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Biomedical subjects

M Imaz

Publications and source records attributed to M Imaz.

17 recordsLinked to original sources
PubMed2001

[Detection of syncytial respiratory virus in clinical samples using a RT-PCR technique].

From November 2000 to May 2001, 208 clinical samples were analyzed for respiratory infection. Parallel to the detection of the syncytial respiratory virus (SRV) by solid phase immunoassay (EIA) and rapid culture in shell-vial or conventional tube, a reverse transcription polymerase chain reaction (RT-PCR) technique was developed. The procedures were complimentary and useful in the diagnosis of respiratory infections due to SRV, both in children and adults.

Humans↗
PubMed1995

Newborn universal immunisation against hepatitis B: immunogenicity and reactogenicity of simultaneous administration of diphtheria/tetanus/pertussis (DTP) and oral polio vaccines with hepatitis B vaccine at 0, 2 and 6 months of age.

The reactogenicity and immunogenicity of the administration of recombinant vaccine against hepatitis B simultaneously (but at separate sites) with diphtheria/tetanus/pertussis (DTP) and oral polio vaccines were examined. Six hundred and twenty-six children (group I) were given hepatitis B vaccine at 0, 2 and 6 months of age; the other vaccines were administered at 2, 4 and 6 months of age. A control group of 731 children (group II) received only DTP and oral polio vaccines. The results showed that 93% of the infants in group I had anti-HBs titres above the protective level ( > or = 10 mIU ml-1) after vaccination. There were no differences in the immune responses for DTP and polio between the two study groups. The vaccine efficacy against poliomyelitis was 96% for serotype I, 100% for serotype II and 97-98% for serotype III. Of the infants in both groups, 97% had antibodies against B. pertussis; all children were positive for tetanus and diphtheria. There were no differences in the incidences of general reactions between groups. Local swelling and redness were reported following 4.2 and 4.4%, respectively, of all injections of hepatitis B vaccine. These reactions were reported following 31 and 33%, respectively, of all doses of DTP vaccine. It can be concluded that the simultaneous administration of hepatitis B vaccine with the DTP and polio vaccines is well-tolerated; hepatitis B vaccine remained highly immunogenic and did not interfere with the immune response to the other antigens.

Diphtheria-Tetanus-Pertussis Vaccine↗
PubMed1994

[Varicella pneumonia in the adult].

In the adult, the primary infection by the varicella-zoster virus acquires an unusual severity due to several complications, the most frequent of them being pneumonia. The authors analyze the clinical, epidemiological, serological and radiological data of the only two cases of varicellous pneumonia in the adult at a general hospital during the past 5 years. They highlight as the main characteristics: easiness of diagnosis, dissociation between clinical and radiological signs and the excellent therapeutical response to the early administration of intravenous Aciclovir. They comment as well the risk factors of this complication and the criteria for hospitalization.

Acyclovir↗
PubMed1993

Isolation and distribution of Streptococcus suis capsular types from diseased pigs in Spain.

A total of 65 isolates of Streptococcus suis was recovered from various tissues of diseased pigs. Almost 96% of all these isolates could be categorized as one of capsular types 1 to 22 and 1/2. Capsular type 2 was the most prevalent and represented 53.8% of all isolates, followed by capsular types 1 (9.2%), 1/2 (7.7%) and 8 (4.6%). Brain-meninges, multiples tissues and lungs were the source of the majority of the isolates. A total of 37% of S. suis isolates, mainly from brain-meninges, were found in pure culture. The antimicrobial susceptibility pattern of S. suis isolates was determined.

Animals↗
PubMed1989

[Intestinal infections caused by Aeromonas].

We have identified 38 instances of intestinal infection by Aeromonas and 4 by Plesiomonas in 16,184 coprocultures carried out during a 4 year period in the HCU of Zaragoza. The low prevalence can be related with the fact that specific media for the recovery of these organisms were not used. The species Aeromonas sobria (47.36%) and A. caviae (39.47%) were more common than A. hydrophila (13.15%). Aeromonas were isolated from patients with and without intestinal disease. The occurrence of gastrointestinal disease was independent from the type of Aeromonas species isolated (p greater than 0.1). We did not find significant differences when we compared patients with and without diarrhea, the rates of the strains that produced gas from glucose, and those of the strains that did not produce arabinose acid. The rates of positivity for lysine decarboxylase and Voges-Poskauer were significantly more common in the strains isolated from symptomatic patients. The sensitivity to cephalothin (MIC less than or equal to 8 micrograms/ml) can be an adequate marker to differentiate A. sobria from the other two species (p less than 0.01).

Aeromonas↗