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Biomedical subjects

M J Bowman

Publications and source records attributed to M J Bowman.

5 recordsLinked to original sources
PubMed1984

Thyroid hormone-induced precocious growth and maturation of the embryonic chicken liver.

The effects of thyroid hormones thyroxine (T4) or triiodothyronine (T3) on the ontogeny of chicken embryonic liver were studied. Two micrograms of T4 administered to chicken embryos, prior to day 11 of incubation, was found to be least toxic and effective in increasing liver weights, total protein and DNA and RNA, over those of controls. A non-toxic dose of T4 (0.1 microgram) had no effect on embryonic chicken liver. Injection of 125I-labelled T4 or T3 into chick embryos showed that T4 was taken up in greater amounts by the liver than was T3. Uptake of both hormones by the liver increased dramatically around day 9 of incubation. Induction of hypothyroidism by methimazole (a goitrogen) suppressed the natural increase in liver weight.

Animals↗
PubMed1978

Age disorientation in schizophrenia: a constant prevalence of 25 per cent in a chronic mental hospital population?

The prevalence of age disorientation was estimated in the population of patients with a diagnosis of schizophrenia in a large mental hospital. Of these 357 patients 25 per cent demonstrated age disorientation, defined as a five-year discrepancy between true and subjective age, and 11 per cent of the population believed themselves to be within five years of the age they were at admission, although they were a mean 28.9 years older. Age-disorientated patients differed from the age-orientated in being significantly older. However, when age-matched, they were younger at first admission and had a longer duration of stay than patients with a diagnosis of schizophrenia without age-disorientation. Age-disorientation may thus be a feature of a type of schizophrenic illness of early onset and poor prognosis.

Adult↗
PubMed1977

A clinic within a general hospital for the assessment of urgent psychiatric problems.

Of 100 consecutive referrals to a clinic for urgent psychiatric assessment only a third (34 patients) were considered to warrant such urgent attention. In 29 of the 34 cases the patient's behaviour--either intent to harm himself or unpredictable behaviour that alarmed the referring agent--was the most important consideration for urgent assessment.

Emergency Service, Hospital↗