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Biomedical subjects

M J Pérez Alvarez

Publications and source records attributed to M J Pérez Alvarez.

6 recordsLinked to original sources

[Panuveitis as a possible ophthalmic complication of Kikuchi-Fujimoto disease].

CLINICAL CASE: A 37 year old female with histologically proven Kikuchi-Fujimoto disease is presented. She developed panuveitis, vasculitis and subretinal macular infiltrate, probably as a recurrence of the disease. Immunosuppressive treatment (methotrexate) was initiated in the absence of response to systemic steroid therapy and threat to vision owing to macular involvement. DISCUSSION: Ophthalmic complications of Kikuchi-Fujimoto disease are unusual. We discuss differential diagnosis and emphasize the aggresiveness of our case.

Adult↗

[Tuberculous meningitis. One case: ophthalmic complications].

CASE REPORT: An 18 year old female suffering from tuberculous meningitis with bilateral amaurosis, ophthalmoplegia, other cranial nerve palsies and loss of consciousness, is presented. DISCUSSION: Tuberculous meningitis is a rare cause of basal arachnoiditis with a bad prognosis. Possible causes of visual acuity loss and ophthalmoplegia are discussed and a favourable outcome without sequelae is noteworthy in our case.

Adolescent↗

[Tuberculous peripheral multifocal choroiditis].

CASE REPORT: A healthy 57 year-old woman with past untreated pulmonary tuberculosis, disclosed a bilateral uveitic syndrome characte rized by iritis, vitreitis, multiple peripheral retinal punched-out lesions, and cystoid macular edema. Systemic evaluation was unremarkable except for a 30 mm tuberculin skin test. Relapses occurred after oral and periocular corticosteroids were interrupted, but the inflammation completely disappeared after a 6 month course of isoniazid, rifampicin and pyrazinamide. DISCUSSION: Intraocular tuberculosis should be considered as a treatable cause of peripheral multifocal choroiditis, after ruling out other etiologies.

Adrenal Cortex Hormones↗

[Benign concentric annular macular dystrophy: two cases].

CLINICAL CASE: We present two cases of two sisters with the presumed diagnosis of benign concentric annular macular dystrophy. Age was 16 and 22 years old respectively. They presented with decrease in visual acuity and annular atrophy of the macular retinal pigment epithelium. The fluorescein angiography showed < > pattern and the electrophysiologic tests were normal. DISCUSSION: The prognosis of this dystrophy is fairly good, therefore it is important to make an accurate diagnosis to be able to distinguish it from others entities, mainly those presenting < > pattern in fluorescein angiography. We emphasize the usefulness of fluorescein angiography and electrophysiologic test (electroretinogram and electrooculogram).

Adolescent↗

[Cavernous sinus aneurysms. Treatment and evolution].

CASE REPORT: Two clinical cases of painful ophthalmoplegia from a cavernous sinus syndrome induced by carotid intracavernous aneurysm are presented. Two women presenting similar clinical patterns: total restriction of ocular movements, pthosis, alterations in the pupil and intense cephalalgia of sudden onset. Carotid aneurysms were found to be responsible for these clinical patterns. A carotid embolization was performed in one of the cases while a < > attitude was adopted for the other. DISCUSSION: Both cases showed similar favorable evolution, after a follow up period of one year. We concluded that in these cases a close collaboration with other specialties is required in order to adopt the most adequate therapeutic option.

Aged↗

[No X-chromosome linked juvenile foveal retinoschisis].

PURPOSE: To describe the clinical characteristics of two cases of juvenile foveal retinoschisis in women with an atypical hereditary pattern, no X-chromosome linked. An autosomal recessive inheritance is proposed. METHODS: Two generations of a family (5 members) in which only two sisters were evaluated. The complete examination of these two cases includes retinography, fluorescein angiography, automated perimetry, color vision testing, electroretinogram, electrooculogram and visually evoked potentials. RESULTS: Comparing our cases with the classic form of X-linked juvenile retinoschisis, they are less severely affected. The best visual acuity and the less disturbed or even normal electroretinogram confirm this fact. We emphasise the existence of isolated plaques of retinal pigment epithelium atrophy with perivascular pigment clumps without foveal schisis in one patient, which could represent an evolved form of this entity. CONCLUSIONS: The hereditary foveal juvenile retinoschisis in women suggests an autosomal inheritance (autosomal recessive in our cases) and presents less severe involvement (Arch Soc Esp Oftalmol 2002; 77: 443-448).

Adolescent↗