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Biomedical subjects

M J MARMER

Publications and source records attributed to M J MARMER.

16 recordsLinked to original sources
PubMed1959

A barbiturate antidote. Use of methylethyl-glutarmide in barbiturate intoxication and in terminating barbiturate anesthesia.

Methylethylglutarimide was administered to 488 patients ranging in age from 7 to 89 years, in a study on sleep-reversal after harbiturate anesthesia. Sodium surital or sodium pentothal were the barbiturates used. The drug was administered intravenously in doses varying from 25 to 200 mg. Dosage below 25 mg. was found to be ineffective. Almost all patients showed signs of awakening as evidenced by the return of corneal and conjunctival reflexes, the opening of the eyes, and stirring or moving about. Many responded to questioning. Almost all showed evidence of greater responsiveness within five minutes. No untoward reactions were noted. No convulsions were produced. Five patients ranging in age from 24 to 70 years were treated for barbiturate poisoning with Mikedimide(R) given intravenously in doses varying from 550 mg. to 1950 mg. All recovered consciousness within 30 minutes to an hour. No convulsions were produced. While it is not known whether Mikedimide is a direct barbiturate antagonist, or whether it is an analeptic, it appears to be a useful drug in reversing the respiratory depression and the cerebral depression produced by harbiturate intoxication and barbiturate anesthesia.

Anesthesia↗
PubMed1957

Postoperative-postanesthetic recovery rooms; a report on three years of experience.

An analysis of the three-year experience of the recovery room at the Cedars of Lebanon Hospital emphasized the importance of this phase of postoperative care. Closer observation and supervision of the patient is provided during a critical period, and specialized nursing care is constantly available. Supportive and corrective therapy can be carried out immediately by the cooperative efforts of the anesthesiologist and surgeon, who are close by. The completely equipped and properly staffed recovery room is the best assurance for reducing postoperative morbidity and mortality.

Humans↗