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Biomedical subjects

M Iwasawa

Publications and source records attributed to M Iwasawa.

28 records · Page 2Linked to original sources
PubMed1992

[Reconstruction of anterior cranial base and face with free musculocutaneous flap; report of two cases].

The treatment of extensive cranial base tumor is still challenging. Wide resection of a cranial base tumor would lead to exposure of the vital structures such as the brain and dura, and would result in a large dead space in the cranium and in the connecting area between the nasal cavity and the intracranial space. Recently free tissue transfer has become a reliable method in the field of reconstructive surgery. In the craniofacial region, free tissue transfer is useful to reconstruct a complicated defect. We report two cases where free latissimus dorsi M-C flap and rectus abdominis M-C flap were useful in reconstructing the defect following removal of an anterior cranial base tumor. We discuss the advantages.

Aged↗
PubMed1991

Congenital curved nail of the fourth toe.

Five cases of congenital curved nail of the fourth toe are reported. Patients included four males and one female; four cases were bilateral, and one was unilateral. There were no other significant associated anomalies of the extremities, and only the fourth toes were affected. The features of the deformity are a curved nail and hypoplasia of the soft tissue and bone of the distal phalanx of the fourth toe. This anomaly may be transmitted autosomally and is unique in that it may be of mesodermic origin.

Child↗
PubMed1990

[Clinical study of penile cancer].

Recent progress in molecular biology suggests a certain relationship between penile cancer and human papilloma virus infection. However, the treatment for penile cancer has not been established since each institute has experienced only a small number of patients. We analyzed the result of our treatment for 14 penile cancer patients during past twenty years. Ten of the 14 patients were initially treated for the primary lesion with a combination of peplomycin (PEP) or bleomycin (BLM) and radiation therapy. Of these, 9 were found not to have residual viable cancer cells in their primary lesions. No local recurrence was found in all 7 patients in whom the penis was preserved. This result suggests that combination of PEP (BLM) and radiation preserves the penis without increasing the risk of local recurrence. Penile cancer-related death did not occur in patients without lymph node metastasis. However, this cancer death did occur in 4 out of 7 patients with lymph node metastasis, suggesting that metastasis is one of the important prognostic factors. PEP (BLM) and radiation therapy with or without regional lymph node dissection did not improve the prognosis of patients with advanced penile carcinoma, such as with pN2, pN3 or distant metastasis. More effective management may be necessary for these patients.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1989

Improvement in the surgical results of treatment of duplicated thumb by preoperative splinting.

Seven patients with an angular deformity of their duplicated thumb were treated by splinting and taping before operation. In all patients, the angular deformity of the interphalangeal joint improved within a few months, and surgical centralization and osteotomy were not necessary. Furthermore the design of the fillet flap was easier and more accurate as was the adjustment of the joint ligament tension. After operation there was no recurrence of angular deformity, and the range of motion of the interphalangeal joint was good. We believe that this procedure simplifies the operative approach, making it more precise and helping to prevent postoperative complications in patients with angular deformity.

Hand Deformities, Congenital↗
PubMed1987

Lower eyelid reconstruction with a conchal cartilage graft.

A conchal cartilage graft without skin or mucosa was used as a posterior lining for lower eyelid reconstruction in seven patients. The raw surface of the graft was smooth enough to cause no corneal irritation and was epithelialized from the surrounding mucosa about 3 to 4 weeks after the operation. The lower eyelid reconstructed in this method produced a stable lid margin.

Adult↗
PubMed1985

Cryptotia: our classification and treatment.

Our classification of cryptotia is based on recognition that the deformity is the result of an anomaly of the intrinsic transverse and oblique auricular muscles. Our treatment, in the first instance, is a non-surgical correction. This should be started early, if possible in the first 6 months of the baby's life. Even in the case of older children, success can sometimes be achieved and a non-surgical correction should be considered first. If non-surgical management fails the deformity can be corrected surgically by dividing the muscle fibres that produce the anomaly of the external ear through a small incision. Our new surgical approach involves moving the available skin in the region of the inferior cephalo-auricular sulcus to the superior part where skin is needed by a rotation flap. This operation has several advantages.

Age Factors↗
PubMedDate not supplied

Reverse flow fillet flap from a supernumerary finger.

We report a new technique for making a fillet flap from a supernumerary finger in three cases. These flaps are unique in possessing retrograde blood flow or both orthograde and retrograde blood flow and have a wider arc of rotation than provided by conventional methods. This technique permits one to design more freely. We believe this concept is also applicable to repairing other anomalies of the hand in situations where standard methods are not effective.

Female↗
PubMedDate not supplied

Conservative management for perimenopausal women with uterine leiomyomas using Chinese herbal medicines and synthetic analogs of gonadotropin-releasing hormone.

The effects of a long-term intranasal administration of each of the gonadotropin-releasing hormone analogs, buserelin and nafarelin on uterine leiomyomas after conservative treatment using Chinese herbal medicines, Keishi-bukuryo-gan and Shakuyaku-kanzo-to were investigated in 30 perimenopausal women with leiomyomas. Hypermenorrhea and/or dysmenorrhea as a chief complaint was moderately improved by the treatment using Chinese herbal medicines in more than 60% of the patients with less than fist-sized leiomyomas, but not the over fist-sized. Afterwards, continuous treatment using analogs produced a long-term reduction in leiomyomas (less than 60%) along with decreases in the serum levels of luteinizing hormone, follicle-stimulating hormone, estradiol, and the tumor marker CA-125, and adverse effects including slight boneloss. Long-term treatment using Chinese herbal medicines and gonadotropin-releasing hormone analogs for the management of uterine leiomyomas could be beneficial for patients a few years before menopause, though possible side effects of this treatment should be monitored.

Adult↗