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Biomedical subjects

M Javid

Publications and source records attributed to M Javid.

At least 19 recordsLinked to original sources

The mechanisms of Ni2+ ions sorption by AlPO4.

Sorption of Ni2+ ions by AlPO4 is studied as a function of concentrations and temperature at pH 7. Potentiometric titration, dissolution and FTIR studies are employed to determine the mechanism of the process of the uptake of Ni2+ ions which is found to be both the ion exchange and the surface precipitation of the corresponding metal phosphates. Freundlich equation is found applicable to the sorption data, and is employed to evaluate the thermodynamic parameters deltaH(o) and deltatS(o).

Adsorption↗

Sorption mechanism of Co2+ ions by AlPO4.

Sorption studies were conducted for Co2+ ions on AlPO4 at different concentrations and temperatures. Sorption of Co2+ was found to increase with increase in concentration and temperature. To determine the mechanism of the sorption process, dissolution of AlPO4 in the presence of Co2+ ions and desorption studies were performed which indicated the mechanism of sorption to be the ion exchange followed by precipitation. FTIR studies were also employed to confirm the proposed mechanism.

Adsorption↗

Activation of cerebellar climbing fibres to rat cerebellar posterior lobe from motor cortical output pathways.

1. The activation of climbing fibres projecting to the posterior lobe cerebellar cortex by focal stimulation of the cerebral corticofugal pathway was investigated in anaesthetised rats. Large climbing fibre responses were evoked in parts of crus II and paramedian lobule by stimulation of corticofugal fibres. Lesions of the pyramidal tract just rostral to the inferior olive substantially reduced these responses, suggesting that they were not mediated by relays in the rostral brainstem. 2. By comparison of latencies of climbing fibre responses evoked from different locations in the corticofugal pathway, the conduction velocities of the corticofugal fibres that mediate the responses were estimated to be 1.9 +/- 0.3 m s(-1) (mean +/- S.E.M.). The fastest conducting corticofugal fibres were estimated to conduct significantly faster (18.7 +/- 2.3 m s(-1)). 3. Climbing fibre responses with similar form and cerebellar distribution were evoked from sites in the pyramidal tract rostral and caudal to the inferior olive. This suggests that at least a proportion of the fibres that activate climbing fibres are corticospinal fibres. 4. Lesions of the dorsal column nuclei did not affect the climbing fibre responses evoked in crus II, and produced a relatively small reduction of the responses in the paramedian lobule. This implies that the climbing fibre responses were not exclusively mediated via the dorsal column nuclei. 5. Corticofugal evoked climbing fibre responses were mapped across the cerebellar hemisphere. At some sites they were co-localised with responses evoked by limb afferents. On the basis of limb afferent inputs and other work, these zones were tentatively identified as being functionally equivalent to the c1, c2 and d zones described in the cat.

Animals↗

Four brief reports on long-term results of intradiscal chymopapain.

Five- to 12-year statistics for 842 patients treated with intradiscal chymopapain are presented by four observers. While the results are presented in different formats, long-term satisfactory results can be reported for 81% of the patients, with a range of 71%-83%.

Chymopapain↗

Rebound phenomenon.

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Administration, Oral↗

Nonsurgical management of spontaneous intracerebral hematoma.

This report describes our experience with the use of osmotic diuretics, governed by continuous monitoring of intracranial pressure (ICP), as the primary treatment for 12 consecutive patients suffering from an acute, supratentorial intracerebral hematoma. In all cases the hematoma, as shown by computed tomographic scan, had a long axis of greater than 4.0 cm. ICP and cerebral perfusion pressure were successfully maintained within the assigned limits in all patients, and in none was surgical evacuation required. There was one death during the 6-month follow-up period. With appropriate weighting to differences in admission status, statistical comparison of the patient outcome in the present series with that reported by McKissock et al. suggests that ICP monitoring can improve the outcome of conservatively (and perhaps surgically) treated patients.

Adolescent↗

Clinical applications of computerized fluoroscopy: the extracranial carotid arteries.

Preliminary results obtained with a new computerized fluoroscopic apparatus in examination of the extracranial carotid arteries are described. All patients had clinical signs of symptoms of extracranial occlusive vascular disease. In most cases, image quality was sufficient to display patency of the internal carotid arteries, with excellent correlation between intravenous and conventional angiography. While the new technique is not totally noninvasive, it does eliminate many of the risks and costs of conventional arteriography.

Arterial Occlusive Diseases↗

Office treatment of craniocerebral trauma.

The first physician to see a victim of craniocerebral trauma must provide necessary first aid and then rapidly assess the type and extent of injury. The level of consciousness is the most important guide to severity of injury, and frequent appraisal is essential until the critical period is determined to have passed.

Brain Injuries↗

Chemonucleolysis.

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Chymopapain↗

Head injuries.

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Brain Concussion↗

Proteins from human cerebrospinal fluid: binding with nucleic acids.

Cerebrospinal fluid (CSF) contains two groups of proteins that bind tightly to DNA and to polyriboguanylic acid, respectively. In certain diseases the amounts of a given nucleic acid bound by a constant volume of CSF may increase, while in others the amount of such proteins may be reduced. Binding of polyriboguanylic acid increased in CSF samples from patients with brain tumors, stroke, multiple sclerosis, and communicating hydrocephalus, but it significantly decreased in CSF samples from patients with obstructive hydrocephalus. These increases may or may not be proportional to the rise in total CSF proteins characteristic for these diseases. Elevated binding of DNA was observed in samples from patients with hydrocephalus, epilepsy, and cortical atrophy. The technique described may be applicable to the diagnosis of a variety of diseases of the central nervous system.

Alcoholism↗