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Biomedical subjects

M J Moritz

Publications and source records attributed to M J Moritz.

62 records · Page 4Linked to original sources

Atypical electromyographic findings in pronator teres syndrome.

The electrodiagnostic differentiation between pronator teres syndrome and entrapment of the median nerve at the ligament of Struthers is generally thought to be aided by the absence of electromyographic (EMG) findings in the pronator teres muscle in pronator syndrome. This report describes a patient with surgically documented pronator teres syndrome who had EMG changes in the m. pronator teres, which was apparently innervated as or after the median nerve passed through. It is concluded that EMG abnormalities in the m. pronator teres should not alone be used to distinguish pronator teres syndrome from entrapment of the median nerve at the ligament of Struthers.

Diagnosis, Differential↗

Use of freshly isolated capillary endothelial cells for the immediate establishment of a monolayer on a vascular graft at surgery.

Endothelial seeding of vascular graft surfaces may lead to a less thrombogenic surface. We examined the feasibility of using microvessel endothelial cells derived from human fat for seeding purposes. Human fat was treated with collagenase for 24 minutes, washed, and purified in a Percoll gradient separation. This yielded 1.25 +/- 0.45 X 10(6) cells/gm of fat. After a 1-hour incubation on plasma-coated Dacron, 2.8 +/- 1.5 X 10(4) cells remained firmly adherent to the surface. When exposed to flow for 2 hours at a shear stress of 0 to 80 dyne/cm2, between 50% and 100% of the initially adherent cells remained adherent. Statistical analysis of this data failed to demonstrate a strong relationship between the number of adherent cells and the shear rate. Scanning electron microscopy demonstrated endothelial cells in various stages of attachment to the plasma-coated Dacron. Although most cells were still round and only focally attached to the surface, some cells were maximally flattened, forming cell-to-cell contact. Because of the high cell yield and the firm adherence characteristics, we conclude that microvessel endothelial cells may offer the possibility for confluent endothelial cell seeding of a graft at the time of surgical implantation without the need for cell culture.

Adipose Tissue↗

Recovery of native liver after heterotopic liver transplantation for fulminant hepatic failure: MR studies.

Heterotopic liver transplantation involves the transplantation of an auxiliary liver into the subhepatic space while leaving the native liver intact. This procedure is a viable treatment for select patients with fulminant hepatic failure who fail medical treatment. The MR-pathologic correlation of a patient who developed graft failure and recovered full function of her native liver after heterotopic liver transplantation is presented. Based on the imaging and biopsy findings, immunosuppression was withdrawn and the patient remains asymptomatic with normal liver function. Interpreters of imaging studies in this group of patients should not restrict their attention to the heterotopic graft. The return of the native liver in both a structural and functional sense is a clinically important phenomenon that can be detected with MR imaging.

Adult↗