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Biomedical subjects

M Imhoff

Publications and source records attributed to M Imhoff.

30 records · Page 2Linked to original sources

[Analgesia and sedation of ventilated patients in intensive care medicine].

Any patient admitted to an intensive care unit requires individual analgetic and sedative treatment, depending on type and severity of the disease with its associated physical and psychic problems. There is a wide range of possible medicaments and combinations of these from among which the authors investigated combinations of the short-action opiates fentanyl and alfentanyl and midazolam, a benzodiazepine, short-action as well. These were tested for their effects on several circulatory parameters, intracranial pressure, wake-up behaviour, and selected hormonal parameters of mechanically ventilated patients. Both analgosedation schemes yielded best results, when compared to other combinations also continuously administered through perfusion. Individually adapted synchronisation of the patients to respirator and therapeutic concept proved to be practicable at any time, in spite of that fixed combination of analgetic with sedative.

Alfentanil↗

[Late results of surgical management of medial femoral neck fractures by spongiosa traction screws].

In 36 cases of medial fracture of the femoral neck percutaneous compression osteosynthesis by a specific traction-screw was carried out. During a 3-year follow up five femoral head necroses and three cases of non-union occurred. 28 patients showed good or excellent results. Comparison with results of AO-spongiosa screws and sliding-screw plate reveals no significant differences. Due to small additional operative trauma this percutaneous fixation technique is an appropriate alternative of osteosynthesis of medial fractures of the femoral neck, especially in polytraumatised patients and old patients with high operative risk.

Adolescent↗

Intraoperative autotransfusion with a new disposable system.

In the past 2 years we have used a simple, disposable set for intraoperative autotransfusion. The system consists of a rigid plastic case with a flexible bag inside constituting a 600 ml reservoir which can be connected to any suitable vacuum source. We used it so far in 56 patients undergoing various vascular operations who were autotransfused a total of about 160 units of blood without any complications with regard to blood coagulation or hemolysis.

Blood Transfusion, Autologous↗

[A recent procedure for intraoperative autotransfusion].

At the surgical unit of the University of Cologne a new system for autotransfusion (Solcotrans) was used in 18 patients. This system consists of a plastic case connected with a vacuum pump by an airtube. After filling the plastic case with 50 ml sodium citrate, 450 ml of blood can be aspirated by the surgeon and be reinfused by the anaesthesiologist. The system was used in shunt-surgery at portal hypertension, at venous thrombectomy and at aneurysms of the aorta abdominalis. Through this, stored blood was not necessary in 13 operations.

Aorta, Abdominal↗

[A new method for intraoperative autotransfusion].

In the surgical department of the University of Cologne a new system for autotransfusion (Solcotrans) was used 74 times in 18 patients. This system consists of a plastic case connected with a vacuum pump by an air tube. After filling the plastic case with 50 ml of sodium citrate, 500 ml blood can be aspirated by the surgeon and reinfused by the anaesthetist. The system was used in venous thrombectomy, in aneurysms of the abdominal aorta and in shunt surgery due to portal hypertension. Thus stored blood was not necessary in 13 operations.

Aortic Aneurysm↗

Delayed cutaneous hypersensitivity after multiple injury and severe burn.

LetHality and overall prognosis after multiple injury and severe burn are determined to a major degree by the incidence and severity of infectious complications. Immunological reactions are influenced by the extent of trauma. Multitest Mérieux is an appropriate and an easily applicable means to delayed hypersensitivity testing (DHT). This study investigates to what extent Multitest Mérieux can help to predict the prognosis of multiply injured and severely burnt patients and whether new therapeutic measures can be recommended. This study encloses 52 patients during 1985: 16 severe burns, 20 multiple injuries with craniocerebral trauma and 16 without. Beginning with the day of injury standard laboratory and cardiopulmonary parameters were recorded every 48 hours. Delayed hypersensitivity testing was performed using Multitest Mérieux. The extent of trauma was determined by help of the ISS. All quantitative laboratory and cardiopulmonary parameters showed no significant changes in correlation to the clinical course during the period under investigation. However, a significant correlation between Multitest reaction at days six and eight and its overall results and the rate of infectious complications was found. Moreover, the extent of trauma measured by ISS shows a positive correlation with the rate of anergic reactions in Multitest. Thus Multitest Mérieux is an easily applicable and reliable means to the assessment of the prognosis after multiple injury and severe burn. Therapeutical recommendations beyond today's intensive care concepts cannot be given.

Brain Injuries↗