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Biomedical subjects

M Iusim

Publications and source records attributed to M Iusim.

7 recordsLinked to original sources
PubMed1992

Evaluation of the degree of effectiveness of biobeam low level narrow band light on the treatment of skin ulcers and delayed postoperative wound healing.

Twenty-one patients with 31 postoperative delayed open wounds resistant to conventional therapy were randomly allocated to three groups. Group 1 was treated with red low level narrow band (LLNB) light (660 nm); group 2 was treated with infrared LLNB light (940 nm); and group 3 was treated with a placebo such as the Biobeam machine (no light irradiation). Group 1 showed a significant improvement compared to groups 2 and 3 (t-test).

Aged↗
PubMed1987

Clinical assessment of Maquet tibial tuberosity advancement.

Advancement of the tibial tuberosity (TTA) or Maquet procedure is a controversial procedure. Between 1978 and 1982, 27 consecutive patients were treated by TTA with an average follow-up period of 5.5 years in 25 patients. In eleven cases with concomitant medical compartment osteoarthritis, TTA was combined with high tibial osteotomy (HTO). Patellar pain relief was noted soon after surgery and was sustained in 80% of the patients. Systemic complications included one patient with lethal pulmonary embolus. Local complications occurred as follows: three patients had severe local necrosis of skin, which required a rotation skin flap in two. In one patient, the bone graft displaced, and in two patients, nonunion of this graft was noted. Following appropriate treatment in these six patients their final rating was excellent in two, good in three, and poor in one. Contrary to other reports in the literature, the combination of HTO and TTA was as successful as the Maquet procedure alone. TTA is an important procedure for severe patellofemoral arthritis after all other methods of conservative treatment have been exhausted and no other surgical procedure is clearly indicated.

Adult↗
PubMed1985

Histologic pattern of biomechanic properties of the carbon fiber-augmented ligament tendon. A laboratory and clinical study.

Implantation of carbon fiber tow (CFT) for ligament and tendon augmentation was investigated in ten dogs and 45 patients. CFT produced a new structure with a remarkably consistent structural pattern. The basic pattern of the CFT-augmented unit consisted of a core of carbon fiber surround by concentric layers of fibroblasts and collagen fibers. This unit structure was developed from continuous irritation of physical structure of the carbon fiber. In dogs, ultimate tensile strength of the augmented tendon one year after surgery averaged 88% of natural tendon. Digestion of the connective tissue component of the CFT unit exposed the original carbon fiber tow. The connective tissue-free CFT maintained its original tensile strength. The continuous production of collagenous tissue surrounding carbon fibers produced a ligamentous structure that was physiologically compatible and biomechanically sufficient.

Animals↗
PubMedDate not supplied

Ligament and tendon substitution with composite carbon fiber strands.

Carbon fiber strands were used experimentally to substitute for tendons in dogs and clinically to reconstruct tendons and ligaments in human. The investigation was carried out to determine the histologic appearance of the new composite structure and its tensile strength in comparison to the natural structure. The histologic picture disclosed a remarkable structure evolved by continuous irritation of the carbon fibers and consisting of two interrelated components: synthetic carbon fibers and biologic collagenous tissue. This carbon fiber composite structure was composed of long cylindrical units containing concentric layers of collagenous fibers and cells enveloping the core of each carbon fiber. After one year of physiologic use in dogs, the average ultimate tensile strength of the composite structure which replaced the quadriceps and triceps was 372 N, or 88% the strength of the natural tendons. One year after implantation the histologic picture of the composite structure in human showed a relatively dense collagenous architecture. However, a significant proportion of the structure was taken up by histiofibroblasts produced by the irritation of the carbon fibers. Thus, the density of the collagen in the composite structure remained relatively deficient in comparison to the nature tendon, and the structural tensile strength continued to depend entirely on the integrity of the carbon fibers.

Animals↗