal diagnosis of LBWC.

Abdominal Muscles↗
PubMed1993

[Combined treatment of head and neck cancers by radiation therapy and chemotherapy with a small dose of CDDP].

Two-route infusion chemotherapy with a smaller dose of CDDP was applied for combined modality treatment with radiation therapy for head and neck cancer from 1985 to 1992. To determine the appropriate dose of CDDP in this treatment, we investigated parameters concerned with its toxicity by comparing two groups given 5 and 10 mg of CDDP as a daily dose. Complete response was attained in 18 of 24 cases in the 5 mg group and 8 of 11 cases in the 10 mg group. The toxicity due to CDDP in this protocol was found generally to be slight in both groups. Among the parameters of toxicity, creatinine clearance was most affected. A decrease in 24 hr. creatinine clearance was noted in 15 of 29 cases in the 5 mg group and 10 of 12 cases in the 10 mg group. We had to discontinue this treatment after the first course because of lowered creatinine clearance in a patient in the 5 mg group. Stomatitis due to radiation therapy appeared to become worse in combination with this chemotherapy. The 10 mg dose of CDDP can be applied as a safe combination treatment with radiation therapy for head and neck cancer. To improve the outcome of this treatment modality for carcinomas of the tongue and oral floor, the 10 mg dose of CDDP was thought to be more beneficial. However, in the case of cumulative doses of CDDP over 100 mg, precaution should be taken to avoid the risk from the toxicity of more CDDP administration.

Adult↗
PubMed1992

Pulsatile umbilical venous flow and its clinical significance.

OBJECTIVE: To determine the prevalence and significance of pulsatile waveforms from the umbilical vein. SETTING: A tertiary referral clinic for high risk pregnancies. SUBJECTS: 209 fetuses from 24-41 weeks gestation. MAIN OUTCOME MEASURES: The presence of pulsatile waveforms in the umbilical vein and the pregnancy outcome. RESULTS: 9/209 fetuses demonstrated pulsatile waveforms and seven had severe growth retardation or congenital anomalies of the heart. Pulsatile flow and abnormalities of the inferior vena cava waveforms were observed in these seven but not in the two infants who were born at term. Double pulsations are described for the first time. CONCLUSION: Examination of the umbilical venous waveform for pulsatile flow is a useful test as it indicates the presence of asphyxial cardiomyopathy or congenital heart lesions.

Blood Flow Velocity↗
PubMed1992

New technologies for the management of preterm premature rupture of membranes.

The catheterization described is still incomplete, posing many problems yet to be solved. However, this method has shed light on new issues, including the intraamniotic administration of antibiotics against amniotic fluid infection and fetal infection, amnioinfusion of saline for oligohydramnios, and development of artificial amniotic fluid. These issues are much easier than the nursing of extremely small premature babies and should be solved by the collective wisdom of obstetricians.

Amniotic Fluid↗
PubMed1990

Effects of far-infrared radiation on lactation.

Massage and warm compresses to the breast have been commonly used for stimulating and/or increasing blood flow to the breasts, and for enhancing lactation consequently. However, more effective and easier remedies seem to be necessary. The vasodilating and warming effects of ceramics far-infrared radiation were studied. Based on the results obtained, the effect of a ceramic disc on lactation, attached to the breast skin, was evaluated in 27 puerperal women who had had poor lactation previously and in 36 with currently poor lactation monthly until weaning. Approximately 3/4 of these puerperal women enhanced lactation significantly one month after attachment and 1/2 of the women were able to breast-feed until weaning. Thus, we found that ceramics far-infrared radiation may be an effective remedy for enhancing lactation.

Ceramics↗