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Biomedical subjects

M Jamra

Publications and source records attributed to M Jamra.

At least 19 recordsLinked to original sources

[Normal hematologic parameters].

Hematological studies by several Brazilian and other Latin-American authors who give parameters considered as normal for different populations have been reviewed. Results showed significant differences, due to social, environmental and nutritional factors as well as to different methodological procedures and also to age, sex, race, occupation and other individual characteristics. Three Brazilian studies were selected in the light of the wide variety of parameters included. Ranges are presented as a demonstration of the variations in such samples, presumably considered "normal" by the respective authors presumably "normal". One of the purposes of the present study is to establish the basis for future investigation into the effects of industrialization on the ranges of the hematological parameters of individuals taken to be normal.

Adolescent

Increased levels of eosinophil-derived PAF-acether activity in a patient with idiopathic hypereosinophilic syndrome.

We describe a patient with idiopathic hypereosinophilic syndrome (IHS) having PAF-acether activity corresponding to 4 X 10(-11) M/10(6) eosinophils as determined by standard aggregation curves prepared with purified PAF-acether. These data suggest that the increased PAF-acether content in patients with IHS may play a role in the development of thrombotic phenomena through platelet activation.

Adult

[Progressive antithrombin activity in blood of pregnant women and neonates in the first four days of life (author's transl)].

Progressive antighrombin activity was assayed in 45 term infants in the first four days of life, in 20 cord blood specimens and in the blood of 20 pregnant women (at term). In the term infants a positive correlation was shown between progressive antithrombin and postnatal age. No correlation could be demonstrated with sex, ethnic group or type of delivery. Maternal antithrombin activity was shown to be moderately decreased, maternal values being closely related to cord blood values.

Antithrombin III

Epstein-Barr virus infections in Brazil. II. Hodgkin's disease.

Sixty-seven cases of Hodgkin's disease (HD) occurring in São Paulo, Brazil, were studied. Males with HD predominated over females 2.3 to 1. Sixty-six percent of the cases occurred in patients under 30 years of age, 31.7% under 20 years of age, and only 7.5% after 50 years of age. Lymphocyte predominance and mixed cellularity histologic types were most common in patients less than 15 years old, and nodular sclerosis was most common in the 15- to 19-year-old group. Sera from all patients had antibody to the viral capsid antigen (VCA) of Epstein-Barr virus (EBV). The geometric mean titer (GMT) of VCA antibody with the use of Jijoye cells as antigen was 1:162, and 31.3% of patients had titers of 1:320 or more; in controls, the GMT was 1:67 and 3.8% had titers of 1:320 or more. Similar results were obtained when EB-3 cells were used as antigen. The highest titers occurred in males, in mixed cellularity and lymphocyte depletion forms, and in stage 2 of illness. EBV-specific IgM antibody and heterophile antibody levels were not elevated, but 20.5% of the HD patients had antibody to the early antigen of EBV present in their sera. Antibody levels for herpes simplex virus, cytomegalovirus, rubella, measles, parainfluenza viruses, and papovavirus were not significantly elevated over those in matched controls.

Adolescent