Acceleration by calcium of the inactivation of thrombin by plasma proteinase inhibitors.
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Biomedical subjects
Publications and source records attributed to M J Griffith.
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It is feared by many doctors that teaching basic life support (BLS) to high risk cardiac patients or a member of the family increases their anxiety. We trained a group of patients with recurrent ventricular tachycardia in BLS together with a friend or family member. Measurement of anxiety before and three months after training demonstrated a reduction in anxiety in both groups. This suggests that basic life support training can be targeted to high risk groups without fear of increasing anxiety.
When new patients join a prepaid group practice, their utilization of services is usually higher than it will be in a year or so. This "start-up effect" must be considered when planning for group growth. Demand projections are commonly based on data from outside sources and often fail to consider the many critical implications of the start-up effect. More accurate planning can be accomplished by using concrete start-up analysis based on internal information. Administrators who use careful predictions of demand levels rather than guess-work in their planning will provide their organizations with the foundation for a sound system of dynamic growth management.
Five hundred and forty-seven total hip replacements by the Charnley technique during 1967 and 1968 have been studied for the quality of the late results. The average follow-up was 8.3 years. Mechanical failure at the cement-bone interface occurred in only 2.2% of cases. A search was specially directed towards evidence of incipient pathology at the bone-cement interface in the absence of any suspicion of clinical defect. This was found in 12% of cases but it is emphasized that the criteria were exceptionally rigorous and entirely radiological. Because the cement technology used at that time is now considered unsophisticated, mechanical failure of cement is a preventable condition. A previous report of socket migration in 9.5% of cases is not confirmed by the present survey of a more recent series of cases.
Five hundred forty-seven Charnley hip arthroplasties were measured for wear radiographically after an average period of 8.3 years. The operations were performed in 1967 and 1968 and the average rate of wear was 0.07 mm per year. This is only half that recorded for the operations in 1963, 1964, and 1965. Clinical radiographic methods of measuring socket wear are valid provided that the socket is inserted with the wear marker not more than 10 degrees from the coronal plane. This can be estimated provided that radiopaque cement is used.