Biomedical subjects
M J Prewett
Publications and source records attributed to M J Prewett.
Dietary changes associated with electroconvulsive shock.
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Electroconvulsive shock and the estrous cycle in the rat.
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Effects of electroconvulsive shock on food and water intake in the rat.
Forty-two male rats were habituated to laboratory conditions for four weeks under constant light conditions. Food and water intakes were recorded daily. Following the habituation period half of the animals were given electroconvulsive shock (ECS) and half Sham-ECS (SECS). ECS treatments produced significant decrements in both food and eater intakes which returned to baseline levels after three days.
Alpha activity suppression and enhancement as a function of feedback and instructions.
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Factors in the modification by isolation of electroconvulsive shock-produced retrograde amnesia in the rat.
It has been demonstrated that placing rats in a sensory-restricted environment during the electronconvulsive shock- (ECS) retention interval following 1-trial appetitive learning will prevent or eliminate ECS-produced retrograde amnesia. The first study replicated this finding with a 1-trial aversive learning task, indicating that this effect is not task specific. The second study attempted to determine whether illumination or the restricted environment was the crucial factor in this penomenon. Rats placed in the light during the ECS-retention interval, whether restricted or in the colony, demonstrated retrograde amnesia after ECS. However, rats left in the dark during this interval demonstrated little, if any, retention deficit particularly if this condition was combined with sensory isolation. These studies further indicate that manipulation of the general environment of the animal after ECS can alter ECS-produced retention losses.