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Biomedical subjects

M J Killingback

Publications and source records attributed to M J Killingback.

8 recordsLinked to original sources

Hemoccult II test: routine screening procedure for colorectal neoplasm?

In October, 1978, the Hemoccult II Test was introduced as a screening procedure by the Sydney Hospital Heath Information and Screening Service. In the first two years, 4498 people were screened and 150 positive results were obtained. These people were referred for further investigation, with 114 choosing to attend the Edward Wilson Colon and Rectum Unit outpatient clinic at Sydney Hospital. Forty-four patients were found to have 59 colorectal neoplasms of which 13 were carcinomas. This represents a cancer incidence of 0.29% and corroborates the results of similar studies conducted overseas.

Australia↗

Irradiation injuries of the large intestine.

A series of 15 patients suffering from irradiation injuries to the large bowel is reviewed. Ten patients required surgical intervention, initially a diverting stoma in eight; intestinal continuity was re-established in three patients. Loop ileostomy may be preferable to loop transverse colostomy for fecal diversion, as the former is easier for the patient to manage, and ensures that there is no interference with blood supply to the colon should an abdomino-anal pull-through procedure be indicated later to restore continuity. As only three of the patients developed recurrent carcinoma, the initial operation for irradiation injury to the large bowel should be carefully planned so that the patient is not ultimately cured of carcinoma but left with a permanent stoma.

Aged↗

Prophylactic administration of low-dose heparin in colorectal surgery.

A retrospective study of 192 patients operated on by three members of the Edward Wilson Colon and Rectum Unit, Sydney Hospital, was carried out. All operations performed involved dissection within the pelvis. Prophylactic administration of low-dose heparin was used for 71 of these patients. The incidences of clinical thromboembolic disease were 7 per cent in both the group receiving heparin and the other group. In slightly more than half of the patients, pulmonary emboli occurred in the absence of peripheral deep venous thrombosis. It is suggested that the source of these emboli was thrombosis arising in the pelvic veins.

Colon↗