[Epidemiology of coronary atherosclerosis in Belgium].
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Adult↗
Biomedical subjects
M J Segers
Publications and source records attributed to M J Segers.
Intimal hyperplasia in reversed and in situ vein grafts: an intra-individual canine study.
The apparent superiority of the in situ vein graft over the reversed vein graft in long arterial reconstructions has been explained by a superior hemodynamic performance and a reduction of intimal hyperplasia in the in situ graft. To examine this, an intracomparative canine study was performed with respect to the progression of intimal and medial changes in both in situ and reversed vein grafts. Paired femoropopliteal artery grafts were inserted in six dogs using the in situ technique in the right leg and the reversed technique in the left leg. The grafts were excised at 1 day, 3 months, and 6 months after operation. Substantial changes were shown both in histologic structure and in absolute intimal and medial thickness, without a significant intra-individual difference between in situ and reversed grafts. The intima-to-media ratio increased in the first 3 months and stabilized in the 3- to 6-month interval. In this intra-individual canine study preservation of adventitia and vasa vasorum had no biologic effect on the development of the same intimal changes in the midsection of reversed and in situ vein grafts.
Animals↗
[Anxiety self-rating and myocardial infarction (author's transl)].
This study addresses to critical issues related to the role of anxiety in myocardial infarct. Is the predictive value of the Anxiety Scale Questionnaire (ASQ) to be found in content of items and its self-rating by the subject or in response style to the questionnaire? Would anxiety play in certain circumstances a positive role in that it drives the individual to seek early medical treatment? Differences in anxiety scores, response style indices and factorial structures of the ASQ items reveal : 1. myocardial infarction subjects have higher, but not significantly higher, anxiety scores relative to healthy volunteers to an atherosclerosis screening test and healthy control individuals matched for age, sex and socio-economic status, 2. healthy volunteers are characterized by extreme response style that could reveal their involvement in the testing situation; 3. control individuals show a tendency to intermediate response; 4. the lack of invariance of factorial structure across the three groups suggests that each of them has a specific organization of anxiety. Scale-checking style, though strongly associated with the content of items, could have a predictive value since, anxiety levels being equal, subjects may be differently involved in their answers. The assumption is supported by the specific organization of anxiety evidenced in each group considered. A relation between such organization and preventive behaviour is not infirmed by the present data and ought to be further analyzed.
Anxiety↗