Biomedical subjects
M Javid
Publications and source records attributed to M Javid.
Four brief reports on long-term results of intradiscal chymopapain.
Five- to 12-year statistics for 842 patients treated with intradiscal chymopapain are presented by four observers. While the results are presented in different formats, long-term satisfactory results can be reported for 81% of the patients, with a range of 71%-83%.
Suspected cancer-causing agents in the hospital environment.
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Rebound phenomenon.
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Nonsurgical management of spontaneous intracerebral hematoma.
This report describes our experience with the use of osmotic diuretics, governed by continuous monitoring of intracranial pressure (ICP), as the primary treatment for 12 consecutive patients suffering from an acute, supratentorial intracerebral hematoma. In all cases the hematoma, as shown by computed tomographic scan, had a long axis of greater than 4.0 cm. ICP and cerebral perfusion pressure were successfully maintained within the assigned limits in all patients, and in none was surgical evacuation required. There was one death during the 6-month follow-up period. With appropriate weighting to differences in admission status, statistical comparison of the patient outcome in the present series with that reported by McKissock et al. suggests that ICP monitoring can improve the outcome of conservatively (and perhaps surgically) treated patients.
Clinical applications of computerized fluoroscopy: the extracranial carotid arteries.
Preliminary results obtained with a new computerized fluoroscopic apparatus in examination of the extracranial carotid arteries are described. All patients had clinical signs of symptoms of extracranial occlusive vascular disease. In most cases, image quality was sufficient to display patency of the internal carotid arteries, with excellent correlation between intravenous and conventional angiography. While the new technique is not totally noninvasive, it does eliminate many of the risks and costs of conventional arteriography.
Neurosurgical experience with carotid endarterectomy at University Hospitals (1954-1976).
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Office treatment of craniocerebral trauma.
The first physician to see a victim of craniocerebral trauma must provide necessary first aid and then rapidly assess the type and extent of injury. The level of consciousness is the most important guide to severity of injury, and frequent appraisal is essential until the critical period is determined to have passed.
Proteins from human cerebrospinal fluid: binding with nucleic acids.
Cerebrospinal fluid (CSF) contains two groups of proteins that bind tightly to DNA and to polyriboguanylic acid, respectively. In certain diseases the amounts of a given nucleic acid bound by a constant volume of CSF may increase, while in others the amount of such proteins may be reduced. Binding of polyriboguanylic acid increased in CSF samples from patients with brain tumors, stroke, multiple sclerosis, and communicating hydrocephalus, but it significantly decreased in CSF samples from patients with obstructive hydrocephalus. These increases may or may not be proportional to the rise in total CSF proteins characteristic for these diseases. Elevated binding of DNA was observed in samples from patients with hydrocephalus, epilepsy, and cortical atrophy. The technique described may be applicable to the diagnosis of a variety of diseases of the central nervous system.
Glioblastoma multiforme. An analysis of the results of postoperative radiotherapy alone versus radiotherapy and concomitant 5-fluorouracil. (A prospective randomized study of 32 cases).
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The diagnostic significance of a protein binding nucleic acid in cerebrospinal fluid.
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An experimental and analytical investigation of an internal cooling technique.
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Evaluation of carbamazepine in the management of tic douloureux and other painful disorders.
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