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Biomedical subjects

M J Sexton

Publications and source records attributed to M J Sexton.

4 recordsLinked to original sources

Alcohol consumption among pregnant smokers: effects of a smoking cessation intervention program.

This study describes patterns of alcohol consumption among pregnant women who participated in a randomized clinical trial of smoking cessation intervention. Data on alcohol habits were obtained prospectively prior to the 18th week of gestation and during the 8th month of pregnancy. Average alcohol intake for both groups was reduced primarily prior to registration for prenatal care. The smoking cessation intervention reduced smoking during pregnancy but had no effect on alcohol intake.

Alcohol Drinking

Developmental screening using parent report.

The need for comprehensive screening of pediatric populations to identify potential development problems is widely accepted. The lack of systematic screening in pediatric practice is due to several factors, including the need for an efficient, reliable instrument and the limited professional time available for screening. The present study compares the effectiveness of a screening instrument, the Minnesota Child Development Inventory, with an individually administered psychological test, the McCarthy Scales of Child Development. Because the former uses a parent report format, little professional time is involved in screening. The Minnesota and McCarthy were administered to 364 children who were within 1 month of their third birthday. Four of five Minnesota scores correlated significantly (p less than 0.0001) with each of the six McCarthy subscores. The Minnesota appears to be an efficient, valid test that would facilitate comprehensive screening in a pediatric population.

Adolescent

Efficacy of two dosage schedules of cephalexin in dermatologic infections.

Is the administration of oral antibiotics four times a day as necessary as some pharmacokinetic studies indicate? The efficacy of cephalexin administered twice a day was compared to the same drug administered four times a day for the treatment of skin and skin structure infections due to staphylococcus and/or streptococcus. The 154 outpatients in this four-clinic study ranged in age from 1 month to more than 70 years. A random number table was used to assign patients to either the twice a day or the four times a day regimen. The total daily dosage was the same in each regimen. Administration twice a day proved equally effective to the four times a day regimen. Both regimens were more than 97 percent effective and side effects were minimal.

Adolescent