Biomedical subjects

M J Miller-Meeks

Publications and source records attributed to M J Miller-Meeks.

5 recordsLinked to original sources

PubMed1999

Driving simulation study: bilateral array multifocal versus bilateral AMO monofocal intraocular lenses.

PURPOSE: To determine whether differences exist in the driving performance of patients with bilateral Array multifocal intraocular lenses (IOLs) and those with bilateral AMO monofocal IOLs under low-contrast environmental conditions. SETTING: The Iowa Driving Simulator at the Center for Computer Aided Design, the University of Iowa, Iowa City, Iowa, USA. METHODS: This prospective study was a test-operator-masked, parallel-group comparison of the driving performance of 33 bilateral multifocal IOL patients and 33 bilateral monofocal IOL patients from the U.S. Array Multifocal study. Driving performance was evaluated under 3 poor visibility conditions (clear weather at night, clear weather at night in the presence of a glare source, and fog). Measures of performance included recognition rates and distances for signs, as well as detection rates, distances, and avoidance behaviors for hazards. Contrast acuity and sensitivity were also measured to evaluate possible correlations with driving performance. RESULTS: No statistically significant differences between the IOL groups were found in 26 of 30 comparisons (86.7%). The monofocal group performed better than the multifocal group in comparisons in which there were statistically significant differences: the percentage of correctly recognized warning signs at night in clear weather (P = .028), sign recognition distances for guide (P = .030) and warning (P = .036) signs in fog, and the detection distance for 1 of 4 hazards (suitcase; P = .026). Correlation coefficients between driving performance and low-contrast acuity and sensitivity were statistically significant; however, they were low and not likely predictive of driving performance. CONCLUSION: Differences between patients with bilateral multifocal IOLs and those with bilateral monofocal IOLs were detected; however, the results indicate no consistent difference in driving performance and safety.

Aged↗

PubMed1994

Prevalent attitudes regarding residency training in ocular anesthesia.

PURPOSE: To determine the current level of formal training in ocular anesthesia provided to nonophthalmologist physicians, the rationale for this training or lack thereof, and the perceived need for this training by anesthesia residency training programs. METHODS: A two-page survey questionnaire was forwarded to all residency directors of ophthalmology and anesthesia training programs listed with the American Medical Association. A second mailing followed 2 months after the initial mailing if no response was received from a particular program. RESULTS: An overwhelming response of 92% of ophthalmology programs and 76% of anesthesiology programs was achieved. In 93% of ophthalmology programs and 77% of anesthesiology programs, no formal training was provided to nonophthalmologist physicians in retrobulbar or peribulbar anesthesia. In addition, 78% of ophthalmology and 65% of anesthesiology programs denied having any plans to provide this training even though 40% of the anesthesia departments wanted to initiate and coordinate such training. CONCLUSIONS: Currently, few ophthalmology programs offer formal training to anesthesiology residents in ocular anesthesia. Following are the predominant factors involved in this decision: (1) the operating surgeon is ultimately responsible for any complications; (2) there is a lack of knowledge of orbital anatomy and axial eye length by anesthesia personnel; and, most importantly, (3) there is a brief episodic nature in which anesthesia residents encounter ophthalmologic procedures resulting in minimal opportunities for training and experience from which the residency training program could ensure quality outcome and proper credentialling.

Anesthesia, Local↗

PubMed1994

Diagnosis and management of diabetic retinopathy.

More frequent testing may sometimes be required, but annual comprehensive eye examinations generally seem best for uncovering early diabetic retinopathy and initiating treatment. Prevention and stabilization may be aided by tightly controlled diabetes.

Diabetic Retinopathy↗

PubMed1991

Phenylephrine prodrug. Report of clinical trials.

The authors evaluated the mydriatic effect of phenylephrine oxazolidine prodrug, a lipophilic sympathomimetic that undergoes hydrolysis to phenylephrine as it passes through the cornea and aqueous humor. Double-masked clinical trials were performed randomizing 66 healthy subjects to receive either the silicone vehicle as a placebo, 10% viscous phenylephrine hydrochloride (HCl), or prodrug in 0.25%, 0.50%, or 1.0% concentrations. A mean horizontal pupillary diameter of 8.8 mm was achieved in 30 minutes in those receiving 1% prodrug versus 6.5 mm obtained at 30 minutes with 10% viscous phenylephrine HCl. Statistically, this difference was highly significant at P less than or equal to 0.0001. There were minimal systemic or ocular adverse effects from any preparation.

Administration, Topical↗

PubMed1990

Myopia induced by vitreous hemorrhage.

Six of 11 children developed myopia in one eye after vitreous hemorrhage. None had retinopathy of prematurity, glaucoma, aphakia, or scleral buckling. In seven children developing vitreous hemorrhage before 1 year of age, six exhibited a myopic anisometropia in the affected eye of 1.37 to 12.00 diopters (mean, -4.7 diopters; S.D., 4.0). The degree of myopia correlated with the age of onset and duration of media opacification. In the child without myopia, the hemorrhage did not obscure the posterior pole. None of the four children whose hemorrhage occurred after 2 1/2 years of age showed myopic anisometropia (mean, +0.16 diopters; S.D., 0.24). We conclude that vitreous hemorrhage occurring in infancy is strongly associated with the development of myopia in the affected eye.

Aging↗