PubMed Health⌕ Search

Biomedical subjects

M J Duddy

Publications and source records attributed to M J Duddy.

13 recordsLinked to original sources
PubMed2003

Central pontine myelinolysis complicating treatment of multicentric Castleman's disease and Kaposi's sarcoma in a patient with AIDS.

An HIV positive black African woman presented with widespread lymphadenopathy and pancytopenia that had been ascribed to tuberculosis. Lymph node biopsy showed both Kaposi's sarcoma and multicentric Castleman's disease. Despite antiretroviral therapy and chemotherapy the patient deteriorated, developing confusion and dysphasia. A cranial magnetic resonance scan showed central pontine myelinolysis. Despite supportive therapy the patient died.

AIDS-Related Complex↗
PubMed2002

Progressive intrathoracic lymphadenopathy: EBV associated non-Hodgkin's lymphoma.

A 30 year old man presented with late stage HIV disease and intrathoracic lymphadenopathy. Histology of a mediastinal biopsy suggested infective follicular hyperplasia or a peripheral T cell lymphoma. Subsequently, Epstein-Barr virus (EBV) infection was demonstrated in lymphocytes in the biopsy. Later, hepatosplenomegaly and peripheral lymphadenopathy developed. Histology of a cervical lymph node biopsy showed EBV associated diffuse large B cell (non-Hodgkin's) lymphoma.

AIDS-Related Opportunistic Infections↗
PubMed1998

Safety standards for stab-resistant body armour: a computer tomographic assessment of organ to skin distances.

The protective properties of knife-resistant armour are quantified by the distance a test blade penetrates beyond a test sample into clay at a given energy. At present there are two proposed standards: penetration to 5 mm and penetration to 20 mm. Armour made to the higher standard specification (5mm) is necessarily heavier as it offers more protection. To determine the safety of these standards a retrospective review of 71 consecutive computerised tomographic (CT) scans was made. The minimum distance from the skin to the vital organs was measured. No organ would have been breached at 5 mm of knife penetration deep to body armour. 41% of pleurae, 61% of livers, 64% of femoral arteries, 25% of spleens and 6% of hearts would have been breached at a depth of 20 m of knife penetration. There was no significant difference in the minimum skin to organ distances between male and female subjects. The 20 mm standard does not offer adequate protection against knife attacks.

Adult↗
PubMed1993

Case report: rhabdomyolysis following grand mal seizures presenting as a delayed and increasingly dense nephrogram.

Rhabdomyolysis as a result of major trauma is a well recognized cause of acute renal failure. Non-traumatic rhabdomyolysis causing transient renal impairment may occur following generalized convulsions. We present a case in which rhabdomyolysis following epilepsy was first indicated at urography by a delayed and increasingly dense persistent nephrogram.

Acute Kidney Injury↗
PubMed1991

Duplex ultrasound of the common femoral vein in pregnancy and puerperium.

The common femoral veins of 34 apparently normal women were examined by ultrasound during or just after pregnancy. The cross sectional areas of these veins were measured at rest in the supine position and during a Valsalva manoeuvre. The veins were also assessed by pulsed Doppler ultrasound. We believe that Doppler examination is superior to calibre response assessment during the Valsalva manoeuvre in excluding an isolated iliac occlusion in women in late pregnancy and in early puerperium.

Female↗
PubMed1991

Hindbrain migration after decompression for hindbrain hernia: a quantitative assessment using MRI.

Pre- and post-operative assessments are presented in 17 adult patients who have been treated with craniovertebral decompression for hindbrain herniation, 11 of whom had syringomyelia. Objective improvement in the size of the syrinx was seen in all 11 cases; contrary to expectation the hindbrain more frequently moved downwards than upwards after decompression of the tonsils and creation of an artificial cisterna magna. A method is reported for the quantitative assessment of hindbrain migration using magnetic resonance imaging (MRI). The degree of 'slump', further downward displacement of the hindbrain, was compared with the clinical outcome and the MRI appearances. Slump was more common than expected, although the severity was not usually great enough to produce symptoms. Slump was less marked where the artificial cisterna magna was generous (p less than 0.02). This quantitative method may be useful in assessing patients with unexplained post-operative symptoms and in comparing different surgical techniques.

Adolescent↗
PubMed1990

Injection rate: a factor in contrast reactions?

A prospective study comparing the frequency of contrast reactions by the rate of contrast injection is presented. One hundred patients undergoing excretion urography with meglumine diatriazoate (18%) and sodium diatriazoate (40%) mixture (Urografin 325) were randomised into slow (mean 0.975 ml/s) and rapid (mean 2.575 ml/s) injection groups. In the slow injection group 6 (12%) patients experienced a significant reaction as compared with 4 (8%) in the rapid injection group. There was no significant relationship between injection rate and contrast reaction (P greater than 0.1).

Adult↗