Increased release of dopane from striatal dopaminergic terminals in the rat after treatment with a neuroleptic: thioproperazine.
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Amphetamine↗
Biomedical subjects
M J Besson
Publications and source records attributed to M J Besson.
[Study of the regulation of the limitating stage of dopamine biosynthesis at the level of the rat striatum].
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Animals↗
Effects of amphetamine and desmethylimipramine on amines synthesis and release in central catecholamine-containing neurons.
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Amphetamine↗
Release of newly synthesized dopamine from dopamine-containing terminals in the striatum of the rat.
The extraneuronal spontaneous efflux of (3)H-dopamine synthesized endogenously in dopamine terminals has been demonstrated in vitro, by collecting the (3)H amine in superfusates of isolated striatum of the rat previously incubated with (3)H-tyrosine. The (3)H-dopamine newly synthesized appears to be preferentially released. Furthermore, amphetamine and a monoamine oxidase inhibitor (Carton) markedly increased the release of (3)H-dopamine. This effect was also observed with substances normally contained in some striatal neurons: acetylcholine and 5-hydroxytryptamine.
Acetylcholine↗
[Demonstration of the liberation of dopamine (DA) and serotonin (5HT) at the caudate nucleus level in the rat].
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Animals↗