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Biomedical subjects

M J Tassignon

Publications and source records attributed to M J Tassignon.

At least 37 records · Page 2Linked to original sources
PubMed1998

Secondary closure of posterior continuous curvilinear capsulorhexis in normal eyes and eyes at risk for postoperative inflammation.

PURPOSE: To observe the posterior continuous curvilinear capsulorhexis (PCCC) after cataract surgery in control eyes and eyes with an increased risk for postoperative inflammation. SETTING: Department of Ophthalmology, University Hospital Antwerp, Belgium. METHODS: After phacoemulsification, a PCCC was performed before intraocular lens (IOL) implantation in 20 eyes of 18 patients with ocular or systemic conditions that predisposed them for increased postoperative inflammation; e.g., diabetes, uveitis, retinitis pigmentosa (inflammation group). These eyes were compared with 20 eyes of 16 patients who had the same surgical procedure but did not present a history of medical or ocular pathology (control group). The postoperative follow-up was 6 months to 3 years. Reclosure of the PCCC was evaluated by anterior segment photographs. The reclosure was classified as partial when newly formed tissue was present at the PCCC margin and total when the proliferation covered the entire PCCC area. RESULTS: Three types of PCCC reclosure were found: fibrotic, Elschnig pearl or multilayer, and monolayer. All 3 were seen within or at the margin of the PCCC area. Reclosure (total and partial) occurred in 8 eyes (40%) in the control group and 10 (50%) in the inflammation group. Total reclosure was more frequent in the inflammation group (4 eyes [20%]) than in the control group (1 eye [5%]). Monolayered or multilayered cellular proliferation was present in 8 eyes (40%) in the control group and 4 eyes (20%) in the inflammation group; fibrotic proliferation was found in the inflammation group only (7 eyes [35%]). CONCLUSION: Reclosure of the PCCC occurred in both groups, although the frequency of reclosure was slightly higher in the inflammation group. Although PCCC does not prevent posterior capsule opacification in all cases, it is useful in specific situations.

Adolescent↗
PubMed1998

Strampelli osteo-odonto-keratoprosthesis: case report.

Case report of a patient equipped with an osteo-odonto-keratoprosthesis in both eyes (left in 1968 and right in 1971). The left eye was recently enucleated because of unbearable pain, in an eye without light perception since 20 years. The histology shows an ancient retinal detachment and an eye completely filled with blood. Indications and complications of the technique are discussed.

Corneal Transplantation↗
PubMed1998

Biopsy in single extraocular muscle hypertrophy.

Single extraocular muscle hypertrophy is usually caused by an orbital pseudotumour. We present two cases in which unexpectedly a malignancy was diagnosed during work-up of a suspected orbital pseudotumour.

Aged↗
PubMed1997

Centration of intraocular lenses with circular haptics.

PURPOSE: To evaluate two intraocular lens (IOL) models with a circular haptic configuration designed to better distribute forces within the capsular bag over 360 degrees. SETTING: University and Maria Middelares hospitals, Antwerp, Belgium. METHODS: Two IOLs with circular haptics were evaluated for 6 months after implantation: a one-piece, all-poly(methyl methacrylate) (PMMA), Corneal IS M 5.5 lens with a 5.5 mm biconvex optic, overall diameter of 9.8 mm, and two semicircular open haptics (n = 103); a plano-convex, all-PMMA, modified Anis lens with a 5.5 mm plano-convex optic, total diameter of 10.0 or 11.0 mm (depending on diopter), and closed-loop haptics (n = 335). All lenses were inserted through a 5.5 mm scleral incision after phacoemulsification and placed in the capsular bag through a 4.5 mm curvilinear capsulorhexis. The IOLs centered without being rotated. RESULTS: Six months after implantation, the IOL optics were well centered, even in eyes with an eccentric capsulorhexis (19%). In two eyes with partial zonulysis and in seven with posterior capsule rupture, decentration of less than 0.5 mm was observed. Both lenses provided uniform capsular support without causing stress lines in the posterior capsule. There were no cases of capsule contraction syndrome. Posterior capsule fibrosis reducing visual acuity occurred in 4% of eyes in both series. CONCLUSION: The Corneal IS M 5.5 and the Anis lens with circular haptics prevented late optic decentration and, therefore, would be useful in cases of eccentric capsulorhexis, partial zonulysis, anterior radial tears, and posterior capsule rupture. These IOLs may also prevent capsular contraction.

Adult↗
PubMed1997

Nd:YAG laser posterior hyaloidotomy for the treatment of a premacular vitreous floater.

A 63-year old man, with a large central vitreous floater, underwent a Nd:YAG laser posterior hyaloidotomy. Although the vitreous floater disappeared from the central optical axis, visual acuity did not improve. Microperimetry performed with the SLO revealed an absolute scotoma, which corresponded well in shape and dimension with the original vitreous floater. This finding suggests that a fragment of the neurosensory retina became detached together with the internal limiting membrane in the process of the vitreous collapse.

Aluminum Silicates↗
PubMed1997

[Treatment of hypermetropia using the Holmium laser--laser thermokeratoplasty (LTK)].

The results of two year follow-up after Holmium LTK are presented. The choice of the technique was justified based on experimental, technical and anatomo-pathological data as well as on the property of the corneal collagen fibers to shrink at a temperature of 60-70 degrees C. Although the immediate results were encouraging, we found an important regression after two years follow-up, resulting in a final correction of maximally 1.5 D, independent on the degree of hypermetropia to be treated. These results were obtained with the "contact" method, which is in our experience slightly superior to the "non-contact" technique. The question is whether the regression will continue with time or will stabilize and remain at 1.5 D of hyperopic correction.

Epithelium, Corneal↗
PubMed1997

[Medical treatment in laser (PRK) photoretractive keratotomy].

The need of medical treatment after photorefractive surgery has been studied by reviewing the literature on the subject and comparing their conclusions with our clinical experience. Considering the pre-operative and immediate post-operative medical treatment, there is a large consensus since the aim is treatment of pain and prevention of superinfection. The post-operative considerations for medical treatment are more controversial and can be considered as to be useful or possibly useful.

Adrenal Cortex Hormones↗
PubMed1996

Central retinal artery occlusion after spinal surgery.

Central retinal artery occlusion can be caused by excessive extrinsic pressure on the eyeball during surgery. It is a rare and severe complication after elective spinal surgery. The authors report a case of central retinal artery occlusion in an adult after posterior lumbar spinal fusion in which a rectangular headrest was used.

Adult↗
PubMed1996

Secondary closure of posterior continuous curvilinear capsulorhexis.

PURPOSE: To examine the hypothesis that removing the center of the posterior capsule would prevent posterior capsular opacification (PCO). SETTING: Department of Ophthalmology, University Hospital Antwerp, Belgium. METHODS: A posterior continuous curvilinear capsulorhexis (CCC) was done before intraocular lens (IOL) implantation in eyes at risk for PCO (uveitic, young adult), retinal detachment after neodymium:YAG (Nd:YAG) laser capsulotomy (highly myopic) or for cystoid macular edema (uveitic, diabetic) and in eyes in which the posterior capsule was opaque intraoperatively. The 51 eyes of 40 patients had a follow-up ranging from 6 months to 2 years. RESULTS: Four eyes (8%) developed partial closure of the posterior CCC without vision impairment; 6 eyes (12%) had total closure, of which 2 (4%) had a loss of two or more Snellen lines necessitating an Nd:YAG laser capsulotomy. CONCLUSION: Young adult eyes and eyes with underlying diabetic retinopathy or uveitis are at risk for total closure of the posterior CCC. Only young adult eyes required Nd:YAG laser capsulotomy after the posterior CCC.

Adult↗
PubMed1996

Blindness due to electrocoagulation following functional endoscopic sinus surgery.

A case is presented with irreversible blindness in one eye and restriction of the infratemporal visual field in the other eye, due to electrocoagulation performed for delayed bleeding after functional endoscopic sinus surgery (FESS). Although blindness due to rhinosurgery is a well-known, but rare complication, a review of the recent literature did not reveal a similar incident. The use of electrocoagulation especially under conditions of poor visualization, that may be the case in post-operative bleeding following (endoscopic) sinus surgery, is strongly discouraged.

Adult↗
PubMed1996

Therapy-resistant corneal ulcer in a six-year old patient.

Throughout this case emerges the importance of a thorough ophthalmological examination of children who have suffered an eye trauma. A double eversion of the upper eyelid under narcosis may be necessary to detect the presence of a foreign body.

Anti-Bacterial Agents↗
PubMed1996

Diagnosis of a masked bilateral congenital superior oblique palsy.

Some patients in whom the diagnosis of a purely unilateral congenital superior oblique palsy was made, developed signs of a palsy in the fellow eye after surgery was done. A review of all diagnostic tests used in discovering the presence of a masked bilateral superior oblique palsy is given. The usefulness of the occlusion-test, which is often forgotten, is illustrated.

Adult↗
PubMed1996

Tubulo-interstitial nephritis-uveitis (TINU)-syndrome with posterior uveitis.

A case of TINU-syndrome with complications in the posterior segment is reported. A 15-year old boy presented, eight months after an acute tubulo-interstitial nephritis, a bilateral anterior uveitis, followed by an unilateral posterior uveitis with papillitis. The treatment with oral and topical corticosteroids was successful.

Acute Disease↗
PubMed1996

Secondary closure of posterior continuous circular capsulorhexis.

We examined the hypothesis that removing the center of the posterior capsule would reduce the risk for posterior opacification (PCO). We considered the prevalence of post-operative complications after PCCC like retinal detachment and cystoid macular edema, as found after Nd-YAG laser capsulotomy.

Adult↗
PubMed1995

Isoenzymic patterns of tyrosinase in the rabbit choroid and retina/retinal pigment epithelium.

Tyrosinase in crude extracts from the adult rabbit choroid and retina/retinal pigment epithelium was found to be differently affected by the inhibitors sodium metabisulfite, cyanide, diethyldithiocarbamate and 2,2'-dipyridyl:the latter inhibited the activity in the retina/retinal pigment epithelium extract after 24 hr of incubation, but not that in the choroid. The first three inhibitors, on the other hand, inhibited the activity in the choroid extract, but not in the retina/retinal pigment epithelium extract, after 3 hr of incubation. Both extracts contained one insoluble and two soluble isoenzymes. The mobilities and the apparent molecular weights of the soluble isoenzymes (more markedly so for the most rapidly migrating) differed, as revealed by polyacrylamide gel electrophoresis, resulting in distinct isoenzymic patterns. We suggest that such patterns may be related to the characteristic melanogenic features of the retina/retinal pigment epithelium and choroid.

Animals↗
PubMed1995

Central retinal artery occlusion after back surgery: a case report.

Central retinal artery occlusion can be caused by excessive extrinsic pressure on the eyeball during surgery. It is a well-known and severe complication after elective back surgery. The authors report a case of central retinal artery occlusion in an adult after posterior lumbar fusion in which a rectangular headrest was used.

Adult↗
PubMed1995

Surgical treatment of myogenic blepharoptosis.

We describe the surgical approach of two patients with myogenic blepharoptosis. The ptosis is caused by a glycogenosis type II (Pompe disease) in the first case and is due to a juvenile, chronic progressive external ophthalmoplegia (Kearns-Sayre syndrome) in the second case. The first patient presented a unilateral ptosis. The ptosis in the second patient was bilateral and manifest. The eyelids could only be opened manually. A resection of the palpebral levator muscle was carried out under local anesthesia. The choice of the technique will be explained. The amount of levator resection was calculated considering the residual eyelid motility and Bell's phenomenon. Electronmicroscopy of the resected levator muscle will be discussed.

Adult↗