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Biomedical subjects

M Inatomi

Publications and source records attributed to M Inatomi.

31 records · Page 2Linked to original sources
PubMed1991

Errors in IOL power calculations for axial high myopia.

We studied 115 eyes with axial lengths of 27 mm or more after implantation of a posterior chamber intraocular lens in order to determine discrepancies between the predicted refractions and the actual postoperative refractions. We then reviewed the three major variables used to predict refractions in these eyes--corneal curvature, anterior chamber depth, and axial length measurements--in an attempt to determine whether any of these variables were correlated with the discrepancies. We found that the main reason for postoperative refractive error was inaccurate measurements of preoperative axial length.

Eye↗
PubMed1990

A simple modified SRK formula for severely myopic eyes.

We describe our modification of the most accurate intraocular lens power calculation formula currently used, the SRK formula, to improve the accuracy with which it can be used to calculate the power of IOLs that are implanted in severely myopic eyes, especially in those with exceptional axial length. This modified formula, which we call the L-SRK, is I = A - 2.5 L - 0.9 K - 1.69R - 1.69 (where I = the actual implanted IOL power; A = the A-constant; L = the axial length; K = the average keratometer reading; and R = the predicted postoperative refraction). The results achieved using this modified formula demonstrate its superior accuracy in calculating lens powers for severely myopic eyes.

Humans↗
PubMed1989

A new intraocular lens formula for high myopia.

We developed a formula suitable for calculating intraocular lens power for eyes with axial lengths of 27 mm or greater. We then used this formula in a prospective study to determine its reliability in 32 eyes. In these latter cases the mean error between predictive postoperative refraction and actual postoperative refraction was 0.36 D, with 67% of the cases having less than 1.0 D error; 84% of the cases having less than a 2.0 D error; and no cases having an error greater than 3.0 D. The new formula provided greater accuracy for these highly myopic eyes than the SRK, SRKII, Hollady, and Thompson formulas.

Adolescent↗
PubMed1988

Ocular hypotensive effects of monoamine oxidase-A inhibitors in rabbit.

The effects of monoamine oxidase-A (MAO-A) inhibitors with epinephrine on intraocular pressure in the pigmented rabbit were studied. MAO-A inhibitors were used topically with or without various concentrations of epinephrine. For the measurement of intraocular pressure, applanation pneumatonography was used and tissue MAO activities were determined by radiometric assay. After topical administration with clorgyline, MAO-A activities in the bulbar conjunctiva and the iris-ciliary body were remarkably inhibited, whereas MAO-B inhibition was minimal. Maximal reduction of intraocular pressure with 0.05% epinephrine was 3.2 mmHg. Single administration of clorgyline, amiflamine, moclobemide or CGP 11305-A caused decreases in the intraocular pressure of 2.0, 2.5, 1.8 and 2.4 mmHg, respectively. In the coadministration experiments with epinephrine, the ocular hypotensive effects of epinephrine were potentiated with clorgyline, amiflamine, moclobemide and CGP 11305-A (6.6, 4.8, 5.6 and 5.8 mmHg). On the contrary, they were not influenced by the MAO-B inhibitor deprenyl. These results indicated that MAO-A inhibitors potentiated the ocular hypotensive effects of epinephrine, and that the coadministration of a reversible MAO-A inhibitor with epinephrine might be useful for patients with glaucoma.

Animals↗