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Biomedical subjects

M J McMillan

Publications and source records attributed to M J McMillan.

5 recordsLinked to original sources
PubMed1989

Premenstrual depression in women with a history of affective disorder: mood and attentional processes.

Survey studies have pinpointed high concordance rates between affective disorder and premenstrual depression. This relationship was investigated in women with a history of both disorders. Sixteen subjects rated symptoms daily during one menstrual cycle, and were assessed on measures of mood and selective attention pre- and postmenstrually. Prospective ratings confirmed premenstrual depression in only eight of the subjects. These subjects demonstrated a significant premenstrual elevation in dysphoric affect, yet exhibited a dysphoric attentional bias both pre- and postmenstrually. These data do not suggest an interactive relationship between affective disorder and premenstrual depression along the particular cognitive dimension of study.

Adult↗
PubMed1984

Consequences of nonverbal expression of pain: patient distress and observer concern.

Two studies examined the effects on others of nonverbal expressiveness of pain. Subjects viewed one of three videotapes of a simulated doctor-patient interview, with identical verbal content but different levels of expressiveness, and then completed a rating form. In Study I subjects were 44 senior nursing students. High nonverbal expressiveness yielded significantly higher ratings of patient pain and distress and observer concern. These variables also were inversely related to amount of nursing experience. Expressiveness had no significant effects on psychological support or nursing aids recommended for the patient. In Study II, 88 female undergraduates were categorized as low, medium or high on a measure of their need to nurture others. Irrespective of nurturance, ratings of patient distress, but not pain, were significantly higher in the high expressive condition. Nonverbal expressiveness of pain appears to influence ratings of the patient's affective state (distress) and the observer's affective response (concern).

Emotions↗
PubMed1978

Evidence for autonomous secretion of prolactin in some alcoholic men with cirrhosis and gynecomastia.

Prolactin responses to provocative thyrotropin releasing hormone (TRH) stimulation were evaluated in 20 cirrhotic men with gynecomastia. Fifteen of these cirrhotic men had normal responses with a minimum doubling of the prolactin concentration above basal in response to TRH. Five had abnormal (autonomous) responses in that they failed to double their basal level or had a paradoxical decrease from basal in response to TRH. Moreover, these same five men failed to have a sleep-related increase in plasma prolactin. Three of them also failed to respond to chlorpromazine stimulation. Such abnormal responses are generally associated with the presence of a prolactin secreting pituitary tumor. Basal plasma levels of prolactin were measured in all 20 men studied. The five men who failed to respond to TRH had significantly greater basal prolactin concentrations (80.5 +/- 18.7 ng/ml) than did the 15 men who responded normally (33.7 +/- 4.3 ng/ml) (p less than 0.01), although all 20 had increased prolactin levels relative to that of controls (10.8 +/- 0.9 ng/ml) (both p less than 0.01).

Gynecomastia↗