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Biomedical subjects

M J Dobrogowski

Publications and source records attributed to M J Dobrogowski.

3 recordsLinked to original sources

A new glaucoma filter implant.

A new glaucoma filtration procedure was performed in nine rabbits in a preliminary trial. A silastic tube with an internal diameter of 0.35 mm was passed across the anterior chamber through two limbal openings, and the free ends were buried postequatorially in sub-Tenon's space. At a later date, using an Nd:YAG laser in the thermal mode, holes 0.05 to 0.30 mm in diameter were burned in the tube in the anterior chamber. This procedure significantly lowered intraocular pressure in four rabbits on two successive tries; however, a third treatment given in two cases did not further decrease the pressure.

Animals↗

Contact lens disinfection by ultraviolet light.

A 253.7-nm ultraviolet light with an intensity of 1,100 microW/cm2 was tested for its germicidal activity against contact lenses and storage solutions contaminated with various corneal pathogens. The exposure time necessary to reduce a concentration of organisms from 10(6)/ml to less than 10/ml was 30 seconds for Staphylococcus aureus, 60 seconds for Pseudomonas aeruginosa, and 84 seconds for Candida albicans. The time necessary to sterilize a suspension of 10(4)/ml Acanthamoeba polyphaga was less than three minutes with this technique. Four brands of soft contact lenses were exposed to ultraviolet light for over eight hours without changing their appearance, comfort, or refraction.

Acanthamoeba↗