PubMed Health⌕ Search

Biomedical subjects

M J Balsdon

Publications and source records attributed to M J Balsdon.

18 recordsLinked to original sources
PubMed1994

[Human immunodeficiency virus (HIV) infection in obstetrics and gynaecology].

HIV infection is increasingly affecting the practice of obstetrics and gynaecology. Gynaecological problems include an increased risk of sexually transmitted diseases and other genital infections in HIV positive women. Also cervical neoplasia is more common, more severe and progresses more rapidly. The risk of infection to the surgeon during surgical procedures on HIV positive women can be minimized by simple universal precautions. Pregnancy does not affect the course of HIV infection and neither is routine management of antenatal care altered by the infection. However, routine testing of all pregnant women for HIV would enable reduction of the risk of vertical transmission of HIV to the fetus (in Chile about 25%). Levels of vertical transmission could be reduced substantially by using zidovudine in pregnancy (and in the neonate), by cesarean section before active labour and by not breast feeding.

Acquired Immunodeficiency Syndrome↗
PubMed1988

Recurrent vaginal candidosis: prospective study of effectiveness of maintenance miconazole treatment.

In a prospective study, 100 women with recurrent vaginal candidosis were treated with miconazole, using two 100 mg vaginal pessaries a day for one week, then one pessary twice a week for three months followed by one pessary a week for a further three months. Fifty four women elected to continue using one pessary a week for longer than six months. Symptomatic vaginal candidosis did not occur in any patient during regular maintenance treatment. Of the 46 women who discontinued treatment before six months, however, 22 had a recurrence. Maintenance prophylactic treatment with miconazole pessaries appears to be an acceptable and effective method of preventing recurrent episodes of vaginal candidosis.

Adolescent↗
PubMed1983

Treatment of the Gardnerella vaginalis syndrome with a single 2 gram oral dosage of metronidazole.

The Gardnerella vaginalis syndrome (GVS) is characterized by a smelly vaginal discharge of pH greater than 5.2. The microscopic appearance of the discharge is diagnostic. The Gram stain shows masses of small Gram variable bacilli which have a 'pepper and salt' pattern, and the wet film 'clue cells' and 'rafts' (floating clumps of small bacilli). The amine test is an additional diagnostic aid. 30 patients with this syndrome were treated with 2 g of metronidazole in a single oral dosage. 29 patients were cured at one week and 2 patients had a recurrence four weeks later.

Administration, Oral↗
PubMed1982

Gardnerella vaginalis and its clinical syndrome.

The Gardnerella vaginalis syndrome is a well defined but benign condition characterized by a smelly vaginal discharge of pH greater than 5.0. It is not associated with inflammation. It often occurs in association with cervical infections. The microscopic appearance of the discharge is typical and diagnostic. The wet mount shows "clue cells" and "rafts" (floating clumps of small bacilli) and the Gram stain has the "pepper on salt" pattern of masses of small gram-variable bacilli. The amine test is an additional diagnostic aid. Cultures are useful but not necessary for diagnosis. The treatment of choice is oral metronidazole 400 mg twice daily for five days.

Amoxicillin↗
PubMed1981

Comparison of miconazole-coated tampons with clotrimazole vaginal tablets in the treatment of vaginal candidosis.

The effectiveness and acceptability of miconazole-coated tampons were compared with those clotrimazole vaginal tablets in the treatment of vaginal candidosis in 100 women. Both treatments were highly effective in reducing the signs and symptoms of infection; 95% of the group treated with miconazole had negative culture results for Candida species immediately after treatment compared with 86% of those treated with clotrimazole. A 17.6% recurrence rate of positive culture results was found four weeks later in the miconazole-treated group compared with that of 30% in the clotrimazole-treated group. The miconazole tampons were highly acceptable to patients. Vaginal pH values did not differ significantly between those patients with candidosis and those treated and cured. Corynebacterium vaginale (Gardnerella vaginalis) vaginitis and nonspecific genital infection were common complicating factors during follow up.

Adolescent↗
PubMed1980

Corynebacterium vaginale and vaginitis: a controlled trial of treatment.

In a study of the diagnosis and treatment of Corynebacterium vaginale (Haemophilus vaginalis) vaginitis in 30 patients, clinical and microscopical findings were compared with laboratory cultures. The study also included a double-blind randomised trial of treatment regimens including placebo therapy. Laboratory cultures of C. vaginale corresponded well with clinical findings, and we suggest that C. vaginale vaginitis can be reliably diagnosed with clinical and microscopical findings. Tetracycline was effective in half the patients treated, whereas all but 1 of the 17 patients eventually treated with metronidazole were cured. The apparent discrepancy between in-vitro sensitivity and in-vitro efficacy of metronidazole in this condition is discussed.

Adolescent↗
PubMed1979

Rapid staining technique for Trichomonas vaginalis. Preliminary report.

A simple, rapid, staining method for the identification of Trichomonas vaginalis has been tested on cultured trichomonads and specimens of vaginal discharge. Fifty-eight stained slides of vaginal discharge were examined and trichomonads were correctly identified in the 31 specimens from patients with confirmed vaginal trichomoniasis. No false-positive results were obtained. This staining procedure could prove a useful addition to wet-film and cultural methods.

Adolescent↗
PubMed1978

A survey of attitudes of patients in a department of genitourinary medicine.

A questionnaire concerning clinic organisation was completed by 415 patients attending a department of genitourinary medicine. Most (62.9%) patients preferred to be identified by number rather than by name, and about half (52.7%) did not like mixed waiting rooms. An appointment system as well as having an open clinic was liked by twice as many (44.9%) as those patients (23.6%) against such a system. More information about sexually transmitted diseases in the form of leaflets, etc. at the clinic was requested by most (79.1%) patients and a similar number (82.0%) felt the department itself should be more widely advertised.

Adult↗