Biomedical subjects

M J Brune

Publications and source records attributed to M J Brune.

2 recordsLinked to original sources

PubMed1981

Point estimates of concentrations by simple immunoassays.

Point estimates can be generated by simple immunoassays when combined with a sequential statistical procedure. The method is called an extended simple immunoassay. A simple immunoassay for alpha-fetoprotein (counterimmunoelectrophoresis) was used to test the hypothesis that simple immunoassays are not restricted to qualitative "yet" or "no" results, but can provide quantitative results similar to radioimmunoassay. Potential benefits of this finding are discussed.

Counterimmunoelectrophoresis↗

PubMed1978

Cerebrospinal fluid myelin basic protein and multiple sclerosis.

We have previously reported that myelin basic protein appears in CSF during acute attacks of multiple sclerosis. These studies have been extended to over 700 patients, 91 with multiple sclerosis. The data continues to indicate that myelin basic protein is released into cerebrospinal fluid during acute attacks of multiple sclerosis. We are currently characterizing the basic protein in the CSF.

Acute Disease↗