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Biomedical subjects

M J Faer

Publications and source records attributed to M J Faer.

7 recordsLinked to original sources

Management of the fetus with a urinary tract malformation.

Obstetric sonography revealed urinary tract malformations in 13 fetuses. Six had severe dysplastic lesions incompatible with postnatal life; in all six, oligohydramnios and inability to detect normal kidney or bladder allowed appropriate counseling and management. Four fetuses had unilateral lesions (three hydronephrotic, one multicystic); all had evidence of adequate contralateral function and were successfully treated after delivery near term. Three fetuses had bilateral hydronephrosis secondary to urethral obstruction. The two who were born near term died of hypoplastic lungs, end-stage hydronephrosis, and facial and skeletal deformities. The other, electively delivered at 32 weeks, had none of the stigmata of Potter's syndrome, and early decompression salvaged sufficient renal function for survival. Prenatal sonographic assessment of urinary tract anatomy and function can improve perinatal management. The fetus with hydronephrosis may benefit from early decompression.

Abnormalities, Multiple↗

Traumatic splenic cyst: radiologic-pathologic correlation from the Armed Forces Institute of Pathology.

Traumatic splenic cyst is one of many diagnostic choices when a mass is found in the left upper quadrant. In the appropriate clinical setting, demonstration of an intrasplenic, unilocular, avascular, homogeneous, fluid-filled mass with a smooth, sharply marginated wall should suggest a splenic cyst. On pathological examination, an epithelial lining implies a developmental origin. More commonly, no such lining is found and old trauma is assumed to be the etiology.

Cysts↗

Inferior vena cava duplication: demonstration by computed tomography.

Two cases demonstrating the computed tomographic (CT) appearance of inferior vena cava (IVC) duplication are presented, and the embryological, clinical, and radiological significance are discussed. Knowledge of caval anomalies can prevent misinterpretation of mediastinal masses, iliac occlusion with venous collaterals, or paravertebral lymph node enlargement. A duplicated IVC can be distinguished from para-aortic lymphadenopathy either by recognition of renal vein drainage or through intravenous contrast enhancement of the venae cavae.

Adult↗

Mycotic aortic aneurysm in premature infants.

Three cases of aortic aneurysm adjacent to the tip of the umbilical artery catheter are described. The clinical presentation, radiographic findings, and proposed pathogenesis are discussed. Mycotic aneurysms in childhood are infrequent but serious threats to life, requiring early recognition and prompt therapy. The appearance of a progressively enlarging middle or posterior mediastinal mass in a child with a history of septicemia should suggest a mycotic aneurysm.

Aneurysm, Infected↗

Cerebral granulomatous angiitis: case report and literature review.

Granulomatous angiitis is a pathologically distinct central nervous system segmental vasculitis of unknown etiology and pathogenesis which may be indirectly related to herpes zoster infections. The condition primarily affects adults and presents with nonspecific, unexplained progressive neurological dysfunction. The cerebrospinal fluid is often under increased pressure and contains excess protein and white cells, mostly lymphocytes. The necrotizing vasculitis primarily affects the small intracranial arteries and veins and alters vascular permeability, ind,cing cerebral edema. Angiography demonstrates segmental, diffuse, distal vascular irregularity and narrowing, while computed tomography shows poorly defined, diffuse, non-contrast-enhancing low density areas with or without mass effect. In the approprite clinical setting, the angiographic and CT findings should be highly suggestive. The possibility of efficious therapeutic intervention makes early diagnosis important. CT can also be used to monitor therapeutic response.

Aged↗