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Biomedical subjects

M J Joubert

Publications and source records attributed to M J Joubert.

9 recordsLinked to original sources
PubMed1985

Neurocysticercosis--a comprehensive approach to medical treatment.

The incidence of cysticercosis in South Africa may well be alarming. Cysticercosis of the central nervous system (CNS) is almost exclusively confined to the parenchyma of the brain. Before the introduction of computed tomography (CT), invasion of the CNS by the parasite could only be suspected on the basis of evidence of previous infestation. The use of praziquantel in the treatment of cysticercosis is a major step towards eradicating the disease, but to be effective treatment must take cognizance of reinfection, the allergic reaction caused by the dying parasites, and the possible need for repeated courses of treatment. The therapeutic regimen is outlined and the efficacy of the treatment as monitored by CT evaluated.

Adult↗
PubMed1981

Neurofibromas of the spine -- a pathognomonic sign.

Neurofibromas growing from spinal nerve roots commonly cause enlargement of the intervertebral foramen. The enlargement is occasionally minimal if the bulk of the tumour is outside the spinal canal, in which case there is widening of the gap between the zygapophyseal joints and transverse processes of adjacent vertebrae seen on anteroposterior projection. This sign is regarded as pathognomonic of neurofibroma.

Humans↗
PubMed1977

Computerized tomography and surgical treatment in intracranial suppuration. Report of 30 consecutive unselected cases of brain abscess and subdural empyema.

The authors report their experience with 30 cases of intracranial suppuration: 23 with brain abscess and seven with subdural empyema. All of the cases were diagnosed by means of computerized tomography and enhancement with intravenous contrast material. Most of the patients were treated by single or repeated aspiration through burr holes.

Brain Abscess↗
PubMed1976

Computerised axial tomography.

Computerised axial tomography has made an impressive impact on surgical neurology, and when the body scanner becomes available it will no doubt have similar advantages for the other specialities. It is a safe non-invasive method of investigating pathological processes of the brain. The amount of information so obtained is accurate to within 1% and at least a hundred times more inforation is obtained than from ordinary X-ray investigations. A review of 1 000 patients scanned is presented. Computerised axial tomography, if artefacts are eliminated completely, is most unlikely to yield a false positive scan. Its greatest value, however, is in the diagnosis of lesions in patients with head injuries and abscesses because these patients are very often moribund, and angiography, even when done expertly, may aggravate the clinical condition. Orbital and retro-orbital tumours have proved to be difficult to display other than by the EMI scanner methods. Acoustic neurinomata and meningiomata are also displayed with clarity, but owing to 'overshoot' artefact, other lesions, which do not enhance to the same extent on injection of Conray or Urografin, still offer a diagnostic problem. The investigation of epileptic patients has proved disappointing for the same reason that artefact obscures the low temporal lobe cut.

Brain Abscess↗