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Biomedical subjects

M Iu Chuchin

Publications and source records attributed to M Iu Chuchin.

7 recordsLinked to original sources
PubMed2004

[Ischemic stroke in children].

Acute cerebral vascular pathology is considered to be an actual problem not only for adults but also for children. The data have been accumulating about a serious and non-rare brain disorder, namely acute disturbance of brain circulation, ischemic type. The long existed conception of a predominant role of intra-cerebral hemorrhages in children has also been changed that mirrored in world publications of the last years, mostly devoted to the problem of ischemic stroke.

Brain Ischemia↗
PubMed1993

[Spastic torticollis in children (the problems of the clinical picture, treatment and nosological specificity)].

Twenty-two cases with spastic torticollis in children are analyzed. This syndrome was the only suffering in ten children and was a component of generalized forms of deforming muscular dystonia in twelve. In such cases the time course of spastic torticollis clinical picture, possible alteration of tonic and clinical forms, involvement as a rule of hands and shoulders muscles permit regarding this condition as a variant of local deforming muscular dystonia and not an individual hyperkinesis. The efficacy of routine drug therapy administered to these patients directly depended on the form and pattern of spastic torticollis. Positive shifts were observed in 90.9% of patients, in 40.9% a marked positive effect was attained.

Adolescent↗
PubMed1991

[Myoclonus epilepsy in children and adolescents].

Twelve cases of myoclonus epilepsy initiating in childhood and adolescence were studied clinically, electrophysiologically and biochemically. Myoclonic and epileptic syndromes being most pronounced, the clinical pattern presented certain polymorphism: asymmetry, hyperkinesis, myodystonia, epileptic episodes, mental disorders. The electroencephalographic picture of the disease was variable. Hyperexcretion of glycosaminoglycans and changes in their fraction composition with predominant release of heparan sulphate evidenced for deranged metabolism of mucopolysaccharides.

Adolescent↗
PubMed1986

[The stiff man syndrome].

A 41-year-old patient with the rigidity syndrome was observed. The disease was expressed in marked rigidity of the long muscles of the back forming a picture of persistent hyperlordosis which led to a considerable disablement of the patient. Another complaint was spasms of the femoral muscles. A four-year follow-up of the patient revealed periodically recurring ataxia, nystagmus, and dysarthria. The patient benefited by relanium (diazepam) administration. On the basis of the literature data and a clinical analysis of this case the authors review clinical, differential-diagnostic, pathogenetic and etiological aspects of the rigidity syndrome.

Adult↗
PubMed1983

[Treatment of myotonia].

The results of sodium oxalate treatment undertaken in 25 patients with various forms of myotonias are presented. The beneficial effect of the drug is confirmed by the clinical, biochemical and electromyographic findings.

Adolescent↗
PubMed1982

[Electromyographic features of 3 forms of myotonia].

On the basis of a great body of examination data the electromyographic peculiarities of three forms of myotonia are analyzed. As a result, the authors come to a conclusion that in the third form of myotonia the function of muscular fibres is grossly impaired, this impairment following the pattern of their being put out of activity. This failure appears invariably during the muscle activity and leads, in the end to the clinically observed transient, and in more advanced cases, moderately permanent weakness of the muscles and their hypotrophy. In addition, data on synaptic apparatus involvement were also obtained. The time course of the development of those disorders, as regards the neuromuscular conduction and the distal parts of the muscular fibres is followed. In atrophic myotonia, certain peculiarities of the electrophysiological characteristics of the neuromuscular periphery were noted. In particular, a marked phase of secondary refractoriness was revealed. Thomsen's myotonia was found to differ substantially in the electrophysiological characteristics from the above two forms of the myotonia. Although in a number of cases it is difficult to class a particular case with one or another form of myotonia (this can be explained by an exceedingly great diversity of the biochemical peculiarities inherited by each individual) the differentiation of the above three forms of myotonia is justified from the viewpoint of both exploring the pathogenesis of the disease forms, and choosing the treatment method the most effective in this particular case. Of importance in solving these problems may be diversified electrophysiological examinations of the motor apparatus, and comparisons of their results with those of clinical examinations.

Adolescent↗